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Cellular senescence is the proliferation of cells over time in the process of performing vital activities.
Changes with a gradual decline in differentiation ability and physiological function. The life course of a cell goes through several stages: undifferentiated, differentiated, growing, maturing, aging, and dying. Aging and dying cells are taken by the body's immune system.
At the same time, new cells are constantly being generated from the corresponding tissues and organs to compensate for the aging and death of cells.
Apoptosis. Different from cell necrosis, apoptosis is not a passive process, but an active process, which involves the activation, expression and regulation of a series of genes.
Significance of senescence and apoptosis of cells
Apoptosis and cell proliferation are both basic phenomena of life and basic measures to maintain the dynamic balance of cell number in the body. In the embryonic development stage, the redundant and mission-completed cells are removed through apoptosis, which ensures the normal development of the embryo; In adulthood, senescent and diseased cells are removed through apoptosis, ensuring the health of the body.
The basis of body aging is the aging of the cells that make up the body at the level of the whole, system or organ, but it does not mean that all the cells that make up the body have undergone aging. Cell senescence and death and the growth and replacement of new cells in normal life activities are the inevitable laws of metabolism, and they also avoid tissue structure.
Degeneration and the accumulation of senescent cells allow the body to delay overall aging.
The above content refers to Encyclopedia - Cellular Senescence.
The above content refers to Encyclopedia - Apoptosis.
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Summary. I used to be a national paper candidate, and according to the situation of the national paper, cell aging and death are one of the test points of the college entrance examination.
I used to be a national paper candidate, and according to the situation of the national paper, cell aging and death are one of the test points of the college entrance examination.
However, it is not the difficulty of biology, it mainly lies in memory and comprehension, and there is no requirement for comprehensive application.
It is only necessary to understand the causes of cell senescence and death, to be able to distinguish the difference between individual senescence and cellular senescence, and to know the two theories of aging, i.e., 1Telomere Theory 2The two theories of free radicals are sufficient to know the basic concepts, family rolling, and meaning.
The examination of this part of the college entrance examination biology is mainly based on the understanding of memory and conceptual reasons.
It does not examine comprehensive applications and calculations like genetic questions.
I wish you progress in your studies and success in the college entrance examination.
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Apoptosis is the autonomous, orderly death of cells under genetic control. It involves the activation, expression and regulation of a series of genes, and is a local cell death process that organisms actively strive for in order to better adapt to the living environment.
Normal organisms have to go through a process of birth, growth, maturity, aging, and death. Therefore, cell decay is the inevitable result of normal life activities (cell decay is the process of DNA telomere shortening). There is no necessary relationship between apoptosis and cell decay.
Apoptosis is a normal physiological activity that does not lead to the death of biological organisms.
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In the process of life, the human body always has some cells that continue to age and die, and at the same time, there are cells that proliferate to replace them, after the human body is born, the growth of life, development, maturity, aging and death are the inevitable laws of the life process. The aging of the body is the result of cellular senescence, but the aging and death of the body is different from the aging and death of cells, and the fall of the body does not mean that all cells age at the same time, and the aging of cells is closely related to the aging of the body. Cell senescence and death are the basic laws of cell life activities, in the process of cell falling, a series of changes will occur in the cell structure, there are two forms of cell death, namely necrotizing death and natural apoptosis, which are two completely different processes.
Necrotizing death can cause an inflammatory response, and natural apoptosis can cause an inflammatory response, which is of great significance for maintaining cell metabolism in living organisms.
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Some cells are restored in the body.
If you use it for too long, the metabolic level decreases, which is not good for the body. Entering programmed aging and death helps to conserve nutrients in the body. Just like plants have to be pruned, some plants have too many leaves, which are occluded, and the lower leaves cannot photosynthesize, but they have to respire to consume nutrients.
Proper pruning at this time is beneficial for the growth of the whole plant.
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Apoptosis is a copy of programmed death, which occurs when certain conditions are reached, such as genetic settings, such as tadpoles that lose their tails are apoptosis.
Cellular senescence is the result of a combination of factors, both internal and external. It's complicated.
Your second question can be combined with the above two questions. The same can be said in the absence of rigor. But cells don't die first and then age, hehe.
Big Science team.
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Senescence first, followed by apoptosis, apoptosis is the normal death of cells.
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Cell differentiation, cell proliferation, and apoptosis all have positive significance.
Cell differentiation: increase the type of cells, specialize in cell function, and proliferate: increase the number of cells, which is related to human growth, and replenishes senescent, damaged, and apoptosis cells together with cell differentiation.
Apoptosis: Programmed death in which genetically controlled cells automatically end their lives in order to maintain a stable internal environment. Such as apoptosis of interdigital cells.
Apoptosis is different from cell necrosis, apoptosis is not a passive process, but an active process, which involves the activation, expression and regulation of a series of genes.
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