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Purine. purine) is a substance found in the body, mainly in the form of purine nucleotides, which are used as energy**, metabolic regulation and composition of coenzymes.
and so on. Purine is an organic compound, molecular formula C5H4N4, colorless crystal, purine oxidation in the human body and becomes uric acid, too high uric acid in the human body will cause gout.
The purine content of seafood and animal meat is relatively high, so in addition to using drugs for patients with gout (drugs for treating gout are generally damaging to the kidneys), it is more important to pay attention to avoid eating at ordinary times.
After a series of metabolic changes, the final product (2,6,8-trioxoprine) formed by purine (purine, also known as purine) is also called uric acid. The ** of purines is divided into endogenous purines, and 80% of them come from nucleic acids.
Oxidative decomposition, exogenous purines mainly come from food intake, accounting for 20% of the total purines, uric acid has no physiological function in the human body, under normal circumstances, uric acid produced in the body, 2 3 is excreted by the kidneys, and the remaining 1 3 is excreted from the intestines.
Uric acid is constantly produced and excreted in the body, so it maintains a certain concentration in the blood. The amount of uric acid per liter of blood in a normal person is less than millimole liters for men and no more than millimolar liters for women. In the process of purine synthesis and decomposition, there are a variety of enzymes involved, due to the congenital abnormality of enzymes or some unspecified factors, metabolism disorders, so that the synthesis of uric acid increases or decreases excretion, and the result can cause hyperuricemia.
When blood uric acid. When the concentration is too high, uric acid is deposited in the joints and soft tissues in the form of sodium salt.
In the cartilage and kidneys, it causes foreign body inflammation in the tissues, which is the bane of gout. Gout, in turn, can cause swollen joints.
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Xanthine is a product of the purine degradation pathway and is converted to uric acid by xanthine oxidase.
Uric acid is the end product of purine metabolism. If there is an increase in the synthesis or metabolism of purines (especially hypoxanthines), the uric acid produced in the body increases, and the excess uric acid is deposited in the joints and surrounding tissues, kidneys and subcutaneous connective tissues, which can cause gout attacks.
Gout is a disease caused by a purinant metabolic disorder, and its clinical manifestations are hyperuricemia and the resulting acute or chronic gouty arthritis.
Causes of purinant metabolic disorders may include:
1.Enzymes involved in purine synthesis and catabolism are defective, resulting in increased uric acid production.
2.Decreased uric acid excretion is due to decreased renal function or increased uric acid reabsorption due to drug-induced and decreased tubular secretion of uric acid.
Since half of the uric acid in the human blood comes from the synthesis of the body and half from the high-protein and high-purine diet, gout should be consumed as little as possible to reduce the production of uric acid in the body. For example, foods with less purines are: cereals and vegetables; Foods high in purines:
High-protein meats (especially offal), soy products, etc.
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The purine value of rice wine is high, hyperuricemia can not be drunk, hyperuricemia is because of too much uric acid in the blood, and foods with high purine value can lead to acute gout and acute synovial fluid attacks, which will develop into chronic nephritis and kidney stones in the long run, which is very painful. Therefore, for this kind of people, foods with high purine values are inedible.
Rice wine and beer have the highest purine value of all alcoholic beverages, especially beer, which has a purine value of 5-6 mg per 100 ml, while rice wine has a purine value of up to mg per 100 ml. Although the purine value of rice wine is higher in terms of unit, due to the relationship between alcohol content, the degree of beer is lower, and drinking beer will be drunk in large quantities, resulting in a cumulative increase in purine value.
Patients with hyperuricemia are not recommended to drink alcohol, especially rice wine, not only because the ethanol in the wine can increase lactate in the body, but also because the purine value can cause an increase in uric acid in the blood, which will increase the probability of acute attack of gout. Therefore, if you are a patient with hyperuricemia and cannot consume rice wine, avoiding eloquence can stabilize the condition.
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1. Purines are components of DNA and RNA in living organisms, and high purines generally refer to foods that contain more purines.
2. The metabolite of purine is uric acid, and a high-purine diet is easy to cause hyperuricemia, if uric acid forms crystals around the joints, it will cause gout, and if the uric acid in the urine is too high to form crystals, it will cause kidney stones, ureteral stones, etc., and in severe cases, it will cause kidney damage.
