-
Motor neuron disease is a group of **unspecified choices** chronic progressive neurodegenerative diseases of bone marrow anterior horn cells, brainstem motor neurons, cortical pyramidal cells, and vertebral tracts.
MND is a progressive disease of the nervous system, the condition will gradually worsen, the patient may be paralyzed in three to five years, when the patient has difficulty swallowing and breathing, nasogastric nutrition and ventilator methods can be used.
Motor neuron disease (MND) is a clinical symptom caused by progressive apoptosis of motor neuron cells in the human nervous system. The main manifestations are muscle beating, atrophy, and pyramidal tract signs, which mostly occur in middle-aged and elderly men.
It is divided into four main categories, amyotrophic lateral sclerosis, progressive muscular dystrophy, progressive bulbar palsy, and primary lateral sclerosis. Patients with motor neuron disease may become paralyzed in 3 to 5 years, and when the respiratory muscles are involved, it may become difficult to breathe, and further progression of the disease can be life-threatening.
-
Choking on swallowing may occur after 2 to 3 years, which may cause difficulty breathing.
-
In the later stages of motor neuron disease, symptoms such as dyspnea may occur, and some patients develop the disease in the medulla oblongata. As a result, breathing and swallowing can be affected, making it difficult to breathe and requiring a ventilator to sustain life.
-
Motor neurons are neurons that are responsible for transmitting messages from the spinal cord and brain to the muscles and endocrine glands, innervating the activity of paraorganic fluids. Motor neuron disease (MND) is a rare disease that is a series of chronic progressive neurodegenerative diseases characterized by motor neuron changes. At present, the cause of the disease is not clear, and patients present with muscle weakness, muscle atrophy, bulbar paralysis, etc., and usually have no paresthesias.
The disease mostly occurs in middle-aged and elderly people, and the course of the disease is mostly 2 to 6 years, and most of them have a poor prognosis, and often die of respiratory muscle paralysis or lung infection due to respiratory muscle involvement.
There is still a lack of drugs that can effectively reverse or control the progression of the disease. The motor neuron disease pathogen is diverse and affects each other, so it must be a combination of multiple methods. The development of motor neuron disease (MND) includes a variety of non-pharmacological elements, symptomatic, and non-pharmacological factors.
At present, there is no specific diet to avoid for MND, and a balanced diet is sufficient.
The nursing of patients with motor neuron disease should always pay attention to the nutritional status, swallowing function and respiratory status of the patients, care about the psychological status of the patients, keep the environment clean and tidy, and reduce the occurrence of complications.
Take the drug according to the doctor's instructions, understand the possible adverse reactions of the drug, and regularly review the blood routine and liver and kidney function during the medication.
Depending on their condition, patients should do some appropriate exercises under the guidance of a doctor.
For patients who have been bedridden for a long time, the surrounding environment should be kept clean and tidy, and family members or nursing staff should help patients turn over, pat their backs, massage, and scrub on time every day to reduce the occurrence of complications such as infections and bedsores.
Patients with dysphagia should slow down their eating and try to avoid aspiration.
-
Spontaneous breathing can be caused by a variety of factors, but the most common is caused by damage to the respiratory center. For example, brain injury caused by cerebral vascular obstruction, stenosis or rupture, severe compression of brain tissue by intracranial hypertension or intracranial mass lesions, intracranial inflammation such as encephalitis and meningitis. There are also some patients who are unable to breathe spontaneously due to the loss of voluntary movement function of respiratory muscles, such as motor neuron disease, myasthenia gravis, etc.
Lesions of the respiratory system itself can also cause the occurrence of spontaneous breathing, such as open pneumothorax, severe pneumonia, etc.
-
Because the disease mainly affects the motor nervous system, there is usually no paresthesia or urinary or urinary disturbances during the course of the disease. Statistics show that limb weakness is more common in the onset site, and a small number of patients have dysphagia and dysarthria. Different disease subtypes have different sites of onset, disease duration, and disease progression.
MND is mostly sporadic, with onset between the ages of 30 and 60 years, more in men than in women, and usually has an insidious onset and progresses slowly. Knowing the early symptoms of MND can help detect the condition in a timely manner.
Motor neuron disease is a degenerative neurological disease that is specific, meaning that the first symptoms can manifest in a variety of ways depending on the patient. Most patients start with asymmetrical local limb weakness, such as stiffness in walking, procrastination, easy falling, and inflexible finger movements (such as holding chopsticks, opening doors, and fastening). Bulbar symptoms such as dysphagia and dysarthria.
A small number of patients present with respiratory symptoms. As the disease progresses, muscle atrophy, "flesh beating" sensation (i.e., fasciculations), cramps, and expansion to other muscles in the body gradually appear, and in the later stage of the disease, in addition to eye movements, all locomotor systems of the whole body are involved, involving respiratory muscles, dyspnea, respiratory failure, etc. Most people eventually die of respiratory failure or other complications.
-
Motor neuron disease (MND) is a serious neurological disease that occurs in people, causing great distress to the patient's life, and even leading to death. Therefore, we must actively discover the emergence of motor neuron disease in our lives and accept the disease, so as to be able to protect our young lives. So, how does MND kill?
