What causes high uric acid?

Introduction: Uric acid is too high because the body produces too much uric acid, and eating high-purine foods will cause the body to take in too much uric acid, coupled with the body's metabolism problems, unable to excrete uric acid, it will cause high uric acid. Because uric acid is excreted through the kidneys, if there is a problem with kidney function, it will lead to high uric acid.

There are also some people who usually like to drink, drinking too much alcohol will not only numb the nerves, but also make uric acid high, which is also because ethanol enters the body and needs the liver to assist in metabolism, when the liver metabolizes alcohol into formic acid, it will cause the metabolism and excretion of blood uric acid.

When the uric acid in the human body is too high, the blood flow will become very slow, which will cause the problem of fat metabolism, so that the basic metabolic function of the body is abnormal, so when the calorie intake into the human body is easy to cause obesity. In addition, if the uric acid is too high, joint pain will also occur, which is also because uric acid will form crystals in the joints, and the accumulation in the blood and joints will cause joint enlargement, and develop into joint inflammation, which will cause joint pain. In addition, it can also lead to kidney disease, when uric acid is too high, it will accumulate in the kidneys and cause kidney problems, such as kidney stones, kidney failure and other problems.

We must drink more water every day, because drinking more water can help the discharge of uric acid, and can also discharge some unnecessary uric acid from the body, and usually exercise more in the process of exercise can promote the body's blood circulation, help the discharge of uric acid, and can also strengthen the basic metabolic function of the human body, reduce the fat accumulation in the human body, and make the human body healthier.

Finally, you must pay attention to your uric acid in your daily life, if the uric acid exceeds the normal range, it is possible to develop gout, so you should do it as soon as possible**.

It may be due to eating too much greasy food, or because of an irregular diet, or because of excessive stress, or because of unhealthy lifestyle habits.

If uric acid is high, it is because the body's metabolism is reduced, so it will lead to high uric acid.

It is related to the body's metabolism and diet, and sometimes there is a problem with the body's endocrine, which may lead to such a result.

The body's uric acid is mainly caused by excessive production or too little excretion, and hyperuricemia. Generally, uric acid is produced too much, including several reasons, such as familial hyperuricemia, that is, people with a history of gout are prone to excessive purine base production of uric acid due to defects in enzyme metabolism. In addition, in certain disease states, such as tumors, leukemia, myeloproliferative diseases, polycythemia, etc., especially malignant tumors, will cause cell metabolism to be significantly accelerated, which will increase the production of purine base into uric acid, so too much uric acid will be produced.

Hyperuricemia can also occur due to decreased uric acid excretion due to certain kidney diseases. Diseases such as glomerulonephritis and tubular damage can lead to decreased uric acid excretion, which can lead to an increase in uric acid.

Finally, there is the effect of the drug. Because many chemotherapy drugs, aspirin, diuretics, etc., can cause uric acid excretion disorders or excessive uric acid production, thus causing hyperuricemia.

1.Excessive intake of exogenous purines.

If you often like to eat high-purine foods such as animal offal or seafood, or have the habit of smoking and drinking, it is easy to cause excessive purine intake, which will lead to high uric acid.

2.Excessive production of endogenous purines.

If there is a problem with internal diseases, such as acute and chronic leukemia, polycythemia, multiple myeloma, hemolytic anemia, lymphoma and a variety of solid tumors, chemotherapy will cause excessive uric acid production due to the large breakdown of intracellular nucleic acids.

3.Impaired uric acid excretion.

If there is a kidney disease, it is easy to cause the excretion of uric acid to be blocked, and the accumulation of uric acid in the body will occur, because uric acid is mainly excreted through the kidneys.

There are three causes of high uric acid.

1.Some special diseases.

One of the important causes of high uric acid is disease, especially kidney-related diseases. Problems with kidney function can cause uric acid to rise. The main reason is that one of the main functions of the kidneys is to remove waste products from the body's metabolic activities.

If the kidney function is impaired, then uric acid cannot be excreted from the body in time, so uric acid in the blood will rise. In addition to kidney disease, diseases such as obesity, diabetes, blood disorders, tumors, etc., can also cause elevated uric acid.

2.Genetic factors.

Purines are present in the nucleus of cells, and from a microscopic perspective, purines in the nucleus are the main components of genetic material. One of the conditions that cause high uric acid is myeloproliferative disorder due to the increase in red blood cells. However, such cases are not too common.

3.Purines that are seriously exceeded.

