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In clinical work, there are many drugs for Parkinson's disease. Since each drug has different advantages and sensitivities, among the drugs**, the appropriate drug should be selected according to the individual characteristics, the patient's sensitivity to the drug, and the severity of the disease.
Low-dose drugs are commonly used in early patients**. When resistance develops, it can be achieved by gradually increasing the dose or a combination of drugs**.
Parkinson's disease, also known as parkinsonism, has a relatively high incidence in the elderly, often manifested as resting tremor, muscle rigidity, etc. Commonly used drugs include compound levodopa, medopa, selegiline, pibedidil, etc. There are a few other medications that need to be taken together**.
For example, vitamin E, etc. are all acceptable, and dopa receptor drugs are usually preferred. Trihexyphenidyl is also available, which is mainly indicated for patients with significant tremor.
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1) If there are Parkinson's patients in the family, then pay attention to remind them of the correct and healthy diet, because a reasonable and healthy diet can also improve this condition, it is recommended that the patient eat more cereals, vegetables and fruits, pay attention to vitamin and protein supplements, and it is recommended to eat less fatty meat. You can buy 15 grams of longan meat and 15 grams of fried jujube kernels. Add longan meat and fried jujube kernels to water and fry them into juice, and then add an appropriate amount of white honey to serve.
Take 2 times daily, morning and evening. It has a tonic effect on people who have suffered from Parkinson's disease for a long time and qi and blood deficiency.
2) Exercise**: Encourage patients to put on and take off soft and loose clothes by themselves to strengthen upper limb activities and upper and lower limb coordination training. For those who have difficulty getting out of bed on their own, the head of the bed can be raised and a rope can be knotted at the end of the bed to facilitate the patient to pull and get up.
Avoid sitting on soft sofas and chairs with deep recesses, try to sit on seats with armrests on both sides, and raise the back of the chair to make it have a certain inclination to make it easy to stand up. If there are small broken steps, you can wear shoes with large friction on the soles, such as rubber soles, so that the walking is not easy to slip. Avoid wearing shoes with heels or oblique heels when rushing forward gait, as flat heels can slow down the forward gait.
A cane can help the patient limit the forward gait and maintain balance. Exercising every day until you sweat slightly is the best way to exercise, and Parkinson's patients should remember to exercise more.
3) Traditional Chinese medicine**: Traditional Chinese medicine recognizes Parkinson's disease as belonging to the category of traditional Chinese medicine tremor syndrome, and many Parkinson's patients use Longyuan Quan Tremor Soup, which has a better effect, and many patients can control their head or limb shaking and trembling. The main clinical manifestations are as follows:
In mild cases, the head shakes, wooden expressions or hands and feet tremble slightly, and the severed ones see the head shake, the limbs shake, and even the limbs are restrained and lose the ability to take care of themselves, and the disease is also called shaking tremor. The effect of traditional Chinese medicine Parkinson's disease in the early stage is remarkable, and it is recognized by the majority of Parkinson's patients because of its small size. Once the diagnosis is confirmed, drugs should be administered as early as possible, and medications should be given early in the course of the disease, which will help the symptoms of Parkinson's disease progress, so that the patient can achieve a better quality of life.
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Medication is the preferred modality for Parkinson's disease and is a very effective means throughout the process. Drugs** mainly include: levodopa, dopamine agonists, monoamine oxidase (MAO)-B inhibitors, anticholinergics, amantadine, catecholamine-O-methyltransferase (COMT) inhibitors.
Levodopa (eg, carbidopa-levodopa, dopaserazide) or dopamine agonists (eg, pramipexole, ropinirole) may be used as initial ** drugs in patients with Parkinson's disease. MAO-B inhibitors (including selegiline and rasagiline) may mildly improve symptoms of Parkinson's disease and are mainly used in patients with early Parkinson's disease and may not improve significantly in patients with advanced Parkinson's disease. Anticholinergic drugs (trihexyphenidyl) are reserved for younger patients with prominent tremor symptoms and are not recommended for older patients or those with dementia or without tremor.
Amantadine is a relatively weak-acting anti-Parkinson's disease drug, which has low toxicity and is most useful for patients with early or mild Parkinson's disease.
