What are the symptoms of Parkinson s disease in the later stages?

The symptoms of Parkinson's disease are as follows:

1. Resting tremor, tremor is often the first symptom of the disease, mostly starting from the distal end of one upper limb, manifested as regular finger flexion and hallux-to-palm movement, such as a pill-like action, its frequency is 4-6Hz, the amplitude is uncertain, and the gross tremor is mostly coarse.

2. Myotonic Parkinson's disease has increased muscle tonic extravertebral muscle tone, that is, the tension of extensor and flexor muscles increases at the same time, and when the elbow joint of one wrist is passively moved, the resistance felt by the examiner is uniform, which is called lead tubular muscle rigidity.

3. Bradykinesia, bradykinesia is a special movement disorder in Parkinson's disease, patients can show a variety of slow movements, a decrease in voluntary movements, from the beginning of the movement.

4. Abnormal posture and gait, due to the stiffness of the limbs, trunk and neck muscles, it often presents a special posture, that is, the patient shows head forward tilt, trunk flexion, elbow knee flexion, wrist joint straightening, forearm adduction, hip and knee joint slightly bending, which is called flexion posture.

5. Other symptoms, due to oropharyngeal and palatine muscle movement disorders, slow speech and low tone, severe pronunciation monotonous and unclear speech, making it difficult for others to understand, and salivation.

The symptoms of Parkinson's disease in the late stage, first, with the progression of the disease, Parkinson's patients will have slow and gradual aggravation of their movements in the advanced stage, and their walking and daily life functions will be affected; The second aspect is that there will be painful symptoms, muscle twitching pain or pain in the toes and toes; The third will be the end of the drug, which may be very effective with some drugs at the beginning, but in the later stage, the duration of the drug is gradually shortened, and the effect of the drug is not obvious; There is also a change in motor symptoms with taking medicine, such as an increase in movement after half an hour to an hour after taking medicine, which is called dyskinesia; In addition, there will be some emotional problems, patients due to motor dysfunction have depression, unwilling to communicate with others, unwilling to move, constipation will be aggravated, and even some will hallucinate, some manifestations of dementia. Mood and intelligence changes are also symptoms of Parkinson's: Mood and intelligence changes are common manifestations of late Parkinson's disease.

People with Parkinson's disease can also have psychiatric symptoms, which manifest as symptoms of depression and dementia. Some patients have apathetic expressions, depressed mood, slow response, poor self-control, lack of self-confidence, pessimism and misanthropy, suspiciousness, stubbornness, fear, irritation, etc., which is one of the late symptoms of Parkinson's. Symptoms of Parkinson's disease also include intractable constipation, rarely intestinal obstruction, and dyskinesia of the esophagus, stomach and small intestine that can cause dysphagia, esophageal spasm, and gastric-esophageal reflux.

The symptoms of patients with Parkinson's disease in the middle and advanced stages mainly include limb tremors, muscle stiffness, clumsy movements, and at the same time, due to the lack of facial expressions of the patients, the mask face is presented, the speech is slurred, the tone is single, the volume is reduced, and the drooling is often drooling, which makes the patient feel indecent, and it is easy to lead to a sense of psychological inferiority complex for a long time, unwilling to participate in social activities, not going to public places, neglecting interpersonal communication, and being prone to psychological disorders and intellectual impairment for a long time, especially in patients in the advanced stage.

In addition, patients with advanced Parkinson's disease are also prone to digestive complications, mainly manifested as nutritional disorders and water and electrolyte disorders, esophageal dilation, delayed gastric emptying, and poor small intestinal motor function, so it is easy to cause constipation.

In addition, insomnia, anxiety, depression, etc. will occur during the development of the disease.

Patients with advanced Parkinson's disease present with severe disability, inability to get out of bed or live in a wheelchair, difficulty swallowing, choking on water, slurred articulation, decreased volume, monotonous, flat and unrhythmic speech, sometimes with a tendency to accelerate, and fulminant language. The tremor does not diminish or disappear with voluntary movements, but evolves into a recurrent tremor. Limb pain, intractable constipation, loss of smell, etc.

The main symptoms of advanced Parkinson's disease include resting tremor, muscle rigidity, bradykinesia, postural gait disorders, sensory impairments, autonomic dysfunction, and mental and cognitive impairments.

The main thing is that the hands are shaky and uncontrollable. The main activities of people rely on their hands, and their hands tremble badly, which has a great impact on their lives. When it's so bad, I can't even eat, and of course I can't write or anything.

