What are the precursors of ankylosing spondylitis? What are the hazards?

Mandatory spondylitis prefers the male population, especially young men aged 16-25 years. The early symptoms of this disease are hidden and can be easily overlooked. However, most diseases are generally detected early, and the earlier the detection, the higher the success rate.

Ankylosing spondylitis is an autoimmune disease, which is currently unknown, and may be related to the genetic environment, immune function, etc. Most patients present with sacroiliac joint pain and pain in the lower back and other spine pains.

What are the precursors of ankylosing spondylitis?

Ankylosing spondylitis has a slow onset and mild systemic symptoms, but may cause fatigue and reduced signs in the early stage, or symptoms such as nausea and fever may occur. Some people with ankylosing spondylitis may develop sciatica. If the lesion affects the costal joints, there may also be limited or loss of chest expansion during breathing and intercostal neuralgia.

What are the dangers of ankylosing spondylitis?

1. Ankylosing spondylitis invades the sacroiliac joint, and then gradually affects the lumboar, thoracic and cervical vertebrae due to the development of the disease, resulting in blurring of the facet joint space, disappearance of fusion, osteoporosis and destruction of the vertebrae, and ossification of the ligaments, which eventually leads to spinal stiffness. To relieve the pain, the patient prefers to adopt a position with the spine flexed. Over time, a curved hunchback can form throughout the spine that protrudes backwards, which is one of the consequences of ankylosing spondylitis.

2.In the long term, skeletal fusion hunchback deformity can lead to limited neck movement, which gradually worsens and forces you to bend. If the spine, hips, and knees are stiff in the deformed position, the patient is often bedridden; If he is forced to walk, he must also use crutches or benches; If the spine, hips, and knees are stiff in a functional position, the patient can still stand upright and walk slowly using the rotation of the body and ankle dorsiflexion and plantar flexion.

3.Eye and other organ lesions, some patients with ankylosing spondylitis may have ocular pigmentitis in the process of the disease, unilateral or bilateral alternation, reversal, and even visual impairment. The cardiovascular and respiratory systems can also be affected.

4.Low back pain, low back pain is also one of the symptoms of ankylosing spondylitis, when the disease occurs, the spine is connected to the lumbar spine, and inflammation can cause pain and discomfort in the lower back, and the movement of the lower back is severely limited. The pain level will be significantly worse at night, it will be difficult to turn over during sleep, and the quality of sleep will be easily affected.

Although there is no specific drug for ankylosing spondylitis, it can relieve pain and spinal stiffness in the early stage, inhibit the development of symptoms, and prevent deformities, and in the later stage, it is necessary to correct deformities and complications.

It will cause the body to be very thin, it will also lead to loss of appetite, edema, and backache in ordinary life, resulting in very inconvenient movements, and movement disorders, which will seriously affect their normal life.

Generally, the spine will be particularly painful, and then there will be a particularly strong feeling of stiffness, which will also affect normal movement, and then it will also lead to the complete disappearance of the curvature of the waist, which will lead to excessive hunchback, rickets, and will also hurt the cervical spine, will also hurt the spine, and will also affect normal walking.

I think people are very vulnerable, because people can get all kinds of diseases, and some of them are very serious, and if they are serious, they can even cause you to lose your life. What are the effects of ankylosing spondylitis? What do you know?

I don't know too much about this problem, so I also looked up relevant information on the Internet, ankylosing spondylitis is more serious, that is, it will cause the entire spine to be deformed, which may affect everyone's ability to work. At this time, you will no longer be able to do some heavy work, and you will not be able to do some physical work at ordinary times, so you can only cultivate at home.

And this disease can also cause people to break bones, because patients with ankylosing spondylitis are in chronic inflammation for a long time, so it will always damage everyone's energy, and it will lead to a decline in labor, and will also lose the ability to take care of themselves, because if you get this disease, it will cause you to feel physical pain. Therefore, it will lead to a decrease in activity, so it will lead to osteoporosis, and at this time, the patient may also be prone to fractures. As a result, the disease can be very painful and can lead to many complications that can lead to a significant loss of quality of life.

