Are there any serious consequences of the occasional use of glucocorticoids?

Glucocorticoids have ***, occasional use of glucocorticoids will not have any effect on the body, if long-term use of high-dose glucocorticoids, then it will affect the body, there will be a variety of ***. It can adversely affect the metabolic function of the body, a large amount of glucocorticoids will cause hyperadrenal cortex, people will have buffalo back, centripetal obesity, and ** will also appear purple striae. High blood pressure, high blood sugar, and high blood lipids may occur.

Long-term use of glucocorticoids in large quantities can also cause damage to bones. This can lead to calcium loss, osteopenia, and osteoporosis. Long-term use of glucocorticoids can lead to weakened immune system, which can also reduce resistance and cause infection.

If there is already an underlying infection in the body, it can easily get worse. Long-term use of glucocorticoids should not be stopped abruptly, and if the drug is stopped suddenly, adrenal insufficiency will occur. <>

Long-term use of glucocorticoids also increases the risk of infection, especially atypical bacterial infections or more severe infections. It may also cause gastrointestinal tract, peptic ulcer and perforation, adverse reactions of the nervous system, and cause irritation and insomnia. Long-term use of glucocorticoids can also lead to cardiovascular complications, leading to sodium and water retention, and elevated blood lipids leading to hypertension and atherosclerosis.

Long-term use of glucocorticoids can also cause cataract glaucoma, which can lead to increased pressure in the eye, inducing glaucoma or cataracts. The use of glucocorticoids can also cause neuropsychiatric abnormalities, causing symptoms such as nervousness, insomnia, emotional changes, and in some cases, suicidal tendencies. Glucocorticoids can also induce seizures, so we must pay attention to it, do not use glucocorticoids for a long time, and if there is any discomfort in the body, go to a regular hospital in time.

Occasional use will not have serious consequences, and the harm to the body is not particularly great, so do not use it often.

Increasing the chance of infection can also lead to insomnia, it can also lead to poor development of the nervous system, it can lead to increased blood pressure, osteoporosis, obesity** with wrinkles.

It may cause uremia, nephritis, which will harm kidney function, and will also affect the body's metabolism, and may cause drug allergies.

Answer] :d adverse reactions caused by long-term and large use of glucocorticoids. Hypercortical syndrome.

Full moon face bridge bump, buffalo back, high blood pressure, hirsutism, diabetes, **sensitization, etc. It is caused by GCS and metabolic disorders. Induce or exacerbate the sensation of noisy reinfection.

The main reason is that hormones reduce the body's resistance to pathogenic microorganisms. Induces or worsens ulcer disease. Induces high blood pressure and arteriosclerosis.

Osteoporosis, muscle atrophy, and delayed wound healing. Induces psychosis and epilepsy. Inhibits children's growth and development.

a.The level of ACTH in the blood is elevated.

b.The amount of ACTH in the blood is decreased.

c.The amount of ACTH in the blood does not change.

d.The level of ACTH in the blood decreased first and then increased.

e.The amount of ACTH in the blood is sometimes high and sometimes low.

Correct answer: B

Glucocorticoids have a wide range of effects, and all its effects can be summarized as one advance and one retreat, two less and three more, four antibodies and five metabolisms in medicine. A common adverse reaction is that patients will have a full moon face and central obesity, and it will promote gastric acid secretion, which may lead to the occurrence of gastric ulcers.

When it comes to absolute contraindications, I summarize it into two points, the first point is that in the absence of drugs, anti-inflammatory with glucocorticoids will aggravate the infection. The second point is that the drug should never be stopped immediately, because long-term use of glucocorticoids will cause the human adrenal cortex to atrophy and reduce ACTH secretion. Otherwise, symptoms may worsen.

1. Cushing syndrome: It generally disappears on its own after stopping the drug.

2. Three highs: the drug disappears after stopping the drug, and the three highs should be used with caution.

3. Infection: Secretive observation of changes in the condition.

4. Ulcers: add drugs to neutralize gastric acid or inhibit gastric acid.

5. Nervous system: add diazepam, etc.

6. Osteoporosis: regular radioactive examination; At the same time, it is combined with calcium supplementation and vitamin **.

7. Affect wound healing: there is no rule of law.

8. Affect children's growth and development: there is no rule of law.

9. Endogenous GCS hyposcrution: slowly decrease when the drug is stopped, and cooperate with systemic symptomatic**.

10. Steroid myopathy: It cannot be completely recovered after stopping the drug, so the drug should be stopped immediately if symptoms appear.

11. Rebound phenomenon and drug withdrawal syndrome: or slowly stop the drug, with assistance**.

12. Glaucoma and cataract: Intraocular pressure is measured daily and ocular signs are closely observed.

Anyway, hormones are the best way to use them in no way, or auxiliary. Try not to use it. It really doesn't work, you can only use it, but you can also get the desired effect. After all, it is a medicine that is poisonous. When the medicinal properties are more toxic than the toxicity, it makes sense to use them!