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At present, there are two types of drugs that reduce uric acid levels, one is drugs that promote uric acid excretion, such as benzbromarone, probenecid, flavacetone, etc. 2. Drugs that inhibit the production of uric acid, such as allopurinol, febuxostat, and uric acid-lowering drugs are mainly used for hyperuricemia. However, which type of drug is better, clinical should choose different uric acid-lowering drugs according to the specific condition of the patient and the specific situation of his or her renal function.
The principles to be followed when choosing urate-lowering drugs, such as normal or mildly impaired renal function, reduced or normal uric acid excretion, drugs that promote uric acid excretion, such as benzbromarone, probenecid, flavacetone, etc., can be used. If there is moderate or higher renal impairment and excessive uric acid excretion, uric acid excretion drugs can cause urate stones and aggravate kidney damage, so drugs that inhibit uric acid production should be chosen. For example, allopurinol, febuxostat.
In short, in uric acid**, it is necessary to pay attention to the basic principles of medication. Whether you choose a drug that excretes uric acid or a drug that inhibits uric acid production in the blood, the dose should be started at a low dose and gradually increased. The choice of drug depends on the specific situation of the patient.
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Some friends began to worry when they found that they were found to have high uric acid, and they kept thinking about it in their hearts, for fear that they would get sick What to do if they have high uric acid in their minds? In fact, don't worry too much when you find that your uric acid is high, you can often drink maple grass tea while receiving a doctor**, and follow the following requirements. Eat more vegetarian 1 But not all vegetarian foods should be eaten more, eat more purple eggplant, Shanghai green, lettuce, lotus white.
Avoid spinach and then eat less or no legumes. Eat more fruits, as well as lemons, etc., all kinds of fruits are composed of carbohydrates, so that the body has a positive effect on alkaline, especially eating more cherries can lower uric acid. Control the intake of a low-protein diet 2 We should control the intake of a low-protein diet every day, and gout patients should be given grams of protein per kilogram, and the total amount of protein per day should be controlled at about 40 grams, and the intake of fish and legumes should be appropriately limited.
Prohibit the consumption of foods with high purine content 3 It is important to prohibit the consumption of foods with high purine content, such as fresh fish and seafood with animal offal. Patients with gout should eat more foods with low purine content, such as milk, eggs, bread, cucumbers, tomatoes, etc., to reduce the entry of exogenous purines into the body, reduce the blood uric acid level and control the total calories. Mainly high-carbohydrate foods 4 In addition, high-carbohydrate foods should be the mainstay, and the main components of rice, noodles and cereals are carbohydrates, so gout patients should mainly eat these foods on weekdays to ensure calories**.
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People with high uric acid may take drugs that promote uric acid excretion or drugs that inhibit uric acid production. Hyperuricemia is closely related to the poor prognosis of blood vessels, heart, and kidneys, and is also the pathophysiological basis of gout. Hyperuricemia can choose drugs that inhibit uric acid synthesis, such as allopurinol or even febuxostat, which are drugs that inhibit uric acid synthesis.
Of course, the specific type and dosage should be reasonably selected under the guidance of the doctor to ensure efficacy and safety.
At the same time, nearly 90% of patients with high uric acid have abnormal uric acid excretion, and drugs that promote uric acid excretion can also be selected, including Ligalizian, which should drink more water after eating, which can help the excretion of uric acid. Although hyperuricemia requires medication to help, it is also important to avoid eating a high-purine diet, such as animal offal, various soups, such as fruit soup, vegetable soup, chicken soup, duck soup, hot pot soup, and avoid eating all kinds of seafood.
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Febuxostat: Febuxostat and allopurinol are both inhibitors of xanthine oxidase, but febuxostat is not recommended for patients with only hyperuricemia and ** wind;
Allopurinol: In the process of application, it is necessary to pay attention to the occurrence of rash, leukopenia, liver damage, etc., febuxostat and allopurinol are mainly used to inhibit the production of uric acid;
Benbromarone: It is mostly used for patients with reduced uric acid excretion, and the patient's uric acid excretion can be judged by 24-hour uric acid, and if uric acid excretion is reduced, and there are no kidney stones or obstructive nephropathy, benzbromarone can be selected. Regardless of which urate-lowering drug is chosen, it is necessary to intervene in lifestyle and reduce high purine.
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1. Eat more high-potassium foods.
Such as bananas, broccoli, celery, etc. Potassium reduces uric acid precipitation and helps to excrete uric acid from the body. Eat plenty of alkaline foods, such as kelp, cabbage, celery, cucumbers, apples, tomatoes and other sparse fruits.