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In the early stage of Parkinson's disease, it mainly relied on drugs, and there was no best drug, only the most suitable plan for the condition, such as the common drugs in Parkinson's disease, including medopa, Tasuda, Cilin, amantadine, and first-line clinical drugs such as entacapone and pramipexole. According to the different stages of development of the patient and the severity of the disease, the professional doctor of neurology will make a more appropriate combination to achieve the best effect and reduce the quality of the drug.
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**Medications for Parkinson's disease include combined levodopa preparations, dopamine agonists, monoamine oxidase inhibitors, anticholinergic agents, and amantadine. Commonly used drugs are trihexyphenidyl hydrochloride, amantadine, selegiline, pramipexole hydrochloride, entacapone, etc.
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Hello, Parkinson's is a degenerative disease of the central nervous system predominantly substantia nigra. Common symptoms include resting tremor, rigidity, bradykinesia and decreased movement, flexion posture, postural dysreflexia, and freezing.
Opinions: It is recommended to use extracerebral dopamine decarboxylase inhibitors: medopa, or dopaminergic feignant agonists: bromocriptine, combined with drugs for antidepressant and anxiety symptoms.
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Parkinson's disease is a neurodegenerative disease common in middle-aged and elderly people, generally manifested as tremor, static tremor, drooling, choking, muscle stiffness, slow movement and other symptoms of traditional Chinese medicine ** Parkinson's advantage is to adjust the twelve meridians of the human body, the active ingredients of the drug directly intervene in the brain nerve cells, promote cerebral circulation, repair damaged neuronal cells, stimulate the potential of the human body, and quickly restore physiological functions. It can gradually and completely get rid of the long-term dependence on western drugs such as medopa, alkylamine, and antan.
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Due to individual differences, there is no absolute best, fastest and most effective medication, except for commonly used over-the-counter drugs, the most appropriate drug should be selected under the guidance of a doctor in full combination with individual circumstances.
The goal of the drug is to effectively improve symptoms, improve the quality of life and work ability, and strive to achieve "low-dose drug maintenance that can achieve more satisfactory clinical effects", and strive to reduce the drug and related complications.
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You should go to a regular hospital for diagnosis, and the doctor will prescribe the drug for the disease.
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The correct way of traditional Chinese medicine is to warm up and replenish Zhongjiao!
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The choice of drug varies greatly from person to person, and the choice needs to be based on the patient's age and the patient's main symptoms. For example, the patient's clinical symptoms are already relatively severe, mainly manifested by increased muscle tone, and drugs such as levodopa need to be taken. If the patient is predominantly resting tremor, drugs such as trihexyphenidyl may be taken.
If the patient develops dyskinesia, amantadine may be used if necessary.
Suggestions: It is recommended that patients with Parkinson's disease should pay attention to emotional adjustment, eliminate the fear of disease, and participate in outdoor sports on a regular basis, especially in balance function training. Be sure to get enough sleep and have regular outpatient follow-up.
Parkinson's disease is an extrapyramidal degenerative necrotic disease in middle-aged and elderly people, with a course of about 15-20 years, and it becomes more and more severe with age. Parkinson's principle is a combination of multiple drugs, any drug is gradually increased from a small dose, many drugs for Parkinson's disease have ***, there is a process of adaptation when you start to eat, there are five main classes of drugs:
1. L-dopa, such as medopa.
2. Dopamine receptor agonists, such as Senforol, Tasuda, Ropironi, etc.
3. Monoamine oxidase B inhibitors, such as selegiline, rasagiline, etc.
4. Anticholinergic drugs, such as antamidine, amantadine, etc.
5. COMT inhibitors, in advanced patients with dyskinesia or switch phenomenon, this drug can increase the utilization of dopamine in the central nervous system.
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1.Levodopa: the most basic drug, which can increase the level of dopamine in the brain, but because of the poor efficacy, it is necessary to take adjuvants at the same time, such as benzylserazine hydrochloride, entacapone, carbidopa, etc., to increase the efficacy and reduce adverse reactions;
2.Pamine receptor agonists: such as piribedil, pramipexole hydrochloride, bromocriptine, etc.;
3.Neuroprotective agents: such as selegiline hydrochloride, rasagiline, etc. There are also medications for complications such as mental disorders and cognitive impairments.
