Precautions for glimepiride, dosage of glimepiride

The initial dose is 1 mg once a day, preferably with breakfast, and is increased by 1, 2, 3, 4, and 6 mg every 1 to 2 weeks according to the results of blood glucose monitoring, with a maximum dose of 8 mg for individual patients.

Dosage should generally be based on blood glucose levels, and the smallest dose should be used to achieve satisfactory glycemic control. The initial dose and maintenance dose are determined based on the results of regular blood glucose and urine glucose monitoring, and monitoring blood glucose and urine glucose can also help determine whether the drug has primary or secondary failure.

Initial dose and dose adjustment: The initial dose is 1 mg once a day. The daily dose can be increased if needed.

It is recommended to increase the dose gradually according to the results of blood glucose monitoring, such as 1 mg 2 mg 3 mg 4 mg 6 mg every 1 2 weeks, up to 8 mg in individual patients.

Patients with well-controlled diabetes mellitus generally have a dose of 1 4 mg per day, and only a few patients have a dose greater than 6 mg per day.

Duration of medication: The duration of the medication is determined according to the patient's lifestyle. Generally, it can be taken once a day, and it is recommended to take it before breakfast, or before the first main meal if you skip breakfast. In particular, don't forget to eat after taking the medicine.

Follow-up dose adjustment: With the improvement of diabetes symptoms and the increase of insulin sensitivity, the need for this drug should also be gradually reduced, and the dose should be reduced or even stopped in time to avoid hypoglycemia. The ** of this drug generally needs to be carried out for a long time.

Change from other oral hypoglycemic drugs to this drug: This drug has no exact dose relationship with other oral hypoglycemic drugs. When using this drug instead of other oral hypoglycemic drugs, the recommended starting dose is 1 mg per day, even when the maximum dose of other oral hypoglycemic drugs is being used.

The dose increase of this drug should be done in accordance with the requirements of the above "initial dose and dose adjustment method". Considering the efficacy and duration of previous hypoglycemic drugs, it is necessary to interrupt** to avoid hypoglycemia caused by the cumulative effect of drugs.

Glimepiride tablets are indicated for non-insulin-dependent diabetes where blood sugar control is not satisfactory for food, exercise** and weight loss. When taking glimepiride tablets, it should be taken immediately before or during a meal. Irregular or absent meals with glimepiride tablets** can cause hypoglycemia.

Possible symptoms of hypoglycemia include headache, extreme hunger, nausea, vomiting, weakness, and drowsiness. Sleep disturbances, irritability, aggressive behavior, inattention, slowed reactions, depression, confusion, visual impairment, incoherent speech, aphasia, tremor, paresis, sensory disturbances, dizziness, feelings of helplessness, loss of self-control, delirium, cerebral convulsions, drowsiness and loss of consciousness, and even coma, shallow breathing and bradycardia.

In addition, signs of adrenergic reverse regulation, such as diaphoresis, clammy cold, anxiety, tachycardia, hypertension, palpitations, angina, and arrhythmias, may also be present. Symptoms of a severe hypoglycemic episode can be similar to that of a stroke.

Immediately after taking carbohydrates (sugars) orally, the symptoms of hypoglycemia described above almost completely disappear. Artificial sweeteners are ineffective in hypoglycemia. It has been learned from other sulfonylureas that hypoglycemia may persist despite initial successful control of hypoglycemia**.

In patients with severe or long-term hypoglycemia, regular amounts of sugar can only temporarily control symptoms, requiring urgency** and, in some cases, hospitalization**.

In the initial ** phase, the starting dose of glimepiride is 1 2 mg once a day, administered at breakfast or at the second main meal. For diabetic patients, there is no fixed dose of glimepiride or any other glucose-lowering drug, and fasting glucose and glycosylated hemoglobin must be measured periodically to determine the small effective dose of the patient's medication; Glycosylated hemoglobin levels are measured to monitor the patient's ** effect.

Glimepiride tablets are oral drugs, as for the dosage of the drug, it also depends on the severity of the disease, the age of the patient's friends, the sensitivity to the drug, etc. After all, the doctor is a professional, and when it comes to the dosage of drugs, especially for children, it should be left to the doctor to decide.

Please strictly follow the instructions and the doctor's prescription, and it is recommended that you consult professionals in the relevant field in detail and follow the doctor's instructions! Due to seasonal, regional and other reasons, glimepiride tablets** may fluctuate to a certain extent, but the fluctuation is not large. Glimepiride tablets should therefore actually be takenCardinal Health's PharmacyThe actual selling price of each store shall prevail.