What exactly is myasthenia gravis, what is myasthenia gravis?

Hello, myasthenia gravis is a chronic disease in which the nerve-muscle junction transmission is impaired due to autoimmunity. It is mainly caused by damage to acetylcholine receptors on the postsynaptic membrane of the neuro-muscle junction and conduction block. The main manifestations are that the affected muscles are easily fatigued, which is aggravated after activity, relieved after rest, and mild in the morning and heavy in the evening.

The prognosis of this disease is good, and a small number of patients have complete remission after **.

Myasthenia gravis (MG) is an autoimmune disease caused by dysfunction of transmission at the neuromuscular junction, which is clinically manifested as partial or systemic skeletal muscle weakness and fatigue, which worsens after activity and is relieved by rest. The prevalence is 77,150,100,000, with an annual incidence of 4,111,100 million. The prevalence is greater in women than in men, about 3:

2. It occurs in all ages, and children are mostly 1 to 5 years old.

**: The causes of myasthenia gravis are divided into two categories, one is congenital hereditary, which is very rare and has nothing to do with autoimmunity; The second group is autoimmune diseases, which are the most common. The cause of the disease is not clear, but it is generally thought to be related to infection, drugs, and environmental factors.

At the same time, 65% to 80% of patients with myasthenia gravis have thymic hyperplasia, and 10% to 20% have thymoma.

Patients with myasthenia gravis often feel soreness and discomfort in the eyes or limbs, or blurred vision, fatigue easily, and fatigue worsens in hot weather or menstrual cramps. As the disease progresses, skeletal muscles become significantly fatigued and weak, which is characterized by muscle weakness that worsens after exertion in the afternoon or evening and decreases after getting up or resting, a phenomenon called "morning light and twilight heaviness".

1.Patients with myasthenia gravis can have skeletal muscles throughout the body affected and may have the following symptoms.

1) Dropy eyelids, blurred vision, diplopia, strabismus, and inflexible eye movement.

2) Indifferent expression, wry smile, large tongue, difficulty in arthria, often accompanied by nasal voice.

3) Weakness in chewing, choking on drinking water, and difficulty swallowing.

4) Weak neck, difficulty in raising the head, weakness in turning the neck and shrugging the shoulders.

5) Difficulty in raising arms, combing hair, going up stairs, squatting, and getting on the bus.

It is possible to take traditional Chinese medicine for the symptoms** Chinese medicine ** has a very good effect.

Myasthenia gravis is a group of autoimmune diseases that cause problems in the transmission of nerves and muscle junctions. The cause of its disease is not very clear, and it may be related to infection, immune disorders, environment, etc. It is more common in females than males, and is more common in children between the ages of one and five.

Since the disease is a nerve and transmission problem, its manifestations are mainly related to the gradual decrease in muscle strength, and "light in the morning and heavy in the evening" is its unique symptom. According to different clinical manifestations, it can be divided into six types.

The first type, the ocular muscle type, simply put, means that the muscles of the eye are mainly affected by an upper eyelid droop, the eye can not move at will, and then there can also be strabismus, diplopia, etc.

Type 2 mild generalized type, as the name suggests, the whole body muscle strength is slightly impaired, in addition to eyelid weakness, there will also be weakness in the limbs, can not walk for a long time, difficulty in raising the head, daily life such as combing hair, mild restriction on going up and down the stairs, and the symptoms of light morning and twilight are more obvious.

The third type, in fact, is the second type of gradual aggravation, in addition to the above manifestations, there are choking cough after drinking and eating, difficulty swallowing, hoarseness or loss of voice, etc., gradually aggravated, slowly involving the ventilator, and dyspnea.

Type 4, the fourth is also an exacerbated version of the systemic type, and the disease progresses rapidly, and soon becomes difficult to breathe, or even unable to breathe on its own.

The fifth type, the delayed severe type, is that the condition is not effectively controlled, the progression is relatively slow, and the progression is slow, and it takes more than 2 years for dyspnea to appear.

The sixth type, the amyotrophic type, is extremely rare.

Myasthenia gravis, although it is called myasthenia gravis, but in fact, the prognosis is okay, most patients can be effectively controlled, and some can even be healed spontaneously.

Li Jianjun, Shijiazhuang City: Myasthenia gravis is a chronic disease caused by the impaired transmission of neurotransmitters at the neuromuscular junction of patients, resulting in muscle weakness and contraction.

Patients may suddenly have difficulty swallowing, choking on water, difficulty eating, and in severe cases, death due to suffocation;

If it does not heal for a long time, severe cases can cause organ failure due to complicated muscular dystrophy.

Myasthenia gravis is an autoimmune disease that, like other autoimmune diseases, is caused by a disorder of the body's immune system that disrupts the body's normal "order". Myasthenia gravis is the attack of acetylcholine receptors in the postsynaptic membrane of the neuromuscular junction by autoantibodies, and when the function of this important receptor is abnormal, it will directly affect the normal conduction and action of neuromuscles. Disorders of the body's immune system are generally related to environmental factors, infection factors, drug factors, etc., but the specific causes of myasthenia gravis are not clear.

What is myasthenia gravis, myasthenia gravis is simply a chronic disease, an autoimmune disease, which produces antibodies, mistakenly thinks that the acetylcholine receptors in their bodies are foreign invaders, destroys the receptors' ability to accept acetylcholine, makes the number of receptors insufficient, and B choline cannot function normally, resulting in weak muscle contraction. When the respiratory system is affected, a crisis of myasthenia gravis occurs. There are usually ophthalmosis types, such as simple ophthalmosis and generalized types, and the generalized type has ptosis, pupil covering, and a positive fatigue test.

More than 10% of people have tumors in the thymus, most of which are benign, and some people think that it is the immune center, and after surgical resection, they can receive good clinical results. Patients often have muscle weakness, swallowing weakness, weak and weak eyes with open and closed eyes, light in the morning and heavy in the afternoon, relieved after rest, including the movement of the muscles of the limbs, doing physical work is very difficult, gradually worsening, and finally affecting breathing and causing a crisis.