What do you know about the diagnosis of the initial symptoms of lateral sclerosis?

Amyotrophic lateral sclerosis is a disease that mainly refers to the patient's upper and lower motor neurons combined with the damage caused by mixed paralysis, once this disease occurs, it will seriously affect the quality of life of the patient, if the patient can not be carried out in time after the disease, if it is serious, it will directly endanger the patient's life, so it is very necessary to understand the initial symptoms of the disease, only in this way can it be detected and ** in time. So what are the initial symptoms of amyotrophic lateral sclerosis?

Amyotrophic lateral sclerosis is a disease that is very slow at the time of onset, but once the onset progresses quickly, patients will generally have symptoms of arm weakness and calf weakness in the early stage of the disease, and then with the gradual aggravation of the disease, the patient will slowly develop muscle atrophy, interosseous muscles, vermiform muscles and their thenar muscles are initially involved, and this kind of disease will slowly spread to adjacent and proximal muscle groups, and the condition of leg and upper arm involvement generally occurs at the same time. Once this kind of symptom occurs, the patient needs to pay attention, and should be diagnosed and treated as soon as possible, so that the patient will have a good effect after treatment.

In addition, amyotrophic lateral sclerosis will continue to cause the patient's tongue muscles, orbicularis oculi muscle and masticatory muscles to be involved after the occurrence of such diseases, when those positions are involved, the patient will of course have difficulty in swallowing and phonetic transcription pronunciation, and the symptoms of fasciculations will continue to slowly occur in the patient's limbs, body, corners of the mouth and its face, etc., such symptoms generally do not occur on time. When the patient's upper arm tendon reflex weakens or subsides, the patient's leg reflex surface will also produce more hyperactivity and tendon spasm. However, patients are generally unlikely to have symptoms of erectile dysfunction and sensory impairment.

In general, I firmly believe that you will have a certain understanding of the early symptoms of amyotrophic lateral sclerosis, after this understanding, once you see the suspicious symptoms in daily situations, you need to go to the hospital as soon as possible to carry out diagnosis and treatment, because the disease will be aggravated and even seriously endanger the personal safety of patients, so patients can only see and treat as soon as possible, so as to ensure the physical and mental health of patients.

ALS is also known as amyotrophic lateral sclerosis. Some early symptoms are progressive atrophy and weakness of the limb muscles, which usually start from the distal end of the limbs, and can also manifest as difficulty speaking, swallowing, dyspnea, easy fatigue, and often no sensory impairment.

Physical examination may show that distal muscle atrophy is more common in the upper limbs, with thenar and interosseous muscles of the upper and lower regions, often accompanied by fasciculations. At the same time, there is atrophy of upper and lower limb muscles and tongue muscles. Patients may also present with symptoms of mixed upper and lower motor neuron damage.

In the early stage, patients may only feel some symptoms such as slight fatigue and weakness in the body, sudden muscle jumps and easy exertion, if there is no timely intervention**, it may gradually develop into generalized muscle atrophy, or there will be dysphagia, and eventually evolve into respiratory failure and death.

Patients generally have symptoms of arm weakness and calf weakness in the early stage of the disease, and then as the disease gradually worsens, the patient will gradually develop muscle atrophy and interosseous muscles.

The condition of amyotrophic lateral sclerosis is still unknown. In 20% of cases, it may be related to heredity or genetic defects. In addition, some environmental factors, such as genetics and heavy metal poisoning, may cause motor neuron damage.

The main theories of the causes of motor neuron damage are:

1.Neurotoxic substances accumulate and glutamate accumulates between nerve cells, causing damage to nerve cells over time.

2.Free radicals damage nerve cell membranes.

3.Nerve growth factor deficiency prevents nerve cells from growing and developing sustainably.

2. Clinical manifestations.

Early symptoms are mild and can be easily confused with other diseases. Patients may only feel some symptoms such as weakness, flesh jumping, and fatigue easily, and gradually progress to generalized muscle atrophy and difficulty swallowing. Respiratory failure develops.

According to the clinical symptoms, it can be roughly divided into two types:

1.Limb-onset type.

Symptoms begin with progressive atrophy and weakness of the muscles in the limbs, and finally respiratory failure.

2.Bulbar onset.

When the limbs were still moving, they had difficulty swallowing and speaking, and soon progressed to respiratory failure.

Patients generally have symptoms of arm weakness and calf weakness in the early stage of the disease, and then with the gradual aggravation of the disease, the patient will gradually appear muscle atrophy, interosseous muscles, vermiform muscles and thenar muscles are involved in the early stage, and the disease will gradually spread to the adjacent and proximal muscle groups, and the lower limbs and upper limbs are generally involved at the same time.

The body may experience weakness in the limbs, dizziness, loss of appetite, stunted growth, and lack of sleep. So when we have this situation, we must go to the hospital for a physical examination.

Damage to the nerves of the brain, respiratory paralysis, mood abnormalities, sudden tantrums, vision loss, muscle atrophy, these are all effects.

In general, this disease is more common in the elderly, and there are many genetic factors, usually the upper limbs are damaged, spasms and weakness and other symptoms, and then slowly spread to the lower limbs, resulting in the deterioration of the condition, this disease is also caused by defects in the nerve center, so in this disease. During the course of the disease, the patient's mood changes greatly, especially when the emotional level is high, and there may be strong crying and laughing.

Amyotrophic lateral sclerosis is a rare disease and a chronic disease. This is due to an invasion or mutation of the patient's nervous system, which causes the patient's muscles to atrophy. The main manifestation of lateral sclerosis is muscle weakness in the patient's bones, and in severe cases, atrophy may occur, and the age of onset is usually between 30 and 60 years old.