What are the symptoms of late Parkinson's loyalty? In the later stages of Parkinson's disease, you will have a shaking of your head, a shaking of your hands, and in severe cases, you will walk slowly.

There are many symptoms to choose from in the advanced stage of Parkinson's disease, so if you have a condition, you can go directly to solve it later.

Parkinson's patients will have many symptoms in the later stages, and if we find them in the future, we will solve these problems as soon as possible.

The late symptoms of Parkinson's disease are of great concern, and Parkinson's is a common neurological disease that will gradually worsen. Many people miss Parkinson's because they don't know the knowledge of Parkinson's disease, and when they find it, it is already at an advanced stage.

Late Parkinson's Symptoms:

1. Autonomic dysfunction.

Generally, hailstones in the later stage will cause a certain degree of neurological disorder, which directly affects the patient's various systems. Patients often have intractable constipation and rarely intestinal obstruction. Dyskinesia in the esophagus, stomach, and small intestine can cause dysphagia, esophageal spasms, and gastroesophageal reflux.

2. Emotional and intellectual changes.

Patients with Parkinson's disease may also present with psychiatric symptoms, which manifest as symptoms of depression and dementia. Some patients have indifferent expressions, depressed mood, slow response, poor self-control, lack of self-confidence, pessimism and misanthropy, suspiciousness, stubbornness, fear, irritation, etc., which is one of the late symptoms of Parkinson's.

3. Loss of smell.

This is a late symptom of Parkinson's disease, and many people with Parkinson's disease have a reduced or absent sense of smell. These defects appear early and do not appear to be related to the duration of the disease.

The late symptoms of Parkinson's disease have a great impact on patients, seriously reducing the quality of life of Parkinson's patients, resulting in their inability to live a normal life. Therefore, it is necessary to carry out Parkinson's disease as soon as possible** to control the disease. If you find it, please be sure to go to the hospital in time to receive it**, and don't let these unnecessary factors lead to long-term trouble.

Patients with Pachammed Hollowkinson syndrome. Clinically, the erection is now resting tremor. Machine gun movement is sluggish, and postural balance is impaired.

Occurs in patients with intermediate and advanced stages. It is difficult to stand up, it is easy to fall backwards, and sometimes the patient walks faster and faster with very small steps after stepping on the stool, and cannot stop in time.

Parkinson's disease, this disease is a chronic progressive disease, although some drugs can improve its progression, but so far, there is no drug that can completely ** Parkinson's disease, so Parkinson's disease, generally speaking, after 3 to 5 years, will gradually worsen, advanced Parkinson's disease, what are the clinical manifestations, then there are mainly the following aspects, the first is that there will be mental decline, many patients with Parkinson's disease, after the advanced stage, his memory, Including higher cortical function cognition, including finding the way home, there will be functional decline, so this higher cortical function is often called dementia caused by Parkinson's disease, or dementia caused by PD.

Then the second one will have emotional changes, many Parkinson's disease patients in the later stage, he will be apathetic, depressed, unresponsive, and then poor self-control, and some patients will lack self-confidence, pessimistic and misanthropy, and even some patients, sensitive and suspicious, full of suspicion, anxiety, fear, and easy to accumulate heat and other bad emotions, a small number of paroxysmal sexual impulses, aggressive behavior, in the later stage of Parkinson's disease, due to nutritional dysfunction, including his eating dysfunction, Wasting may occur.

In addition, patients with Parkinson's disease will also have a low sense of smell, and patients with Parkinson's disease are prone to salivation due to his swallowing dysfunction, that is, he keeps drooling, this drooling is not due to the increased saliva secretion, but due to the dysfunction of saliva swallowing, so his saliva is all flowing out of the mouth, so he constantly needs a towel to wipe it, and Parkinson's disease patients, in the late stage, he will have severe motor dysfunction, At this time, we need to strengthen nursing to prevent the occurrence of bedsores and lung infections, of course, Parkinson's disease will also have sleep dysfunction in the later stage, so because I can't sleep at night, the muscles of the whole body are stiff, so I will be sleepy during the day.

Late symptoms of Parkinson's disease, including motor symptoms, psychiatric symptoms, and autonomic symptoms, can become worse.

Motor symptoms are dyspraxia or inability to perform voluntary movements, difficulty initiating, decreased movement, decreased spontaneous automatic movements, and decreased amplitude of movement. Patients in the terminal stage can only be paralyzed in bed, because muscle function declines, and they are prone to falling pneumonia, bedsores, etc.

Depression and anxiety are aggravated in patients with psychiatric symptoms, and even patients have hallucinations after taking the drug, mainly visual hallucinations, and will see vivid phantoms that do not exist in life, and patients are also prone to hurt themselves and their families.

