What is ankylosing spondylitis?

Ankylosing spondylitis (AS) is a disease in which inflammation of the sacroiliac joints and spinal entheses is the main symptom. It is strongly associated with HLA-B27. Certain microorganisms, such as Klebsiella, share antigens with the susceptible person's own tissues and can elicit an abnormal immune response.

It is a chronic inflammatory disease characterized by fibrosis and ossification of the fibrous tissues of the fibrous ring of the intervertebral disc and its vicinity, as well as joint rigidity. Ankylosing spondylitis is a chronic disease with the spine as the main lesion, involving the sacroiliac joints, causing spinal rigidity and fibrosis, resulting in different degrees of eye, lung, muscle, and bone lesions, and is an autoimmune disease. Thank you!

Compulsory spondylitis is a very painful disease, if you can't self-discipline, it has to be very uncomfortable, and the plaster will be maintained, and one of my colleagues is that he doesn't dare to ha, and his waist has become stiff You say it starts again This is not the right to suffer from the disease. Therefore, people must be careful not to damage the lumbar spine, so the rate of not ** is very low.

Ankylosing spondylitis, known as ankylosing spondylitis in medicine, refers to a chronic autoimmune disease that occurs in the spine, axial bones and large joints of the limbs, and is characterized by fibrosis and ossification of spinal entheses and joint anklosis as the lesions, and is a relatively serious chronic progressive disease.

Ankylosing spondylitis has a strong insidiousness, mostly occurs in young men, and the early symptoms are often mild, only the symptoms of stiffness and soreness in the lower back area, and in severe cases, the hip area and low back pain are obvious at night, and it is difficult to get up, and even low-grade fever, weight loss, fatigue and other symptoms will occur. In the early stage, due to the mild disease, the clinical manifestations are not specific, and some patients cannot be identified**; With the progression of the disease, the patient develops special lesions of the sacroiliac joint, and begins to invade the spine, hip joint and other important parts, at this time, the patient gradually develops limited movement and rigidity of the lumbar spine and other joints, affecting normal life. In the scope of modern medicine, ankylosing spondylitis is treatable, and with sports** and drugs**, the patient's physical pain can be greatly reduced and the quality of life can be improved.

Ankylosing spondylitis is a chronic inflammatory disease, belonging to rheumatological immune diseases, the main lesion sites are in the spine-sacroiliac joints, peripheral joints, and other places, but there are very few, serious ones will lead to severe spinal deformity and spinal rigidity, so it is called ankylosing spondylitis.

The incidence rate in China is about 4:1 between men and women, and the onset of women is relatively slow and mild. Ankylosing spondylitis occurs mainly in young men, usually between the ages of 11 and 31, with a peak of 20 to 30 years of age, and is rare at other ages.

**It is not too clear, it is currently believed that it is related to genetics, infection, environment, and immunity, and the incidence of general men is relatively high, with a certain familial cluster. The expression of the HLA-B27 gene is highly correlated with familial spondylitis, but not HLA-B27 positive necessarily has ankylosing spondylitis.