Why mothers and babies do not reject different blood types

Although the fetus depends on the mother's nutrition in the mother's body, there is a "placental barrier" between the mother and the fetus, which can protect the blood of the mother and baby from "intermingling". However, there are still a small number of baby red blood cells that infiltrate the maternal circulation, resulting in the production of antibodies, and a small amount of the mother's blood will enter the fetus. After the child is born, the antibody-laden blood from the mother in the baby's body will be metabolized for a certain period of time, and the child will soon return to normal.

The blood of the baby and the mother does not dissolve at all. The placental barrier, also known as the placental membrane, is a structure through which fetal blood and maternal blood pass through the placenta for material exchange, and is composed of syncytiozoites, cytotrophozoites and basal membranes, thin layers of villous connective tissue and capillary basal membrane and endothelium. Later in development, because the cytotrophoblast disappears in many parts and the syncytiotrophoblast is only a thin layer of cytoplasm in some parts, the placental membrane becomes thinner, which is more conducive to material exchange.

Sometimes it can also affect the mother when the mother is type O and the child is not, especially when the second child or ......Fetus, alas, it's better to give birth to only one!!

The placental barrier will protect the vast majority of children, but it is still problematic for Rh-mothers to give birth to a second Rh+ child, but now the hospital can **.

1. Mother-infant blood group incompatibility mainly refers to the inconsistency of the blood type of mother and baby, which begins to destroy the red blood cells in the fetal blood in the womb, and thus affects the fetus.

2 The cause of this disease is because the fetus inherits antigens from the father that the mother does not have. This substance passes through pregnancy, allowing antigens to enter the mother's body. As a result, Ju Huipi's mother produced antibodies against this antigen.

This antibody will then enter the blood circulation of the fetus through the placenta, causing immune hemolysis of the fetus. The disease has no effect on the mother, but on the fetus, it can cause severe anemia, kernicterus, and even death. Hemolysis is more common in the second child.

3. Maternal and infant blood group incompatibility is divided into ABO blood group incompatibility and RH blood group incompatibility.

ABO incompatibility: A pregnant woman with blood type O gives birth to a fetus with positive blood type A or B.

Rh incompatibility: Refers to the birth of a fetus with rh-negative blood in a pregnant woman with rh-positive blood.

Both of these conditions can cause hemolysis, but the latter is mostly more severe.

41. Pregnant women with blood type O and their spouses are type A, B or AB.

2. Pregnant women with type O blood were found to have a high anti-A(B)IgG titer. (>1:64) 3. Those who have had a spontaneous abortion, or the first child has shown symptoms of jaundice.

4. In the B ultrasound examination, the fetus ** and liver and spleen swelling can be clearly observed.

Pregnant women should have their blood type tested before giving birth, mainly because there is a blood group incompatibility between the mother and the fetus. In this case, the red blood cells in the fetal blood are destroyed, causing various changes, such as miscarriage, premature birth, intrauterine death of the fetus, or neonatal hemolysis, which is called mother-child incompatibility.

ABO blood group incompatibility: the pregnant woman's blood type is O, the husband's blood type is A, B or AB, when the fetus's blood type is A or B, it is ABO mother and child blood group incompatibility, which is more common in China. However, this blood type is not suitable for mild disease, and the probability of newborn jaundice is very small, and the harm is less.

Many expectant mothers with blood type O will have some worries, how likely is neonatal hemolysis? In fact, mother-child incompatibility does not necessarily lead to hemolysis, the incidence of ABO blood group incompatibility is about 20%, but the actual occurrence of newborns is less than 5%. The probability and severity of neonatal hemolysis also increase with the increase of parity.

However, although ABO hemolysis mostly occurs in the second child, some of it also occurs in the first child.

It is the discord between the blood type of the mother and the father, which generally refers to a special blood type.