If we overeat foods that contain a lot of purines, such as fish, legumes, seafood and alcohol. This directly increases the synthesis of uric acid in the body, eventually causing high uric acid.

The cause of high uric acid is caused by abnormal purine metabolism in the body, high uric acid can cause pain in the patient's joints, uric acid can crystallize in the human body and form stones, and in the most severe cases, gout will occur.

It is recommended to use some drugs that specifically control the content of uric acid at the time of **, and at the same time, it is necessary to control the diet not to eat too much food with high purine content (such as: animal offal, seafood, thick broth, etc.).

You can usually eat more alkaline fruits and vegetables, and you can also drink some alkaline water, which is of great help to dilute uric acid, and you should exercise more to improve your immunity.

1. Eating too much high-purine foods in the diet will cause high uric acid.

If it is caused by dietary factors, it is necessary to control the diet reasonably and avoid eating foods high in purines.

2. It can also cause elevated uric acid when suffering from diseases, such as arteriosclerosis, hyperlipidemia, coronary heart disease or diabetes.

3. Drug factors are one of the reasons for inducing high uric acid, and relevant matters should be paid attention to when taking a certain drug for a long time. When long-term medication induces high uric acid, some measures should be taken in time to adjust it.

The reasons for high uric acid are as follows: 1. Excessive intake of high-purine diet, foods with high purine content include animal offal, pork belly, sausages, shiitake mushrooms, seafood, deep-sea fish roe, spinach, broth, hot pot, etc. 2. Nephropathy and renal insufficiency affect the patient's uric acid metabolism, so that the uric acid in the blood cannot be excreted from the body in time, and the accumulation increases.

3. Due to the patient's own genes, such as special constitution, certain enzymes may be lacking in uric acid metabolism. 4. Poor habits such as lack of exercise and drinking less water lead to centripetal obesity and slow metabolism in the body.

Uric acid is deposited in various parts of the body and in various joints, causing pain in various parts of the body, and long-term recurrence.

In the end, it not only makes people feel unbearable pain, but also affects the health of the joints, and the joint deformities appear, making people unable to take care of themselves. **For gout, we must grasp the key point, that is, to discharge urate from the body and prevent the deposition of uric acid crystals. When uric acid is too high, the use of succumbing herbal tea can play a role in lowering uric acid, which can promote metabolism in the body and help uric acid to be excreted from the body quickly.

Quit "three waters" and drink "three teas":

1 water, puree.

There are some people in life who prefer to drink soup, and they can eat soup from time to time, generally broth, pork rib soup, seafood soup, etc.

These soups contain a lot of purines, and if you eat too much, the uric acid content in the body will definitely rise.

2 water, sweet drink.

People who don't like to drink water, but like to drink drinks with flavor, have only a lot more in life.

Although I know that plain water is the healthiest for the body, there are always people who want to replace it with drinks, thinking that the same is to replenish water, and the effect is the same.

In fact, people who often drink sweetened drinks are more likely to form a large amount of uric acid in the body, which cannot be excreted from the body normally, resulting in serious harm.

3 water, drink.

Everyone has drunk some alcohol to some extent, such as white wine, beer, red wine, etc.

However, people who often drink a lot of alcohol will have a great impact on the body, because a large intake of alcohol will lead to an increase in the level of uric acid in the blood, and the more serious consequence is to induce a gout attack.

Common causes of hyperuricemia include the following:

genetic factors, due to mutations in various purine-metabolizing enzymes;

Food factors, the common is excessive intake of high-purine foods, foods with high purine content, including animal offal, seafood, beer, foods with high fructose content, alcohol, etc.;

Drug-induced hyperuricemia, common drugs include diuretics, cyclosporine or tacrolimus, low-dose aspirin;

Diseases and states associated with hyperuricemia, including renal failure, metabolic syndrome, diabetes mellitus, untreated hypertension, after strenuous exercise.

Dr. Han Xue, Attending Physician, Department of Nephrology.

Beijing Friendship Hospital affiliated to Capital Medical University is a third-class hospital.

High uric acid is due to eating too many foods and purines.

There are many reasons for high uric acid, common irregular diet, long-term heavy drinking, eating meat, broth, seafood, high-sugar drinks, etc., will form hyperuricemia, and most of the hyperuricemia has no symptoms, only found during the physical examination, high uric acid may be silent in the joints, causing gout, can cause kidney and brain lesions. It is recommended to have regular medical examinations and detect them in time**. Lai Yan headlines.

1.The diet is not suitable.

