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1 Receptor blockers such as prazosin, bunazosin, and doxazosin (Biaxin) have no significant effect on blood uric acid when lowering blood pressure**. The selective 1-blocker nafperidil has been reported to elevate serum uric acid.
Long-term use of receptor blockers propranolol (propranolol), atenolol (aminopropoll), metoprolol (betaloclix), penbrolol (cyclopentodol), or celinolol (Deleon) can cause elevated serum uric acid.
There are many types of calcium channel blockers, and their antihypertensive effects and effects on blood uric acid are also different. Calcium channel blockers that can cause elevated serum uric acid for long-term use include nisoldipine (nifedidine), sinidipine, banidipine, nifedipine (heartache), nicardipine (nifebenzamine), and diltiazine (fendra). Nitrandipine (nifethaneylpyridine) has little effect on serum uric acid.
Amlodipine (Luohuoxi) and levamlodipine (Shihuida) have little effect on serum uric acid and can be used in patients with hypertension. Due to individual differences in antihypertensive drugs, care should be taken to monitor serum uric acid levels during application.
ACE inhibitorsAt present, there is a consensus on the effect of such antihypertensive drugs on serum uric acid. Some scholars believe that angiotensin-converting enzyme inhibitors, such as benazepril and lisinopril (Diyilo), can dilate renal blood vessels, increase renal blood flow, promote uric acid excretion, and reduce blood uric acid levels. It has also been found that many hypertensive patients have elevated serum uric acid levels after taking such drugs (eg, benazepril) and returned to normal after switching antihypertensive drugs.
Therefore, if hypertensive patients need to use such antihypertensive drugs, they should closely observe the blood uric acid level, find abnormalities, and stop changing the drugs in time.
Angiotensin receptor blockers: These antihypertensive drugs have good antihypertensive effects. Losartan, telmisartan, candesartan cil, and olmesartan ciloxil have occasionally been reported to cause gout. Irbesartan and hydrochlorothiazide can also increase serum uric acid levels.
The nonpeptide-selective angiotensin receptor blocker eprosartan does not affect serum uric acid levels.
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Some patients only know how to "pay the bill" after going to the outpatient clinic to prescribe the medicine, and only remember to ask the doctor how to take the antihypertensive medicine after getting it at the pharmacy or the medicine window.
I went home and read the instructions and found that the dense small words on it were really difficult to read, and I finally saw the instructions for taking it, and after reading it, I found that there was a line written at the end of the sentence "Follow the doctor's instructions".
Have you ever had this experience? Today, Dr. Ha will talk to you about how to take blood pressure medication.
Take medicine first when you wake up in the morning
Our blood pressure also has a "biological clock", and when we get up in the morning, our blood pressure also "gets up".
Therefore, in order to "cater" to the peak of blood pressure, doctors often advise patients to:
For long-acting antihypertensive drugs taken once a day, it is recommended that you wake up in the morning, put a glass of water in hand (you can use a thermos cup at the head of the bed), take the antihypertensive medicine, and rest for a while before getting up to exercise.
There are also some patients who want to ask, so the doctor told me to take it 2 or 3 times a day, and when should I take the other meals?
After the morning peak, blood pressure rises again in the evening (around 17-18 o'clock) and then drops to a low point during the night. And most of the blood pressure drugs we take start to take effect 30 minutes after taking the drugThe effect is strongest after two or three hours after taking the drug, so it is recommended:
If you take antihypertensive drugs 2 or 3 times a day, the time of taking the "last two meals" has little to do with dietTake on an empty stomach or after a mealBoth.
Diuretics are also taken in the morning
Diuretics include:Furosemide tablets, hydrochlorothiazide tablets, spironolactone tabletsMany elderly patients with high blood pressure and heart failure take these drugs.
The main effect of this type of drug is to increase urination, so Dr. Ha Da recommends everyone:
To cure angina, also eat in the morning
Such drugs include:Isosorbide dinitrate tablets, isosorbide mononitrate tabletsWait. Depending on the dosage of the drug, there are those who take it once a day or those who take it three times a day.
The first meal of this class of drugs is also appropriateTake in the morning, because heart diseases such as angina, myocardial infarction, and acute myocardial ischemia are mostly in the early morning and morning.
Also, these drugs do not interact significantly with blood pressure medications and can be taken together.
Take the medicine with warm water
Many elderly patients are worried that their medication will cause hypoglycemia or low blood pressure, so they often choose to take the medicine with milk, which is actually wrong.
Milk itself is a high-protein food, on the one hand, it may form a protective film on the surface of the gastric mucosa to affect the absorption of drugs, on the other hand, the milk itself contains tyramine and other ingredients will also affect the absorption of drugs, so it is not recommended to use milk to take medicineWarm boiled water is the best choice
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