What medicine is most effective for Parkinson s disease and what medicine is most effective for Park

First of all, we should be reminded that Parkinson's syndrome, Parkinson's disease, and Parkinson's superposition syndrome are three different diseases, so it is necessary to determine that it is Parkinson's disease. If the diagnosis is not correct, taking medicine is not the right symptom. In the case of Parkinson's disease, reasonable medical treatment will definitely help.

In Parkinson's disease and Parkinson's superposition syndrome, drugs do not work well.

Secondly, it is necessary to find out what period of the disease is in. Needless to say, the drug for Parkinson's disease must be medopa (or xining). However, for the initial stage of mild disease, adjunctive drugs may be used.

Examples include amine oxidase inhibitors, amantadine, anticholinergics, or dopamine agonists. The simple use of adjuvant drugs is effective for patients with early Parkinson's disease, but not for a long time, and core drugs must be added to have significant effects.

Again, pay attention to the dosage of the medication and the time of taking it. The dosage of the drug is taken as an example, at least 1 4 capsules at a time, 3 times a day, and the time to take the medicine should be one hour before meals, and eating after meals will affect the absorption of the drug. In particular, milk and high-protein foods affect drug absorption the most.

As the disease progresses, the dose of the drug should be gradually increased, for example, 1 4 capsules of medopa are usually ineffective for patients in the middle or advanced stages, and the dose needs to be increased appropriately.

Longyuan extinguishing decoction is used, and Parkinson's disease is classified by traditional Chinese medicine**

At present, most TCM practitioners treat the symptoms of movement disorders in Parkinson's disease as the main syndrome differentiation criteria, and the efficacy criteria also take the improvement of movement disorder symptoms as the main observation index, and generally make a comprehensive judgment based on the patient's neurological symptoms, signs and work ability. There are four criteria for the efficacy of Parkinson's disease.

After the clinical :*, the main symptoms and signs of the patient basically disappeared, and the patient was able to take care of himself and participate in part of the work.

Significant effect: The main symptoms and signs of the patient are significantly reduced, and the basic life or work ability is improved.

The main symptoms and signs have improved, and the exercise is still difficult or slower than the normal person.

Ineffective: **Those who have not improved in symptoms and signs after 3 months.

To prevent Parkinson's disease, it is necessary to recognize that it is a degenerative neurological disease, which can be understood as the process of aging, and it can also be understood as the process of accelerating the decline of the body by harmful toxins.

In most cases, there is no such thing as what medicine for Parkinson's is the most effective, and you need to follow your doctor's advice and use relevant drugs according to the specific situation**. Parkinson's patients need to go to the hospital for examination in time and apply relevant drugs to achieve the effect of controlling the disease and avoid excessive impact on the quality of life of patients. The drugs commonly used in **Parkinson's are benserazide, levodopa, carbidopa, levodopa, which have a good relieving effect on symptoms such as rigidity, oligotransferia, and tremor.

Drugs such as pramipexole and ropinirole can also be used, which can have a more ideal effect on early Parkinson's disease.

Parkinson's patients need to pay attention to their daily habits, adjust their dietary structure reasonably, balance nutrition, not be picky eaters, and eat high-quality protein foods appropriately, such as milk and eggs. Pay attention to rest, don't stay up late to ensure sleep time and sleep quality, don't overwork, keep your mood comfortable and happy, and don't have too many ups and downs.

In general, patients with Parkinson's can take medications or surgeries depending on their condition. When a person with Parkinson's disease is affected in their ability to perform daily life and work, appropriate medications** can reduce symptoms to varying degrees. Its drugs** are more effective than alternative drugs, such as compound levodopa and dopamine agonists, but often cannot completely prevent the progression of the disease.

Surgery may be considered for patients with a significant decrease in the efficacy of long-term medications** and dyskinesia at the same time. However, surgery only improves the symptoms, not **, and medication is still needed after surgery.

If the patient has Parkinson's disease, for these patients, what drugs need to be taken to work better must be determined in combination with the specific situation of the patient. For example, if the patient is showing tremor of the limbs, these patients can be treated with drugs such as medopa or levodopa, pramipexole, and tasida, which can have a good effect on patients with tremor.

If the patient has myotonia as the main symptom and there are no contraindications to these patients, they can take drugs such as Antan, Amantadine, etc. If the patient has simultaneous tremors of the limbs, bradykinesia, muscle rigidity, abnormalities in posture and gait. These patients are primarily treated with medopa, as well as dopamine agonists**.

Parkinson's disease continues to progressively worsen once it develops and should be started as soon as possible**. In general, a single drug** or a combination of drugs acting on different targets in small doses is used to control symptoms as much as possible and maintain the effectiveness of the drug for a longer time.