Eating too much animal food, especially pork liver, kidney, cerebral marrow, sardines and other foods, is very rich in purines, which can easily lead to excessive uric acid production, resulting in an increase in uric acid.

2.Impaired uric acid excretion.

In patients with kidney disease, the excretion of acidic metabolites is dysfunctional, which can easily lead to elevated uric acid. Frequent consumption of carbonated drinks and large amounts of alcohol leads to an increase in acidic metabolites in the body, which affects the excretion of uric acid and increases uric acid.

3.Drugs***.

It mainly includes the influence of thiazide diuretics and some anti-tuberculosis drugs, which cause an increase in uric acid levels.

4.Influence of genetic factors.

Due to the influence of genetic constitution, the dysfunction of metabolic purines is caused, and uric acid is elevated in the case of normal purine intake.

The causes of high uric acid in the human body include improper diet, excessive uric acid production, uric acid excretion disorders, renal insufficiency, etc.

1.Caused by unreasonable dietary habits, such as patients eating too much food with high purine content, such as seafood, animal offal, boiled broth, beer, etc., are easy to cause an increase in uric acid in the body.

2.Excessive uric acid production in the body, generally more common in gout patients, is mostly hereditary, mainly related to the activity and concentration of various enzymes in the patient's body, resulting in excessive uric acid production in the patient's body.

3.Uric acid excretion disorder, decreased renal tubular secretion and increased reabsorption, resulting in uric acid can not be excreted out, resulting in increased uric acid.

4.Patients with renal insufficiency have an increase in uric acid due to the accumulation of uric acid in the body due to abnormal metabolic function of the kidneys in the body.

Eating habits need to be adjusted.

1. Non-disease elements.

1. Diet: Long-term intake of purine-rich foods, such as animal offal, seafood, thick broth and beer, can lead to an increase in uric acid production in the body, resulting in high uric acid. This group of people can be improved by adjusting their diet.

2. Drugs: taking furosemide, hydrochlorothiazide and other drugs can cause metabolic disorders, reduce the excretion of uric acid, and thus cause high uric acid; Taking propranolol and other drugs can lead to a decrease in renal blood flow and glomerular filtration rate, and reduce the excretion of uric acid, resulting in high uric acid. Such people can consult a doctor and stop or change the drug under the guidance of the doctor.

3. Exercise: When exercising excessively, if there is no timely replenishment of water or less water supplementation, it can lead to hemoconcentration, thereby causing high uric acid. These people can improve by adjusting their exercise patterns, exercise intensity, or by properly hydrating.

Second, the disease ** element.

1. Hyperuricemia: Under the normal purine diet, due to the excessive production of uric acid in the body and/or the decrease in uric acid excretion, the blood uric acid concentration measured by the patient on the same day exceeded 420 mol l, but the onset of ** wind indicates that he has primary hyperuricemia.

2. Gout: Gout is a joint disease caused by the deposition of monosodium urate in the body, which is directly related to hyperuricemia caused by purine metabolism disorders and/or uric acid excretion disorders. The clinical characteristics of gout are high blood uric acid, fever, fatigue, joint swelling and pain, and in severe cases, joint destruction or kidney damage.

3. Hematologic diseases: patients receiving chemotherapy for lymphoma or patients with acute and chronic leukemia, polycythemia, multiple myeloma, hemolytic anemia and other diseases will have a large amount of purine nucleic acid in their bodies, resulting in excessive uric acid production and high uric acid. In addition, patients may also have concomitant manifestations of primary disease, such as anemia and lymphadenopathy.

4. Kidney disease: renal insufficiency, chronic kidney disease and other diseases can lead to a decrease in uric acid excretion, resulting in high uric acid. In addition, patients may also have symptoms such as urine changes and eyelid edema.

5. Congenital purine metabolism disorder: due to congenital defects, there is a problem with the feedback mechanism in the body, and the metabolic level of purine-related substances cannot be regulated normally, resulting in high uric acid. In addition, patients may have symptoms such as joint pain, convulsions, and ataxia.

6. Others: glycogen storage disease, diabetic ketoacidosis, hypothyroidism and other bradyclide diseases can also cause high uric acid.

In summary, there are many reasons for high uric acid, if the uric acid level is still high after adjusting the diet, stopping or changing the drug, and changing the exercise intensity, the patient should go to the endocrinology department or rheumatology and immunology department of the hospital in time for treatment, and identify it as soon as possible through uric acid measurement, ultrasound examination, X-ray examination, etc., and carry out targeted treatment**.