However, there are more males than females. A little bit of non-atrophic lateral sclerosis can only help patients with remission, but it can't**. What is non-atrophic lateral sclerosis, which may be caused by genetic factors.

Of course, it can also be due to other factors that lead to amyotrophic lateral sclerosis.

Genetic factorsFor people with non-atrophic lateral sclerosis, the cause of the problem may be genetic. According to medical studies, some cases suggest that non-atrophic lateral sclerosis is hereditary, but in most cases no definitive ** has been found. In most cases, genetic factors are primarily related to reactions.

The next generation of people with non-amyotrophic lateral sclerosis and their offspring may have non-amyotrophic lateral sclerosis, which is a very important factor. Therefore, prenatal care should be done before childbirth so that prenatal diagnosis can better prevent the occurrence of diseases.

Motor neuron disease symptoms, duration, and degree of onset are related to the degree of right ventricular duct obstruction and whether the ductus arteriosus is closed. It is common to have a large number of capillaries on the surface, such as the lips, nail beds, bulbar conjunctiva, etc. Due to the decrease in oxygen in the blood and the lack of function, shortness of breath and cyanosis worsen if there are activities such as crying, mood, fatigue, coldness, etc.

Squatting is common in children. When they walk and play, they tend to actively cringe for a moment. During contraction, it reduces blood return, reduces cardiac load, increases internal circulatory resistance, reduces right-to-left shunt, and temporarily relieves hypoxia symptoms.

Children can't walk, and they usually like adults holding them up and bending their legs.

Introduction: Many people do not know what lateral sclerosis is, it is a chronic, progressive neurodegenerative disease, which is difficult to develop after an attack, and when the disease becomes more severe, it will cause the patient to have dyspnea or dysphagia, which may be life-threatening, and will be accompanied by different pains. This disease can not be **, and there will be many adverse reactions after the disease, such as skeletal muscle weakness, atrophy, etc., the general age of onset is between 30 and 60 years old, and there are more men.

Next, let's analyze with you, what are the effects of the symptoms of lateral sclerosis?

Lateral sclerosis, also commonly known as ALS, is a chronic, progressive degenerative disease that affects upper and lower motor neurons, as well as innervated trunks, limbs, etc. It is a type of motor neuron disease that is usually sporadic and familial. When patients have lateral sclerosis, they are generally weak and stiff in the lower limbs, which is more difficult in the process of walking, and slowly affects both upper limbs.

When patients have symptoms of lateral sclerosis, they are more likely to be agitated, and memory loss, including cognitive and intellectual decline, will cause dementia in the advanced stage, and language impairment, which may lead to inability to speak, vision loss, and facial paralysis. Patients may also often feel pins and needles or numbness, which is common in the back, lower legs, and upper limbs. In the early stage, people will become more and more clumsy, easy to fall, and at the same time begin to become wooden, and some patients will have symptoms of frequent urination, urgency, and urinary incontinence in the later stage.

Therefore, the impact on people's normal life is very large.

In the early stage of diagnosis, it is necessary not only to do a neurological examination, but also to cooperate with imaging examination and electromyography examination, a series of tests of serum special antibodies, nerve conduction velocity, and muscle biopsy in special cases.

Patients with lateral sclerosis present primarily with muscle weakness, amyotrophy, and pyramidal tract signs, and generally do not present with sensory and urinary and stool disturbances. Most patients begin in one upper extremity, but some may also begin in the lower extremity, and fasciculations may occur at the onset of the disease. Generally speaking, most of the distal muscle weakness is more obvious than the proximal end, when the disease begins to occur in the upper limbs, most of them first manifest as inflexible finger movements and weakened strength, and may be accompanied by ipsilateral difficulty in wrist extension, and some patients can also begin to have proximal weakness of the entire upper limb, followed by atrophy of small muscles of the hand such as thenar and vermiform, and can gradually develop into the forearm, upper arm and shoulder girdle muscle.

Extensor weakness is usually more pronounced than flexors, and patients may gradually develop spastic paralysis of the lower extremities, scissor gait, tendon hyperreflexia, and bulbar paralysis in advanced patients. Patients may present with dysarthria, slurred speech, and may have difficulty swallowing and chewing.

The body may experience weakness in the limbs, dizziness, hot-headedness, loss of appetite, and lack of sleep. So when we have this situation, we must go to the hospital to do the corresponding **.

It affects people's muscles, affects people's lives, affects their own walking, makes the body have no strength, and makes it impossible for them to do things.

In the early stages of primary lateral cord malacia, there are impaired mobility, limb incoordination, stiffness and weakness, and difficulty walking. If nerve damage is significant, the patient may have spasms and stiffness in the upper limbs and limbs, and examination may suggest signs of upper neuronal injury, such as increased limb muscle tone, tendon hyperreflexia, and positive pathological signs.

1. The first one is that there will be movement disorders, and patients with amyotrophic lateral sclerosis will have spastic paralysis and cerebellar ataxia. In the early stages of amyotrophic lateral sclerosis, patients may experience clumsiness and tremors in their hands, stumble and fall in their legs, and sometimes stutter when speaking.

2. Then there will be cranial nerve dysfunction, the patient will have vision loss caused by optic neuritis, as well as the dark spot in the center of the visual field, and the patient's pupil irregularity or narrowing plus nystagmus is also a common phenomenon. However, there will also be a small number of patients with trigeminal neuralgia.

3. There will be sensory impairment, which is often caused by spinal cord lesions, often with pinprick and numbness, banding and burning, or abnormal pain. Pain often occurs in the back, lower legs, and arms, and patients may also have pseudobulbar palsy, with varying degrees of speech and even vocal cord paralysis.