Medications: include disease-modifying medications and symptomatic medications. Disease modification** can delay the progression of the disease, and the main drugs with disease modification effects are type B monoamine oxidase inhibitors (MAO-B inhibitors, including selegiline + vitamin E and rasagiline), dopamine receptor agonists (DR agonists, such as pramipexole), and high-dose (1200 mg D) coenzyme Q10.

Principle of preferred drugs: For patients with early-onset type (without intellectual impairment), compound levodopa, non-ergot DR agonists, MAO-B inhibitors, amantadine, and entacapone bidopa tablets can be selected; In late-onset patients or those with reduced intelligence, compound levodopa is preferred, and DR agonists, MAO-B inhibitors, or catechol-O-methyltransferase (COMT) inhibitors can be added when the efficacy is reduced, and anticholinergics are not used as much as possible.

Medications: All medications for Parkinson's disease should be used under the guidance of a doctor, and the dosage should be increased or decreased according to the doctor's instructions, avoid sudden discontinuation or dosing, and follow the doctor's instructions for regular check-ups.

Anticholinergics: mainly indicated for patients with pronounced tremor and younger age (under 60 years of age), the main drug is trihexyphenidyl

Directions: 1-2 mg, 3 times a day.

Note: Patients with angle-closure glaucoma and patients with prostatic hypertrophy are contraindicated.

Main***: dry mouth, blurred vision, constipation, difficulty urinating, affecting cognition, and in severe cases, hallucinations and delusions.

Amantadine: It is mainly suitable for improving symptoms such as oligoactivity, rigidity, and tremor, and may be helpful for patients with dyskinesia.

Usage: 50-100mg, 2-3 times a day, the last of the day should be taken before 4 pm.

Note: Patients with renal insufficiency, epilepsy, severe gastric ulcer, and liver disease should use with caution; Do not use in lactating women.

Major***: restlessness, confusion, distal limb reticular greenfall, ankle edema, etc., are rare.

Compound levodopa: It is still the most basic and effective drug for this disease, with regular-release agents such as medopa and xining, controlled-release agents such as medopar hydrodynamic balance system and xining controlled-release agent, and diffuse medopa in water solvents. Methyl levodopa and ethyl ester have good curative effects on tremor, rigidity, bradykinesia, etc.; Aqueous solvents are suitable for patients with morning stiffness, postprandial "off" state, and dysphagia; Methyl levodopa and ethyl ester are indicated for patients with advanced stage and severe motor complications.

Usage: Initial dosage, 2-3 times a day, gradually adjust the dose until the efficacy is satisfactory and there are no side effects, it is advisable to take the drug 1 hour before or after meals.

Note: Use with caution in patients with active peptic ulcers; Contraindicated in patients with angle-closure glaucoma and psychosis.

Main***: including peripheral nerve symptoms and central nervous symptoms, the former is nausea, vomiting, hypotension, arrhythmia (occasionally), and the latter has symptom fluctuations, dyskinesia and psychiatric symptoms.

Parkinson's medications** are as follows:

1. Anticholinergics, symptomatic tremor and muscle rigidity, anticholinergics are effective, have poor efficacy on bradykinesia, are suitable for patients with prominent tremor and younger age, commonly used drugs are Antan, Kaimajun, etc.

2. Amantadine, amantadine can promote the release of dopamine from nerve endings and reduce the reuptake of dopamine, improve the symptoms of Parkinson's disease such as tremor, muscle rigidity and bradykinesia, suitable for patients with mild symptoms, can be used alone, but the effect is not maintained for several months.

3. Dopamine substitution, which can supplement the deficiency of dopamine in the striatum nigra, is the most important method for Parkinson's disease. Since dopamine cannot penetrate the blood-brain barrier, the use of substitute** to supplement its precursor levodopa, when levodopa enters the brain and is taken up by dopaminergic neurons, it is decarboxylated and converted into dopamine to play a role, and levodopa** can improve all clinical symptoms of patients with Parkinson's disease.

Parkinson's disease is an extrapyramidal degenerative necrotic disease in middle-aged and elderly people, with a course of about 15-20 years, and it becomes more and more severe with age. Parkinson's principle is a combination of multiple drugs, any drug is gradually increased from a small dose, many drugs for Parkinson's disease have ***, there is a process of adaptation when you start to eat, there are five main classes of drugs:

1. L-dopa, such as medopa.

2. Dopamine receptor agonists, such as Senforol, Tasuda, Ropironi, etc.

3. Monoamine oxidase B inhibitors, such as selegiline, rasagiline, etc.

4. Anticholinergic drugs, such as antamidine, amantadine, etc.

5. COMT inhibitors, in advanced patients with dyskinesia or switch phenomenon, this drug can increase the utilization of dopamine in the central nervous system.