What is coagulation and what is coagulation disorder?

Normal people have normal coagulation function, and abnormal coagulation function will develop in two directions, and some abnormalities are easy to form thrombosis, and blood vessels are blocked to produce hypercoagulability; There is also a common situation where the coagulation function is insufficient and causes bleeding, so whether it is a thrombosis or bleeding, it is necessary to check the coagulation function. Because platelets are related to bleeding and coagulation, in addition, if the number of platelets is normal and the function is suspected to be abnormal, then you can further check the platelet function test, which is called the platelet aggregation function test; In addition, the coagulation function is mainly checked, and the coagulation function reflects whether the function of coagulation factors in the blood is normal except for platelets. Because coagulation is a very complex process, in addition to platelet involvement, there are 12 coagulation factors to be involved, if there is a lack of a certain will cause bleeding, common hemophilia, is the first coagulation factor deficiency, the patient will have abnormally serious bleeding, so if you encounter abnormal thrombosis and abnormal bleeding, go to the Department of Hematology of Internal Medicine, check the number of platelets, platelet function and coagulation factors, determine what is the cause, and determine the diagnosis after targeted correction.

Coagulopathy refers to bleeding disorders caused by deficiency or abnormal function of coagulation factors.

Coagulation disorders are divided into two categories, hereditary and acquired, with the well-known condition of the hereditary type called hemophilia. For hemophilia, a lifelong disease, it is more important to stop the progression of complications in a sustained, long-term manner than to simply stop bleeding**.

Gao Xinqiang, deputy director of the Medical Safety and Blood Division of the Medical Administration of the National Health and Family Planning Commission, pointed out that hemophilia is a "major disease" among rare diseases, which is very harmful, and the diagnosis rate in China is low, and repeated bleeding and refractory complications lead to a high disability rate of patients, and often accompany patients for life.

Currently, substitution is the main method of preventing and a**bleeding in patients with hemophilia, i.e., infusion of exogenous coagulation factor preparations. Long-term standardized supplementation of coagulation factors can avoid or slow the development of physical disability in patients.

Coagulation dysfunction refers to a series of bleeding symptoms in the human body due to a decrease in the concentration or activity of coagulation factors in the body. Coagulation dysfunction is a large group of diseases, including a variety of diseases, the most common are hemophilia A, hemophilia B, von Willebrand disease, vitamin K deficiency, rat poisoning, warfarin poisoning and disseminated intravascular coagulation, etc., the most prominent clinical manifestations of these coagulation dysfunction diseases are bleeding symptoms, which can be manifested as ecchymosis of the mucous membrane, nasal and gingival bleeding, blood in the urine, hematemesis, melena and so on. Regardless of the coagulation dysfunction, the body's coagulation time will be affected and prolonged, and it is often necessary to replenish plasma, replenish cryoprecipitate, and apply drugs such as vitamin K**.

Therefore, coagulation dysfunction diseases include a variety of diseases, which need to be given differently for different **.

Thrombocytopenia leads to poor coagulation and requires an increase in platelets.

The number of platelets and the concentration are low, to put it bluntly, the blood is too thin, and a cut can't stop the bleeding. If you have any questions, please feel free to ask.

Coagulation diaorders are bleeding disorders caused by deficiency or dysfunction of coagulation factors. A typical example is hemophilia, which is characterized by bleeding from soft tissues, muscles, and weight-bearing joints. Bleeding tendencies are usually present in early childhood, and mild can be diagnosed in adolescents and even adults.

The earlier the bleeding symptoms appear, the more severe the disease. Patients may present with minor trauma or severe bleeding after surgery, often with bleeding that does not stop during tooth extractions or minor surgeries.

1. Coagulation refers to the process in which the inactive coagulation factors in the blood are activated in an orderly and amplified manner and transformed into coagulation factors with protein degradation activity, that is, the process of a series of enzymatic reactions of the so-called "coagulation waterfall theory". The final product of coagulation is the conversion of fibrinogen to fibrin in plasma.

2. There are 14 coagulation factors directly involved in the coagulation process, and the coagulation process is divided into exogenous coagulation and endogenous coagulation according to the different initiation links. These two pathways are common pathways after the activation of coagulation factor 10 until fibrin formation, and coagulation disorders are mainly seen in hemophilia, fibrinogen deficiency, etc.

1. Blood coagulation is blood coagulation, which means that the blood of the human body has the function of changing from a liquid state to a solid state, and blood coagulation is also an important physiological function of the human body to stop bleeding. If there is a problem with blood clotting, the patient will have obvious bleeding symptoms, such as hemophilia patients are due to blood clotting disorders, patients are not easy to stop bleeding after trauma since childhood, subcutaneous or intramune, joint bleeding and so on.

2. Hemagglutination is achieved through the amplification reaction of a series of coagulation factors. There are two kinds of coagulation pathways in the human body: exogenous coagulation pathway and endogenous coagulation pathway, no matter which coagulation pathway is disordered, it will lead to blood coagulation dysfunction, and the patient will manifest as subcutaneous ecchymosis, nasal cavity, gum bleeding, or it is not easy to stop bleeding after traumatic surgery. In general, routine coagulation tests can be done to find out which clotting route is the problem.

Generally, APTT is an index that reflects the endogenous coagulation pathway, and PT is an indicator that reflects the exogenous coagulation pathway.

Question 1: What are the causes of poor coagulation function, and is it serious? Analysis:

Hello, poor coagulation function may be related to the bottom of platelets, and it will also be related to coagulation factors, if thrombocytopenia or less coagulation factors or congenital deficiency, it will cause coagulation dysfunction, if the poor blood drinking function will cause bleeding to stop bleeding slowly, serious will continue to flow Suggestions: It is recommended to check the cause in detail in the hospital, these diseases in the hematology department can generally be detected, I wish you an early ** Disease analysis: Hello, acquired coagulation dysfunction is more common, Patients often have multiple clotting factor deficiencies; Vitamin K plays an important role in the coagulation process, and deficiency can cause vitamin K-dependent coagulation factors

It is recommended to go to a professional large-scale hematology department for a comprehensive examination, and actively cooperate with the attending physician to treat the symptoms after diagnosis**. I wish you good health.

Question 2: What should I do if my blood clotting function is not good If it is because of long-term vegetarians, it is recommended to eat more eggs.

Be healthy on your own! See a doctor if you are sick.

It is necessary to maintain proper exercise, balanced eating habits and good cultivation.

The occurrence of disease is cumulative over the days and months; Early detection, early **, smart move.

It is recommended to treat it with heat-clearing and antidote + qi-activating blood stasis medicine, qi-invigorating blood stasis and blood stasis dissipation.

Avoid frying greasy and cold foods. You can drink more Pu-erh tea or cassia tea, and drink Pu-erh tea with honey.