What causes myasthenia gravis?

Myasthenia gravis is a very serious neuroimmune disease, mainly a clinical manifestation of gravitational muscle weakness, which generally affects the normal life activities of patients, and some patients are difficult to take care of themselves. So what do you know about such a terrible myasthenia gravis?

Myasthenia gravis is an autoimmune disease caused by dysfunction of transmission at the neuromuscular junction, which generally means that the muscles do not accept the signals transmitted by neurotransmitters, and in a little more specially, the antibodies produced by the signals transmitted by neurotransmitters at the muscle junctions.

Myasthenia gravis is an immune disease that is not common in daily life, so many patients who have been diagnosed with this disease are afraid to hear about their disease, so do you know the common sense of myasthenia gravis? Experts said that in fact, we don't have to worry too much, as long as we are serious, there is hope. Let's take a look at what causes this disease.

1. The patient's autoimmune system is an important cause of this disease, and it is also the most important. According to experts, myasthenia gravis is an autoimmune disease, so the patient's immune system must be abnormal. Clinical studies have found that many immune indicators in patients with myasthenia gravis are abnormal, and the clinical symptoms disappear after **, but the abnormal immune indicators do not change, which may be the instability of the disease.

2. Heredity is also a very important cause of myasthenia gravis. According to our clinical research, many autoimmune disease studies have found that they are not only related to major histocompatibility antigen complex genes but also incompatible antigen complex genes, such as T cell receptor, immunoglobulin, cytokines, apoptosis and other genes.

3. There are also some external factors for myasthenia gravis, mainly including external environment and diet. All of them belong to myasthenia gravis**. Clinical findings show that certain environmental factors such as environmental pollution cause a decrease in immunity; Immune dysfunction due to overexertion; Viral infections or the use of drugs such as aminoglycoside antibiotics or d-penicillin amine induce certain genetic defects.

The causes of myasthenia gravis are divided into two categories: one is congenital hereditary, which is very rare and has nothing to do with autoimmunity; The second group is autoimmune diseases, which are the most common. The cause of the disease is not clear, but it is generally thought to be related to infection, drugs, and environmental factors. At the same time, 65% to 80% of patients with myasthenia gravis have thymic hyperplasia, and 10% to 20% have thymoma.

Myasthenia gravis is an autoimmune disease at the neuromuscular junction. Nerve impulses travel to nerve endings, which release a transmitter called acetylcholine. Acetylcholine binds to acetylcholine receptors on the muscle muscle membranes, giving instructions to the muscles to contract, relax, or contract and relax harder.

After autoimmune disorders, antibodies to acetylcholine receptors in the postsynaptic membrane will be produced, so that acetylcholine receptors will be destroyed and reduced, and the receptors bound to acetylcholine will be reduced, and the instructions to the muscles will be reduced, and the impulses of the muscles will also be reduced, which can cause muscle weakness, and in severe cases, it can cause muscle atrophy, which is myasthenia gravis. The exact cause of the autoimmune disorder is not well understood, and further research is needed.

The cause of myasthenia gravis is not clear, and it is generally divided into two categories, one is congenital inheritance, which is basically very rare. The second type is autoimmunity, which is the most common, and it is now generally believed that it is related to infections, drugs, and environmental factors.

Myasthenia gravis is an acquired autoimmune disease in which the transmission of nerves and muscles is impaired. Its main clinical characteristics are that the whole body or part of the skeletal muscle is easily fatigued after activity, and the symptoms are reduced after rest and cholinesterase inhibitors**, and the causes of this disease are as follows: First, severe infection.

For example, severe pneumonia, sepsis, etc. Second, he endured major surgeries and trauma. Thirdly, severe mental trauma and blows.

Fourth, systemic diseases. Fifth, excessive fatigue. Sixth, pregnant and childbirth patients.

In some patients, severe disease can even induce myasthenic crisis.

It has also been linked to malnutrition.

Myasthenia gravis can also occur if nutrition cannot keep up, and the nutritional factor is also myasthenia gravis**, and some families living in poverty often cause myasthenia gravis due to malnutrition.

Associated with food poisoning, viral infections.

With the rapid development of society, environmental problems are becoming more and more serious, and the body's immune function will decline if you live in a relatively polluted environment for a long time, and the reduced immunity cannot prevent virus infection. The food we eat and the water we drink are very polluted, and when infected with thymovirus, the immune function is reduced, leading to myasthenia gravis.

With heredity there is. Genetic factors are also linked to myasthenia gravis, and according to research, if one or both parents suffer from myasthenia, the next generation will be exposed to myasthenia. It is recommended that patients with myasthenia gravis in the family should pay attention to it in a timely manner, stabilize the condition, and avoid heredity.

Associated with excessive fatigue.

Overwork and mental stress can cause this disease, some patients often suffer from playing computer games for a long time, playing mahjong after the disease, studies have found that some overworked patients, prone to myasthenia gravis.

Environmental factors are one of the causes of myasthenia gravis, such as environmental pollution that causes decreased immunity; Immune dysfunction due to overexertion; There is also geneticity that causes myasthenia gravis.