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ALS, also known as motor neuron disease, is a chronic condition. The clinical characteristics of this disease are: 1. Insidious onset and progressive aggravation, mainly manifested as distal limb muscle atrophy, weakness, hypertonia, fasciculation, difficulty in moving, bulbar paralysis, dysarthria, choking on eating, breathing and swallowing disorders, hyperreflexia and positive pathological features.
There is usually no sensory impairment. 2. The disease is most affected by middle-aged people, mostly between 40-50 years old, but it can also occur in childhood and after the age of 70. There are 2-3 times more males than females, and some patients have a positive family history, usually inherited in an autosomal dominant manner.
The earliest symptoms of motor neuron disease are: 1. Asymmetric weakness of the limbs, or unclear arthria, the onset of the upper limbs mostly starts from shoulder weakness, and sometimes after a slight local injury, distal weakness is often more obvious, manifested as holding weakness, about 35% of patients are first in the upper limbs, and about 40% of patients start from the lumbar segment of the spinal cord, these patients limp due to unilateral foot drop or difficulty standing due to weakness.
2. Early muscle cramps are common, and they are mostly in the proximal and distal muscles of the lower limbs affected. Muscle beats can be a cause for concern, and sometimes muscles beat months before weakness and muscle atrophy. 3. With the development of the course of the disease, almost all patients with the onset of limbs will have bulbar symptoms, and the weakness will be further aggravated, and the muscle beating will become insignificant.
Conversely, people who develop bulbar symptoms end up with extremity symptoms.
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ALS, also known as motor neuron disease, has early symptoms of muscle atrophy and muscle weakness. The most common type of ALS is amyotrophic lateral sclerosis, amyotrophic lateral sclerosis generally occurs after 40, the early symptoms are inflexible finger movements and weak strength, and then the hand muscles will begin to atrophy, and gradually develop the muscles of the forearm, upper arm and shoulder girdle, and then there will be spastic paralysis of the lower limbs, increased muscle tone and other symptoms, the course of the disease will continue to develop, and the patient will eventually die due to ventilator paralysis or complicated respiratory infection. Other types show symptoms such as muscle weakness, muscle atrophy, and choking on drinking water in the early stages.
If you feel unwell, be positive**, even if the condition is not optimistic, be optimistic and don't worry too much.
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ALS is a neuronal disease, and muscle weakness is a muscle disease, and the two are different.
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People with ALS tend not to live long, usually less than 10 years.
ALS people will gradually start from the limbs, slowly accumulate the muscles of the whole body and cannot move, and finally affect the patient's breathing muscles, swallowing muscles, speech muscles, etc., and the whole body cannot move. In this case, it is easy to die from complications, and the life expectancy is generally within 10 years after the disease.
ALS**:
The condition of amyotrophic lateral sclerosis is still unknown. In 20% of cases, it may be related to heredity or genetic defects. In addition, some environmental factors, such as heavy metal poisoning, can cause motor neuron damage. The main theories of the causes of motor neuron damage are:
1.Neurotoxic substances accumulate and glutamate accumulates between nerve cells, causing damage to nerve cells over time.
2.Free radicals damage nerve cell membranes.
3.Nerve growth factor deficiency prevents nerve cells from growing and developing sustainably.
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ALS is medically known as motor neuron disease, which is caused by motor nerve damage, including upper motor neuron damage and lower motor neuron damage, which is manifested as muscle weakness, atrophy and quadriplegia throughout the body. Physical examination may reveal muscle weakness, muscle atrophy, and fasciculations, as well as tendon hyperreflexia and positive pathological reflexes. Because the pathogenesis is not yet clear, there is no particularly good way.
Nutritional support is mainly given**, and if the patient has difficulty swallowing and chewing, nasogastric feeding or gastrostomy surgery can be performed. If the respiratory muscles are paralyzed, a tracheostomy should be done as soon as possible to maintain breathing with a ventilator. At present, there is an internationally recognized drug called Lirutai, which can be used for ALS, which has a certain delaying effect on the progression of ALS.
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In about 10 years, you can observe the specific situation, and if it is serious, you should go to the hospital in time.
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It's pretty much the same, but the cause is not the same as the speech** the way is different.
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This may be potassium deficiency, you can do a neurology department to do an electrolyte look, or take a blood test to see if the hyperthyroidism is normal
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1. ALS is a common name for a group of motor neuron diseases, because the patient's motor nerve cells are invaded, the patient's muscles will gradually atrophy and weakness, and even paralysis, and the body will seem to be gradually frozen. Because the sensory nerves are not damaged, the disorder does not affect the person's intelligence, memory, or sensation.
2. ALS is still unknown, and there are very few people who may be related to heredity and genetic defects. In addition, some environmental factors, such as genetics and heavy metal poisoning, may cause motor neuron damage. There is also the possibility of the accumulation of neurotoxic substances, glutamate accumulation between nerve cells, which can cause damage to nerve cells over time.
3. The symptoms of muscle atrophy in the early stage are not very obvious, and the muscle strength and muscle tone do not change much, and the muscle atrophy of the upper limbs appears. There will be sensory disturbance or loss of pain sensation in one or both muscles of the limb. It will also be accompanied by dizziness, tinnitus or menstrual irregularities, and if the tongue coating is red, it is also a symptom of muscle atrophy.
Precautions: Through the above introduction, I think everyone knows some of the symptoms of ALS and muscle atrophy, in fact, these two diseases have some similarities in some aspects, but most of the symptoms are still different, so we need to observe carefully and don't make our own conclusions.
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