Describe the oxidation process of stearic acid and how many molecules of ATP are generated

Stearic acid. oxidation in the cytoplasm.

and mitochondria. The oxidation process can be divided into four stages.

Activation of stearic acid: stearic acid + ATP + HSCOA stearoyl CoA + AMP + PPI (catalyzed by liparoyl Coa synthetase).

Stearoyl enters the mitochondria: it enters the mitochondria by the action of carnitine and carnitine lipacyltransferase. Carnitine lipacyltransferase is a rate-limiting enzyme for fatty acid oxidation.

-oxidation of the stearoyl group: -carbon atom in the lipamil group.

The continuous reaction process of dehydrogenation, water addition, rehydrogenation, and sulfur hydrolysis is called -oxidation of the lipid acyl group. Each of the above four steps produces 1 molecule of acetylCoA, FADH2, Nadh+H+, and the fatty acyl Coa is reduced by two carbon atoms.

Acetyl Coa enters TAC and oxidative phosphorylation.

Thorough oxidative decomposition.

1 molecule of stearic acid oxidation after 8 times of oxidation to generate 9 molecules of acetylCoA, into TAC and oxidative phosphorylation to produce ATP is (molecular ATP, minus the ATP consumed by stearic acid activation, net generation of 120 molecules of ATP.

1mol stearic acid (

Carbon-saturated acid) is oxidized (dehydrogenation, hydration, rehydrogenation, and sulfur hydrolysis) 8 times to produce 9mol of acetyl-CoA

1 oxidation yields 4molatp, and 1mol acetyl-CoA is thoroughly oxidized by the tricarboxylic acid cycle to produce 10molatp.

1mol of stearic acid is completely oxidized and net generated.

The ATP number is:

8 4 9 10 2 (activation consumption) 120mol

Calculation process: 1 mole of palmitic acid containing 16 carbons is completely oxidized to produce 8 acetyl-CoA, 1 mole of acetyl-CoA enters the tricarboxylic acid cycle to produce 10 ATP, 8 produce a total of 80, oxidation has two dehydrogenations, one to monovalent FAD, one to monovalent NAD, and the two are obtained by post-hydrogen oxidative phosphorylation;

AND ATP are produced separately, so a single dehydrogenation produces 4 ATP, and 1 mole of palmitic acid containing 16 carbons is completely oxidized 7 times, resulting in a total of 28 ATP.

Thus, 1 mole of palmitic acid containing 16 carbons is thoroughly oxidized to produce 108 ATP. However, the activation phase of fatty acids consumes two high-energy phosphate bonds in 1 molecule of ATP, which is equivalent to 2 molecules of ATP, so it is necessary to subtract the consumption of this process, and finally produce a net of 106 ATP.

1mol stearic acid (

18 carbon saturated acid) after 8 times of oxidation (dehydrogenation, hydration, rehydrogenation, sulfur hydrolysis) to produce 9mol of acetyl-CoA

1 time of oxygen cracking grinding produces 4molatp, and 1mol acetyl-CoA is cycled by tricarboxylic acid.

Thorough oxidation yields 10molatp, then 1mol of stearic acid is completely oxidized to produce ATP

8 4 9 10 2 (activation consumption) 120mol

Activation consumes two ATPs

Each round of oxidation produces one acetyl-CoA, one Fadh2, and one NaDH

Each acetyl-CoA enters the tricarboxylic acid cycle to produce 3 NADH and one FADH2, which are then phosphorylated horizontally to give an ATP

Stearic acid has a total of 18 C, and after 8 rounds of oxidation, 9 acetyl coa

A total of 7 ATPs (minus the first 2 consumption), 17 FADH2 and 35 NADH

In the respiratory chain, 2 ATPs are generated with one FADH2 and 3 ATPs from one NADH, then the total is:

7 + 17 * 2 + 35 * 3 = 146 ATP

According to the new algorithm, one FADH2 generates an ATP, and one NADH generates an ATP, then the total is: 7+17* ATP

1mol stearic acid (

Thorough oxidation can produce 146MolatP, a molecule of stearic acid can produce 8 molecules of FADH molecule NADH and 9 molecules of acetyl Coa after 8 times of oxidation, and the chemical formula of stearic acid is C18H36O2.

The molecular weight of stearic acid is, is a chemical compound, i.e., octadecanoic acid. It is produced by hydrolysis of oils and fats, mainly used in the production of stearate. Stearic acid is slightly soluble in cold water, soluble in alcohol, acetone.

Soluble in benzene, chloroform, carbon tetrachloride.

Carbon disulfide, amyl acetate and toluene, etc.

106, calculation process: 1mol palmitic acid (containing 16 carbons) is completely oxidized to produce 8 acetyl-Coenzyme acetyl-CoA enters the tricarboxylic acid cycle to produce 10 ATP, 8 produce a total of 80, a B-oxidation has two dehydrogenations, one to FAD+, one to NAD+, the two get hydrogen after oxidation phosphorylation, respectively, ATP, so a time down to produce 4 ATP, 1mol palmitic acid (containing 16 carbons) to completely oxidize to go through 7 times of B-oxidation, A total of 28 ATPs are generatedThus, 1 mol of palmitic acid (containing 16 carbons) is thoroughly oxidized to produce 108 ATP

However, the activation stage of fatty acids consumes two high-energy phosphate bonds in 1 molecule of ATP, which is equivalent to 2 molecules of ATP, so it is necessary to subtract the consumption of this process, and finally produce 106 net ones.

Process: Dehydrogenation.

Add water. Re-shoot type dehydrogenation.

Sulfur hydrolysis. Calculation:

Fatty acid activation to acetyl CoA consumes 2 molecules of ATP

Qi contains 1 molecule of 20C saturated fatty acids.

Oxidation requires 9 cycles to produce 10 molecules of acetyl CoA, 9 molecules of FADH2 and 9 molecules of NADH

The H10 molecule acetylCoA enters the TAC to generate 10 12 = 120 molecules, the ATP9 molecule, and the molecule FADH2 enters the succinic acid.

Oxidative attack guesses that the respiratory chain generates 9 2 = 18 molecules of ATP

9 molecules NADH

H enters the NADH oxidative respiratory chain to generate 9 3 = 27 molecules ATP net generation of 120

27-2 = 165 molecular ATP

Briefly describe the -oxidation process of Shitan fatty acids, and calculate the net ATP produced by the thorough oxidation and decomposition of a molecule of eicosanated lipid acid

Number of molecules.