2. Eat more foods that promote qi and blood.
**High uric acid often uses mulberry parasitism (one person's portion is five yuan) to make sugar water, but do not put eggs, you can add lotus seeds.
3. Eat more kidney-strengthening foods.
Traditional Chinese medicine believes that foods that strengthen the kidneys can help excrete uric acid, and can be used on weekdays to drink decoction water with the formula of Rehmannia Rehmannia, Rehmannia, Cornus officinalis, Yam, Zexiao, Danpi and Poria cocos, so as to nourish yin and nourish the kidney.
4. Eat more alkaline foods.
Winter melon is diuretic and anti-inflammatory, clears heat and detoxifies, and can also sober up. Watermelon, with diuretic element base, tarmonthin, makes salt smoothly excreted with urine.
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In general, if you take drugs that inhibit uric acid production or promote uric acid excretion, the effect will be better.
1. Drugs that inhibit uric acid production: the more common drugs are allopurinol, febuxostat and so on. Both drugs are indicated for most patients with high uric acid, but some patients may have an allergic reaction to allopurinol, so monitoring is recommended before taking this drug.
2. Drugs to promote uric acid excretion: the more common ones are benzbromarone and benziododarone, etc., and some patients are more suitable for probenecid, etc., it is recommended to take specific drugs, we must combine their own physical conditions and doctor's instructions to judge, if there are kidney stones, it is not suitable to use drugs to promote uric acid excretion, which may aggravate kidney stones.
In addition, patients also need to adjust their diet, exercise moderately, lose weight, and minimize the intake of high-purine foods while taking drugs**. Patients with high uric acid can take corresponding drugs for uric acid lowering**, such as benzbromarone tablets, febuxostat tablets, etc. In addition to taking these drugs for uric acid lowering**, it is also necessary to achieve the purpose of reducing uric acid levels through strict dietary control, patients can not eat foods containing too high purines, such as lobster, fat intestines, cerebral spinal cord, etc., and absolutely can not drink alcohol.
In addition, patients with significant joint pain symptoms need to take medication to relieve pain.
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The normal physiological saturation of uric acid in the human body, in the case of a body temperature of 37, is about 420 mol l, if it exceeds 420 mol l, hyperuricemia can be diagnosed. Whether hyperuricemia is needed or not is controversial, and opinions have changed. In the past, it was thought that as long as there was no gout, ** was not needed, but now it is believed that if the uric acid level is too high, even if there is no gout, ** is needed.
Because hyperuricemia itself is an independent risk factor for many diseases. Uric acid-lowering drugs are two major aspects: 1. Inhibition of uric acid-producing drugs, such as allopurinol, febuxostat, etc.; 2. Drugs that promote uric acid excretion, like benzbromarone.
Different drug choices are not the same for the population, such as benzbromarone is very safe in Asian races, as long as the patient has kidney function and no obvious kidney stones, they can choose. Febuxostat, like allopurinol, is an inhibitor of uric acid production, and the safety is relatively newer and safer. Some people will be allergic or hurt their liver when they eat allopurinol, so there will be relatively fewer people who choose allopurinol.
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1. Atractylodes plantain formula: The main effect of this prescription is to reduce uric acid, clear heat and diuresis, dissipate wind and heat dissipation, and also relieve the symptoms of joint pain caused by gout, the main ingredients include Atractylodes atractylodes, cork, hyssop, psyllium, coix seed, and hyssop. When using, you can take an appropriate amount of these drugs and put them into a tea pot, add an appropriate amount of water and boil them over slow heat, and then take them off while they are warm after the flavor comes out, and patients with high uric acid can drink them several times a day.
2. Dandelion Root Poria Cocos Drink: The main ingredients of this uric acid-lowering Chinese medicine prescription are dandelion and Poria cocos, when using, take an appropriate amount of these two drugs and put them in a casserole to boil water, and take the juice while hot. Traditional Chinese medicine believes that dandelion is a Chinese herbal medicine with diuretic, anti-inflammatory and other effects, while Poria cocos has the effect of unfavorable urination and edema and other symptoms.
The combination of the two can play a very good role in clearing heat and detoxifying, diuretic and dampness, edema, and uric acid reduction.
