What is drug induced hypertension? What is drug induced hypertension? Be detailed

The clinical manifestations of drug-induced hypertension are hypertension after medication, or further increase in blood pressure or rebound or even hypertensive crisis in hypertensive patients**. Generally, the disease is mild and can be reversed after discontinuation of the drug, and occasionally serious complications such as hypertensive encephalopathy, cerebrovascular accident and renal insufficiency occur.

Advice 1: Drink water even if you are not thirsty Hypertension is one of the common diseases in internal medicine. **People with unknown hypertension are called primary hypertension or secondary hypertension.

In summer, the weather is hot, the metabolism is vigorous, and the amount of sweating is more, after the human body loses a lot of water, the blood volume of the whole body will decrease significantly, on the contrary, the viscosity of the blood will increase, which may lead to thrombosis, increasing the risk of myocardial infarction and stroke. Many people with high blood pressure do not realize this, do not pay attention to replenishing more water, and think that there is no need to drink water in a hurry if they are not thirsty, which is actually a big misunderstanding. Thirst is a strong response of the human nervous system to the lack of water in the body, and if you feel thirsty, your body is already in a more serious state of "dehydration".

Therefore, patients with high blood pressure should replenish water in time in summer, whether they are thirsty or not, in order to help reduce blood viscosity, in addition, drinking more water can also promote metabolism. Make it a habit to drink a glass every morning after waking up and a glass of water before going to bed at night. The "water" above refers to plain water, not sugary or carbonated beverages.

Patients with high blood pressure should not drink more sugary drinks in summer, and can appropriately drink cool and antipyretic drinks such as chrysanthemum tea and wolfberry tea. Advice 2: No matter how hot it is, you have to move When the weather is hot, you sweat when you move, which makes many people with high blood pressure, especially the elderly, shy away from exercising.

In fact, exercise can improve the elasticity of blood vessel walls, effectively improve the spasm of small blood vessels, and allow large and small blood vessels to maintain good contraction and diastolic function. It is not an exaggeration to say that exercise is "the blood vessels". People with high blood pressure should move in the summer, no matter how hot it is.

The key is to control the intensity and duration of exercise. For middle-aged and elderly people, slower-paced, low-intensity whole-body exercise is the mainstay. For example, tai chi, magnolia boxing, going up and down stairs, cycling slowly, etc., some community-attached fitness equipment is also a good choice, such as waist twisters, stretchers, and so on.

Traveling is also a type of exercise, but it is best not to travel to the plateau area for patients with high blood pressure who have heart disease, and before going out, people with high blood pressure should check whether they are carrying enough antihypertensive drugs. Advice 3: The temperature of the air conditioner should not be too low Many patients with high blood pressure usually control their blood pressure well, but in summer, their blood pressure is unstable, which is related to the improper use of air conditioning.

Some people like to turn the air conditioner on very low, especially when they come home from outside, hoping that doing so will cool themselves down as soon as possible. In this way, when it is hot and cold, the blood vessels will suddenly change from the original diastolic state to a constricted state, which lays the groundwork for the increase in blood pressure. After staying in an air-conditioned room for a long time, there is a heat wave as soon as you go out, and your blood vessels will dilate, so that your blood pressure will fluctuate constantly.

If the patient reduces the amount of medication at this time, it will be difficult to control the disease.

The following types of drugs are commonly used to cause an increase in blood pressure.

1) Non-steroidal anti-inflammatory drugs, such as aspirin, indomethacin (indomethacin), ibuprofen, analgin, diclofenac, piroxicam and acetaminophen.

2) Female oral contraceptives are mostly composed of progestogens and androgens, such as norethindrone, noorgestrel and their compound preparations.

3) Adrenocorticosteroids include glucocorticoids, mineralocorticoids, anabolic hormones, glucocorticoids such as hydrocortisone, cortisone, prednisone, prednisolone, dexamethasone, betamethasone, etc.; mineralocorticoids such as dehydrocorticosterone; Anabolic hormones such as testosterone propionate, progesterone, nandrolone phenylpropionate, etc.

4) Epinephrine drugs, such as epinephrine, norepinephrine, isoproterenol, hydroxylamine, ephedrine, phenylketone amine, naphthazoline (nasal drops), hydroxyzoline, etc.

5) monoamine oxidase inhibitors, which can increase blood pressure when used in conjunction with tyramine-rich foods (such as cheese, bananas, and lentils); If used in combination with epinephrine drugs, it can even induce hypertensive crisis.

It refers to the use of drugs, resulting in the patient's blood pressure rising, and beyond the normal range, or hypertension patients, in the process of using drugs, blood pressure further increases, or the blood pressure that has fallen to normal rebound, and some even appear hypertensive crisis, drug-induced hypertension, it is a kind of secondary hypertension, due to the pharmacological effect of the drug itself, caused by the interaction of poison and drugs, so drug-induced hypertension is foreseeable in most cases, The appearance of hypertension can also be prevented by adopting certain measures.

In the case of secondary hypertension, there is a category of factors that are caused by drugs, but rarely the term drug-induced hypertension.

These drugs mainly include: glucocorticoids (such as prednisone), contraceptives, sympathomimetics such as ephedrine, and licorice in traditional Chinese medicine.

Birth control pills Long-term use of this pill can cause or worsen high blood pressure, usually after a few months of taking the drug.

Transient increases in blood pressure after the use of certain drugs are called drug-induced hypertension and should fall under the category of secondary hypertension;

1. Calcium channel blockers: amlodipine, lasidipine, felodipine;

2. ACE II: also known as angiotensin-converting enzyme inhibitors, such as captopril, benazepril, enalapril;

3. Angiotensin receptor antagonists: candesartan, valsartan, olmesartan, telmisartan;

4. Receptor blockers: represented by metoprolol;

5. Diuretics.