Autonomic dysfunction, such as significant sweating, dyspepsia, intractable constipation, restless sleep at night, and restless legs syndrome in some patients.

The advanced symptoms of Parkinson's disease include severe limb tremor, slow movements, drooling, pain, constipation, etc.

Parkinson's disease is a chronic disease with a long course of illness, so the symptoms that may occur in the later stages may vary.

Common symptomatic manifestations include:

Sluggishness in movement: Often, the body feels "slow" and it is difficult to start or change movements.

Difficulty speaking: often difficulty speaking or swallowing.

Ataxia: Unstable movements such as hand tremors and foot tremors are common.

Balance disorders: Balance is often unstable and prone to falling.

Fluctuating psychological status: Anxiety, depression, obsessive-compulsive, or cognitive impairment are common.

Other symptoms: Eye twitching, pharyngeal difficulty, muscle relaxation, urinary incontinence, etc. may also occur.

Symptoms of advanced Parkinson's disease can seriously affect the patient's daily life, so medical help should be sought promptly.

1. Mental retardation. At this time, the memory of patients with occlusion is obviously reduced, and there will be obstacles in thinking, loss of discernment, language impairment, and greatly reduced comprehension and judgment ability, and dementia day by day.

2. Mood changes. Some patients will be depressed, indifferent, depressed, very slow to respond, poor self-control, lack of self-confidence, pessimistic and misanthropic; There are also some patients who are sensitive and suspicious, full of suspicion, anxiety, fear, anger and other bad emotions.

3. Emaciation. Weight loss is rapid, mostly due to reduced food intake. The body will become very weak, so that the body.

The late stage of Parkinson's disease is more often characterized by symptoms such as increased muscle tone, resting fibrillation, autonomic disorders, decreased movement, and mental disorders

1. Increased muscle tone. Patients with advanced Parkinson's disease will have significantly increased muscle tone, which may be accompanied by joint pain due to obstruction of local blood circulation.

2. Resting fibrillation. In the late stage of Parkinson's disease, tongue, mouth sores, jaw, limbs, head tremors, etc., which are difficult to control through self-awareness.

3. Autonomic nervous system disorder. Patients with advanced Parkinson's disease will have symptoms such as excessive state sweating, intractable constipation, frequent urination, urgency, and incomplete urination.

4. Reduced exercise. In the late stage of Parkinson's disease, the automatic arm swing movement is significantly reduced, the lower limb activity gait is slowed, and it is like dragging bushes, and even dare not cross obstacles, and some patients will have a panicked gait.

5. Mental disorders. Psychiatric symptoms such as anxiety, depression, sleep disturbances, and dementia can occur in the late stages of Parkinson's disease.

The main symptoms of Parkinson's patients in the late stage are: further deterioration of the condition, obvious impairment of walking, and even complete loss of the ability to perform pure feasting; The patient loses the ability to care for himself and needs to be cared for by others; difficulty speaking and swallowing; The body makes noise and shows some "involuntary movements", that is, "dyskinesia"; The joints of the limbs are twisted and deformed.

This different person may behave differently.

In the very advanced stages of Parkinson's disease, symptoms often become more severe and complex. The following are some of the common symptoms of late-stage Parkinson's disease:

Severe tremor (tremor): Tremors may become more pronounced and difficult to control in the most advanced stages, affecting areas such as the hands, legs, jaw and face.

Motor dysfunction: Patients with advanced Parkinson's disease may experience severe motor impairments, including rigidity, bradykinesia, and postural instability. These symptoms can lead to an increased risk of difficulty walking, clumsiness, and loss of balance.

Autonomic dysfunction: Advanced Parkinson's disease may cause autonomic dysfunction with problems such as orthostatic hypotension, digestive problems such as constipation and gastric emptying, and urinary frequency and incontinence.

Cognitive and psychiatric changes: Some patients may experience cognitive decline, memory impairment, and mental symptoms such as depression, anxiety, hallucinations, or delusions in the later stages.

Sleep disturbances: People with advanced Parkinson's disease may experience sleep disorders such as insomnia, dreaminess, sleepwalking, nocturnal awakenings, and daytime sleepiness.

It is important to note that the symptoms and course of Parkinson's disease vary from person to person, and different patients may exhibit different symptoms and severity. Early measures such as medical management, medications, training, and supportive care can help reduce symptoms and improve quality of life. In the advanced stages of Parkinson's disease, patients and families should work closely with their doctors to develop appropriate care plans and support systems.