3. Common high-purine foods include: marine fish, shellfish, shrimp, mushrooms, animal brain tissue, offal and broth.
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Purine is a substance in the body, mainly in the form of purine nucleotides, which plays a very important role in energy, metabolic regulation and composition of coenzymes.
High levels of purines in the body can lead to hyperuricemia, and chronic patients can lead to gout, manifested by acute arthritis, fever, gouty stones in the joints, and so on.
Methods of inhibiting excessive purines:
1.Limit high-purine foods. It is forbidden to eat foods high in purines, such as liver, loin, pancreas, sardines, anchovies, gills, mackerel, gravy, prawns, broth, lentils, dried beans.
2.Limit fat intake.
3.Feed the right amount of carbohydrates.
4.Provide adequate vitamins, water, and alkaline foods.
5.Chronic gout or gout in remission, should be given a balanced diet, can be appropriately relaxed purine intake restrictions, free to choose less purine food, the daily content of purines should be within 75 mg, maintain the ideal weight, lean meat boiled to remove the soup and eggs and milk alternately to prevent excessive hunger, usually should pay attention to drink more water, less salt and soy sauce.
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Protein itself does not contain purines, but proteins are degraded into amino acids, and some metabolic intermediates will be produced in the process of amino acid redegradation, and there are enzymes in the human body that can convert these intermediates into hypoxanthines.
Purines are a general term for a large group of organic compounds. The basic structure of DNA is deoxyribose plus bases. Among them, there are 2 types of bases, purines and pyrimidines. There are 2 types of purines in DNA, guanine and adenine.
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Low-purine foods: whole grains, eggs, milk, fruits, vegetables; Medium-purine foods: Xiangkuan meat, beans, seafood; High-purine foods: bean sprouts, soybean sprouts, asparagus, shiitake mushrooms, seaweed, animal offal, fish.
Purines are the main components that make up the nucleus, the more nuclei there are, the more purines, and most of the low-purine foods are nutrients, such as grains, the main thing is starch, the main thing is sugar, and the main thing in vegetables is crude fiber.
In high-purine foods, there are many more cell structures than others, so purines are also high.
If you are looking for gout-related, remember to be sure to eat less high-purine foods, beer has low-purine types, you can drink it.
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Purine food refers to the organic compounds that contain high-purity purines.
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About what does high purine mean. Uric acid is produced by purine metabolism. In the body, a compound called purine is produced after the food eaten and the cells in the body are metabolized and broken down.
If too much purine is generated, the substance in the body is higher than the normal value, which is called high purine. Purine substances are also found in food. High-purine foods.
That is, more than 100mg of purines per 100 grams of food. Purines are further broken down to form uric acid.
Blue Chrysanthemum. Tea can effectively reduce uric acid, and the blue chrysanthemum, blue chrysanthemum acid and blue chrysanthemum in the blue chrysanthemum can be improved and cleaned up under the coordination of the abdomen and brain, especially the help obtained by the liver and kidneys is not achieved by other substances. For example, the fat accumulation of the liver, blue chrysanthemum can quickly convert it into energy and act on the whole body, reduce fat accumulation, and prevent fatty liver.
The help to the kidneys is concentrated in the decongestion and diuresis, people have a healthy kidney, and the metabolism has a complete cycle.
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Too high purines can cause gout, causing purine metabolism disorders in the human body and causing abnormal uric acid secretion in the body, and too high uric acid will become a toxin that the human body cannot metabolize and cause gout. Too high purines in the human body will cause joint deformation and swelling, purines in the human body are mainly transported to various joints through the blood, too high purines in the body will cause different degrees of damage to the joints, too high purines can also cause kidney damage, purines in the human body are mainly metabolized by the kidneys, and regular consumption of foods with too high purine content will lead to purine retention in the body in the kidneys and cause kidney damage, and even lead to increased blood pressure. If the purines in the human body are too high, you should quit smoking, stop drinking, avoid eating seafood and other high-purine foods, pay attention to eating habits and work and rest time, avoid fatigue, and exercise appropriately.
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