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1. Anticholinergics, symptomatic tremor and muscle rigidity, anticholinergics are effective, have poor efficacy on bradykinesia, are suitable for patients with prominent tremor and younger age, commonly used drugs are Antan, Kaimajun, etc.
2. Amantadine, amantadine can promote the release of dopamine from nerve endings and reduce the reuptake of dopamine, improve the symptoms of Parkinson's disease such as tremor, muscle rigidity and bradykinesia, suitable for patients with mild symptoms, can be used alone, but the effect is not maintained for several months.
3. Dopamine substitution, which can supplement the deficiency of dopamine in the striatum nigra, is the most important method for Parkinson's disease. Since dopamine cannot penetrate the blood-brain barrier, the use of substitute** to supplement its precursor levodopa, when levodopa enters the brain and is taken up by dopaminergic neurons, it is decarboxylated and converted into dopamine to play a role, and levodopa** can improve all clinical symptoms of patients with Parkinson's disease.
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What is the best medicine to take for Parkinson's Parkinson's disease is a common neurodegenerative disease, and at this stage, Parkinson's disease is mainly with the help of drugs and surgery. However, when Western medicine is used in a certain link, there will inevitably be a "switch phenomenon" of drug reactions, and the adverse reactions of Western drugs are very large, and patients are more worried; Surgery** is also risky and not a one-time solution, so many patients are reluctant to undergo surgery. Parkinson's disease belongs to the "tremor" of Chinese medicine, and Chinese medicine does have a great effect on this disease.
Regardless of patients in the early stage of Parkinson's disease or patients after preoperative surgery, they can intervene in traditional Chinese medicine to get better**.
Parkinson's traditional Chinese medicine believes that it is because of the deficiency of the spleen, liver and kidney, and generally uses the classic Chinese medicine prescription "Longyuan Tang", but this first Parkinson's disease prescription is not used immediately, and the doctor must complete the addition, subtraction and compatibility of medicinal materials according to the specific condition of the patient. Lu Lao stressed that it is dangerous to search for prescriptions from the Internet to grab medicine and take it, and be careful to aggravate the condition or cause other serious problems. According to statistics, Parkinson's patients have chosen the combination of traditional Chinese and Western medicine**, and they also independently choose traditional Chinese medicine** and take traditional Chinese medicine for a long time.
A Parkinson's patient's hands trembled very much, and for taking Western medicine, the patient said, "I changed several Western medicines, and I felt *** big, so I kept searching for prescriptions on the Internet to grab the medicine and take it." Traditional Chinese medicine does have an effect on Parkinson's disease, but it is important to distinguish between the syndromes and treat them. ”
Because traditional Chinese medicine has thoroughly analyzed Parkinson's disease more than 2,000 years ago, it belongs to "tremor" in traditional Chinese medicine. The most common syndrome type of this type of disease is liver and kidney insufficiency, followed by qi and blood insufficiency, and the third type is excessive phlegm and turbidity. Patients are often mixed with several syndrome types, so they must be treated differentiated, and prescriptions must be used under the guidance of a Chinese medicine practitioner. ”
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Parkinson's disease is a degenerative degenerative disease of old age. Its main clinical manifestations are muscle rigidity, resting tremor, bradykinesia, and postural gait abnormalities.
There are many types of Parkinson's disease medications, and the only ones that are effective in improving symptoms are dopamine-based drugs, such as medopa. The initial dosage of this medicine starts with 1 4 tablets taken orally 3 times a day, and its maximum dosage is 250 mg 3 times a day. If the dose is increased again, there is no obvious effect on the improvement of symptoms, and there will be undesirable ***.
In Parkinson's disease**, medication is generally not recommended if there is no significant cognitive impairment under the age of 60. You should continue to be involved in work and daily life, and do some self-training, including some aerobic exercise, slow walking, cycling, etc.
People over the age of 60 who have cognitive impairment or who have special needs for work can take medication. Tremor is evident with trihexyphenidyl and amantadine taken orally, but it is not recommended for the elderly with prostatic hyperplasia and older people. Dopamine agonists, such as piribedil, can be used alone or in combination with medopa.
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