What is the mechanism of action of inactivated probiotic preparations?

The effect is definitely there.

In the inactivated probiotics experiment, researchers in the laboratory through heat inactivation of Lactobacillus plantarum to inhibit tumor cells in rats with daily adage, the results found that after transplanting tumor cells, the effect of inhibiting the growth of tumor cells is the most obvious. Experiments have shown that the effect of using inactivated Lactobacillus plantarum is still obvious.

The probiotics added to the toothpaste are lactobacilli, which has been proven in the laboratory to be effective by adding inactivated probiotics to the toothpaste, and compared with live bacteria, inactivated probiotics are safer and not limited by the amount of bacteria.

A live probiotic is a probiotic whose body is alive and can be detected by the dilution plate counting method, and the unit is "CFU g". It can inhibit the growth of other harmful microorganisms through its metabolites, such as lactic acid, organic acids, etc., and at the same time, it can compete with harmful bacteria to bind to the adsorption sites on intestinal epithelial cells, which has the effects of regulating intestinal ecological balance, activating immune cells, and improving immunity. It is used in food, health care products, solid beverages and other fields.

Inactivated probiotics are treated by a special process in the processing process, so that they can be inactivated on the premise of ensuring the morphology of intact cells, and can only be detected by hemocytometer"g"。It can also compete with harmful bacteria to bind to adsorption sites on intestinal epithelial cells, and its products can also inhibit the growth of pathostatic bacteria. Its application field is mainly in daily chemicals, such as a probiotic toothpaste produced by Jiangsu Weikang, which is a toothpaste made of inactivated probiotics, which has the effect of refreshing breath and preventing tooth decay.

Inactivation is of course inactive. Nowadays, probiotic preparations are not all live bacteria, and some probiotics are inactivated by specific means to become dead bacteria, which is inactivated probiotics. However, most of the ones available on the market are active.

For example, the DuPont Danisco probiotic powder that I have been using is a live probiotic, this dry powder preparation is more stable than the liquid live bacteria count, and it is also very convenient to eat!

Live probiotics are a kind of microorganisms, due to the different properties and metabolism methods of various microorganisms, and are divided into beneficial microorganisms and harmful microorganisms, harmful microorganisms oxidize organic substances, resulting in food deterioration, mold, and rot of utensils

There are many strains used in the production of probiotic preparations, mainly including the following three categories.

1) Lactic acid bacteria are the main members of the intestinal flora of a variety of animals, grow under microaerophilic or anaerobic conditions, secrete lactic acid and short-chain fatty acids, synthesize B vitamins, have strong acid resistance, can tolerate low pH value in the stomach, inhibit the colonization, adsorption and reproduction of Escherichia coli and Salmonella in the intestine, neutralize toxic products, inhibit the synthesis of ammonia and amines, and enhance immunity.

2) Bacillus is an aerobic bacterium, with protease, lipase, amylase activities, rich in a variety of amino acids, this kind of preparation mostly exists in a spore state, does not proliferate in the intestinal environment, only rapidly develops and transforms into vegetative cells in the upper part of the intestine. The main applications are Bacillus licheniformis, Bacillus brevis, Bacillus subtilis, Bacillus cereus, etc.

3) Yeast-like yeasts are only sporadically present in the microbial community of the gastrointestinal tract of animals. The proliferation of yeast in the gastrointestinal tract can effectively improve the gastrointestinal environment and bacterial structure, promote the reproduction and vitality of beneficial bacteria such as lactic acid bacteria, and improve the decomposition and utilization of food nutrients by the gastrointestinal tract, thereby improving food utilization rate and animal production function. At the same time, it can effectively inhibit the reproduction of pathogenic microorganisms, participate in the survival competition of pathogenic microorganisms, enhance the body's immunity and disease resistance, and play a beneficial role in preventing digestive diseases.

The main applications are Saccharomyces cerevisiae and petroleum yeast.

The strains of probiotic preparations used vary from country to country. In 1994, China's Ministry of Agriculture approved the use of microbial strains such as Bacillus cereus, Bacillus subtilis, Streptococcus faecalis, Bifidobacterium, Lactobacillus, Streptococcus lactis, etc. According to the Ministry of Health's "Regulations on the Evaluation of Probiotic Health Foods", the probiotic strains that can be used for health foods are:

Bifidobacterium bifidum, Bifidobacterium longum, Bifidobacterium breve, Bifidobacterium youth, Bifidobacterium infantis, Lactobacillus delbruecki's subsp. bulgaric, Lactobacillus acidophilus, Lactobacillus casei subsp. casei, Streptococcus thermophilus.

1.Respiratory system: probiotics should be supplemented for colds and fevers; 2.Digestive system: probiotics should be supplemented for constipation and diarrhea; 3.Urinary system: ** The problem is to supplement probiotics; 4.Organs: Allergies should be supplemented with probiotics.

1.Respiratory system: probiotics should be supplemented for colds and fevers; 2.Digestive system: probiotics should be supplemented for constipation and diarrhea; 3.Urinary system: ** The problem is to supplement probiotics; 4.Organs: Allergies should be supplemented with probiotics.

Take a break.