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If the uric acid is only high, do not take medicine, generally you can use chicory light bamboo leaf tea to make tea, which is conducive to the excretion of uric acid and prevents the deposition of urate crystals, so as to reduce uric acid and prevent or reduce gout attacks. Among them, chrysanthemum and light bamboo leaves are commonly used in clinical heat clearing drugs, light bamboo leaves treat gout: normal people try to decoction with 10g of the product, the diuretic effect is weak, but it can increase the excretion of chloride in the urine.
Its diuretic effect is weaker than that of Mutong and Zhu Ling, but its excretion of chloride in urine is stronger than that of Zhu Ling. Promotes the excretion of urate from the urine. Uric acid above normal is generally considered to be the possibility of gout.
It is a metabolic disease. If left uncontrolled, it can lead to problems in all systems throughout the body. **Included:
Diet**Diets containing high purines should be avoided. Animal offal, bone marrow, seafood, etc. are the most abundant in purines; Fish and shrimp, meat, peas, spinach, etc. also contain certain purines; Fruits, vegetables, milk, eggs, etc. are purine-free. It is advisable to drink plenty of water to facilitate the excretion of blood uric acid from the kidneys.
In terms of drugs, drugs that lower blood uric acid, such as allopurinol, can be used.
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In modern society, due to changes in dietary structure, there are many people with elevated uric acid, some are asymptomatic, and some have gout. So how high is uric acid, and you need to start taking uric acid-lowering drugs, clinical pharmacists will explain clearly to you in 2 situations, as well as what are the commonly used first-line uric acid-lowering drugs.
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High uric acid, soak in water with Qingming vegetables, and the effect is very good.
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If the uric acid is high, first of all, you should control your diet in the early stage, don't eat some seafood or foods with high uric acid, such as animal offal, these are beer, or some alcoholic things, try not to eat, you should quit smoking and drinking, and insist on exercising, so as to help reduce the medicinal acid, if it really doesn't work, take a little medicine, but the drug must be used under the guidance of a doctor.
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aWe reduce uric acid through two channels, one is to reduce the body's uric acid production, and the other is to accelerate the excretion of uric acid from the urine. We reduce uric acid through two channels, one is to reduce the body's uric acid production, and the other is to accelerate the excretion of uric acid from the urine. First of all, the main drugs that inhibit the body's production of excessive uric acid are allopurinol and febuxostat, which are mainly used to prevent it from producing excessive uric acid by inhibiting the enzyme synthesis from purine to uric acid.
The main problem of this kind of drug is to produce rashes and allergies, especially like allopurinol, in some people, it will produce a kind of exfoliative dermatitis called fatal, so everyone must be careful. Like febuxostat, there have been some reports of rashes, allergies, or liver damage in some people. On the other hand, we promote the excretion of uric acid, first of all, to promote the excretion of uric acid, we must drink more water, if the liver function, kidney function and heart function are normal, the daily water intake should reach at least 2,000 ml, so that the excess uric acid in the blood will be discharged.
There are two kinds of drugs that promote uric acid excretion, one is called benzbromarone, which is a new type of uric acid excretion, which mainly inhibits uric acid from the human renal tubules, and then absorbs it back to promote the excretion of uric acid from the urine. Another medicine is called probenecid, which is a drug that has been used for a relatively long time, and it is also an old drug, which is also conducive to the excretion of uric acid. In the process of excreting uric acid, we must pay attention to alkalize urine, because uric acid has a characteristic, it will form stones in an acidic environment, in this way, kidney stones will be formed in the urinary system, which has caused great damage to the kidneys.
If hyperuricemia is more severe and lasts for a long time, in some special circumstances, gout will be induced, if gout occurs, we generally choose some non-steroidal painkillers according to the severity of the patient's illness and the state of his liver and kidney function, and can also use a small dose of colchicine, or glucocorticoids.
Life uric acid tells that the level begins to show a younger trend, some common fatigue. Too much stress. Poor diet can lead to high uric acid levels. At this time, the best way is to use Depu's Zifeng herbal tea to control uric acid, and go to the relevant hospital for timely prevention and control. >>>More
It is very important for patients with high uric acid to control their diet at ordinary times, first of all, it is best to eat low-purine food, low-purine food is mainly fresh green leafy vegetables, as well as fruits and milk, these are low-purine foods, but we must pay attention to it in life, do not eat high-fat food, especially some animal offal, as well as big fish and meat.
It is better to eat more fruits and vegetables with high uric acid. Especially celery, tomatoes, and black fungus, among others. >>>More
What to do if uric acid is high.
1.People with high uric acid should eat some light food, do not often eat some animal offal food, and do not drink beer often. >>>More
If uric acid is high, you can't eat acidic foods such as yogurt and vinegar.