What are the final metabolic pathways of Nadh H produced in glycolysis

In the absence of oxygen, NADH+H+ produced by the dehydrogenation reaction in the EMP pathway is handed over to pyruvate to produce lactate. If oxygen is present, NADH+H+ enters the mitochondria for oxidation.

There are three enzymes that are the most critical:

1. Glucokinase, which catalyzes the eventual conversion of glucose into glucose-6-phosphate.

Phosphofructokinase, which catalyzes the conversion of fructose-6-phosphate to fructose-1,6-bisphosphate.

3. Pyruvate kinase, catalyzing phosphoenolpyruvate and ADP to produce enolpyruvate and ATP

These three enzymes are the most critical because the reactions they catalyze are irreversible.

Report. Ions in living organisms cannot exist alone, which is different from the concept of solution in chemistry. Therefore, the H+ produced by dehydrogenation must be captured by a carrier, such as NAD+.

2.The resulting NADH goes through the electron transport chain, and the oxidized respiratory chain produces energy for the same purpose as glycolysis. After the energy is generated, H+ is consumed and becomes water.

3.Without oxidation, NaDH cannot capture the H+ produced after dehydrogenation. This leads to the obstruction of the glycolytic pathway, and the production of ATP increases due to excessive NADH, which will feedback the activity of inhibiting enzymes.

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There are 50 high school chemistry spike formulas that do not participate, including glucose-6-phosphatase, phosphoenolpyruvate carboxinase, pyruvate carboxylase, fructose bisphosphatase-1, etc. Glycolysis is the anaerobic oxidation of sugar, catalyzing the glycolysis reaction, there will be many enzymes, and these enzymes exist in the cytoplasm, in which under the catalysis of phosphaglycerate kinase (PGK), bisphoglycerate to produce 3-phosphoglyceric acid, and at the same time, the high-energy phosphate group on its C1 is transferred to ADP to generate ATP, and the energy generated during the oxidation of this substrate directly phosphorylates ADP to ATP, which is called substrate-level phosphorylation(substrate level phosphorylation).The reaction catalyzed by this kinase is reversible.

According to the latest research, the energy released by the energy released by each molecule of NADH after being transported through the respiratory chain and finally combined with oxygen to form HO can produce about one ATP molecule (in the past, it was thought to produce 3 ATP).

The energy released by a FADH after similar electron transfer can produce about one ATP molecule (in the past, it was thought to produce 2 ATP molecules).

Pyruvic acid. The glycolysis process is the process of decomposing glucose to produce pyruvate, and there are 10 steps of enzyme-catalyzed reaction in the whole process.

Step 10 of glycolysis:

Generation of pyruvate.

Catalyzed by pyruvate kinase, the phosphoenolpyruvate molecule high-energy phosphate group is transferred to ADP to generate ATP, which is the second substrate-level phosphorylation reaction of the glycolytic pathway, which requires the participation of Mg2+ and K+, and the reaction is irreversible.

The question is a little sharper ......NADH is not oxidized, it is always NADH, and only after oxidation can it be changed from NAD+ to NADH again, otherwise how to call it cyclic ......The process of this glycolysis ......Well, I really don't know how to say this question, it's like this ==

During glycolysis, one glucose produces 2 molecules of pyruvate, 2 molecules of ATP, 2 molecules of NADH, and 2 molecules of water are obtained.

The end product of the glycolysis process ().

a propionyl coa

b Acetone. c Pyruvate.

d Malonyl COA

Correct answer. c Answer analysis.

Test Center] Substance metabolism.

Analysis] Acetyl CoA is the only carbon atom in all the fatty acid molecules synthesized in vivo, but only one molecule is acetyl CoA in the synthesis process, and the others need to be carboxylated to form malonyl Coa before entering the pathway of synthesizing fatty acids. The 10th (final) step of glycolysis is the transfer of phosphate from the phosphoenolpyruvate molecule to ADP catalyzed by pyruvate kinase to produce ATP and pyruvate, and the glycolysis process is completed.

In some books, the pyruvate to lactate process is counted as the final step, with lactate as the final product, but the mainstream view is still pyruvate.

I don't know, I don't know, I don't know what this is Sister Tang's metabolism?

a.Reduces pyruvate to lactate.

b.The trans-glycerol phosphate shuttle system quietly enters mitochondrial oxidation.

c.It is oxidized into human mitochondria through the malic acid shuttle system.

Phosphoglyceric acid is reduced to glycerol 3-phosphate.

e.All of the above is true.

Correct answer to the Lu case: a

The way of Nadh + H+ during glycolysis: ().

a.Pyruvate is reduced to lactic acid.

b.It enters the mitochondria for oxidation through the phosphoglycerol shuttle system.

c.It enters the mitochondria for oxidation through the apple stuffy acid shuttle system.

Phosphoglyceric acid is reduced to 3-glycerol phosphate.

Correct Answer: Reduction of propionecta to lactic acid.