There are many causes of death in people with MND, and here are the 7 major harms of this disease:
1. Classical amyotrophic lateral sclerosis, which mainly occurs in adults, can cause damage to the upper and lower motor neurons of patients, and is the spinal cord segment of Harbin patients;
2. Primary lateral sclerosis, a common upper motor neuron disease, is better than the classic amyotrophic lateral sclerosis, and the prognosis is also better;
3. Progressive spinal palsy will cause problems in the patient's subcranial motor neurons, resulting in dysphonia and dysphagia, often leading to aspiration pneumonia and death;
4. Progressive spinal muscle atrophy is a relatively variable motor neuron disease, which has a relatively high probability of death;
5. Flail arm and flail leg syndrome, patients will have muscle weakness and muscle atrophy, which will cause patients to be unable to take care of themselves;
6. It leads to asymmetrical local limb weakness, the patient walks inflexibly and is easy to fall, and it will affect the respiratory system, resulting in respiratory failure;
7. Frontotemporal dementia, which leads to the decline of executive function and is accompanied by cognitive impairment, which has a great impact on the patient.
-
Not necessarily. Problems with any part of breathing can lead to the inability to breathe spontaneously, including abnormalities in the central drive of breathing, nerve conduction abnormalities, respiratory muscle dysfunction, and abnormal thoracic movements.
For example, traumatic brain injury, cerebral hemorrhage, inflammation, tumors and other damage to the respiratory center, neuromuscular diseases, such as myasthenia gravis, respiratory muscle dysfunction, and open pneumothorax and other thoracic diseases, can lead to impairment of respiratory function, so that it is impossible to breathe on its own.
In addition, some autonomic factors may also cause patients to feel dyspnea and unable to breathe on their own, which requires a comprehensive judgment based on the condition.
-
MND can manifest as weakness and atrophy of the limbs, clumsiness and weakness of finger movements, muscle weakness and atrophy over the course of the disease, extending to the trunk and neck, and finally involving the facial and throat muscles. Patients may have bulbar paralysis, mostly in the late stage, the tongue muscles are first involved, manifested as tongue muscle atrophy, fasciculation, and tongue protrusion weakness, followed by pharyngeal, laryngeal, and masticatory muscle atrophy and weakness, resulting in the patient's slurred arthria, dysphagia, chewing weakness, and the orbicularis oculi muscle in the facial muscle is more obviously involved. There is often a pattern of disease progression in MND, usually from the upper extremity that is first affected, then to the contralateral upper extremity, to the ipsilateral lower extremity, to the contralateral lower extremity, and finally to the bulb involvement.
Motor neuron disease can be life-threatening, mostly within 3 to 5 years, death from respiratory muscle paralysis or lung infection, so motor neuron disease is more harmful. You can come to Beijing Renxuan Traditional Chinese Medicine to find Sheng Jinqiangfu**, and through one-to-one conditioning of Yiyuan Muscle Formula, the patient's symptoms can be improved.
-
This is related to lung use, lung capacity is small, it is recommended to exercise moderately every day to enhance physical fitness and enhance lung capacity.
-
Hello, MND is a group of chronic progressive degenerative diseases that mainly damage the anterior horn of the spinal cord, the motor nucleus and pyramidal tract of the cranial nerve. Paralysis caused by upper and/or lower motor neuron damage is the main clinical manifestation, and the combination of upper and lower motor neuron damage is the most common. As long as the patient suffers from this disease, the muscles first atrophy, and finally the patient dies due to the inability to breathe while the patient is conscious.
Therefore, this kind of patient is also called "ALS".
Suggestions: At present, this disease is a worldwide problem, and there is no effective method. The dyspnea you mentioned is caused by respiratory muscle atrophy and paralysis, and the problem of swallowing and choking can be solved by giving a lower gastric tube to avoid lung infection caused by repeated coughing.
The early stage of motor neuron disease is characterized by gradual muscle atrophy and weakness in one part of the patient's body, and many diseases have similar clinical manifestations in the early stage, and the age of onset of this disease is between 40 and 60 years old, which is also the stage of high incidence of cervical spondylosis. Many patients with cervical spondylosis can also have unilateral limb muscle atrophy and weakness in the early stage, so many patients mistakenly believe that it is cervical spondylosis, delaying the diagnosis. There is no difficulty in an advanced ALS person, and the diagnosis can be made by simply taking clinical data, but the difficulty in the examination of motor neuron disease is when it is atypical in the early stage, and it may be difficult to determine that it is an area of disease if there is no experience. >>>More
Since the nature of MND is unclear, there is no specific approach. >>>More
There will also be misdiagnosis of motor neuron disease, this situation needs to be examined in detail, generally the main feeling is unreliable, must be selected EMG evoked potentials, nerve conduction velocity is necessary, and the examination is carried out at the same time choose to go to a regular hospital for testing.
Hope it helps. There is currently no reliable method for motor neuron disease, it is a refractory disease, and the survival rate after the disease is generally found to be about 5 years, but there are many types of motor neuron disease, and the survival rate is not the same, with an average of about 5 years. However, in recent years, there have been gradual reports in clinical practice: >>>More
Motor neuron injury refers to damage to the anterior horn of the spinal cord, selective pontine motor nucleus, and chronic disease of the pyramidal tract. Occurs in the upper and lower parts of motor neurons at the poles, the nature of motor neuron degeneration. The bridge between nerve cells and cranial nerves, the telescopic anterior horn motor nucleus is significantly reduced, degenerated, the spinal cord in the neck, the heaviest injuries are lumbar distended, the medullary hypoglossal nerve nucleus and the suspected nucleus are also easily grasped, the motor cortex which is a huge pyramidal cell Bez cells may also have similar changes, but generally mild. >>>More