Therefore, we must pay attention to related problems in our lives, and a small number of patients may also have kidney and heart damage. Although this disease will not lead to direct death, this disease may make everyone feel particularly painful, and it is also a kind of torture and injury to everyone's psychology. If you really have these problems, then it is recommended that you go directly to the doctor and actively accept the doctor's **.

What I learned is that this disease is caused by doing physical work for a long time, and eventually it will cause pain, and it will also lead to deformities, deformities, and deformities, which will make the bones very fragile and make the bones very loose.

Resulting in inflexibility in the lower back, great pain, work and life are affected, easy to fall, and fragile bones, these are all effects, and I also learned that this disease is formed due to long-term fatigue.

It will have a great impact, because it will affect the development of bones, lead to a decline in physical fitness, lead to a decrease in resistance and immunity, and also affect normal life, which may lead to the loss of self-care.

There is still a lot to understand, the impact is particularly serious, it may lead to people with hunchback deformity, scoliosis, and hip deformity, which will cause the thoracic rib joint to be affected, which will affect a person's figure.

It will have a very serious impact, it will affect normal life, it will affect the health of the body, it will also affect the development of bones, and then it will also lead to a decrease in resistance and immunity, and in severe cases, it is likely to lead to the loss of self-care.

Answer: Ankylosing spondylitis (AS) is a disease characterized by inflammation of the sacroiliac joints and spinal entheses. For 16-25-year-old youth, especially young men.

Ankylosing spondylitis generally has an insidious onset, and there may be no clinical symptoms in the early stage, and some patients may show mild systemic symptoms in the early stage, such as fatigue, weight loss, long-term or intermittent low-grade fever, anorexia, mild anemia, etc. Due to the mild disease, most patients cannot be detected early, resulting in a delay in the disease and the loss of the best opportunity.

Ankylosing spondylitis is a very serious heterogeneous joint disease that causes a range of diseases to:

1) Cardiac lesions occur in a small number of aortic fibroids, pericarditis and myocarditis.

2) Ocular lesions 25% of AS patients have conjunctivitis, iritis, ocular pigmentitis or uveitis, the latter of which may occasionally be complicated by spontaneous anterior chamber hemorrhage. Iritis is easy to **, the longer the disease, the higher the incidence, but it has nothing to do with the severity of spondylitis, it is common in people with peripheral joint disease, and a few can precede spondylitis.

3) Ear lesions In AS patients with chronic otitis media, the extra-articular manifestations were significantly more than those in patients without chronic otitis media.

4) Pulmonary lesions are manifested as sputum production, wheezing, and even hemoptysis, and may be accompanied by reversible pneumonia or pleurisy.

5) Nervous system lesions due to spinal rigidity and osteoporosis, it is easy to cause cervical dislocation and spinal fracture, thus causing spinal cord compression. If spondylodiscitis occurs, it can cause severe pain. In the later stage of AS, cauda equina syndrome can be violated, resulting in radicular pain in the lower limbs or buttocks, loss of sensation in the sacral nerve distribution, decreased Achilles tendon reflexes, and motor dysfunction such as bladder and rectum.

6) Amyloidosis is a rare complication of AS.

7) Kidney and prostate lesions.

Hello! Ankylosing spondylitis is a chronic progressive inflammatory disease that mainly affects the spine, sacroiliac joints and large joints of the limbs. Most of the cases are in men between the ages of 16 and 30.

When the disease occurs, it can produce strong pain in the neck, shoulder, lower back, numbness and soreness of the limbs, muscle atrophy, the body can not walk straight, can not lie flat, the patient is in pain, and some even cause serious complications such as neurodermatitis, colitis, ulcer disease, etc.

The most serious consequence of ankylosing spondylitis is disability, so ankylosing spondylitis must be detected early, carried out correctly and effectively!

For patients in the early stage, as long as you choose the right and effective **method** in time**, you can still recover very well, how to do it**, you can communicate with me in detail! Hope it helps!

Ankylosing spondylitis is a rheumatological and immunological disease, pain, limited mobility, painful joint curvature, multi-organ complications, joint fusion, disability, and inability to take care of oneself.

Ankylosing spondylitis is a chronic inflammatory disease that mainly affects the sacroiliac joints, spinal bony processions, paraspinal soft tissues, and peripheral joints, and can be accompanied by extra-articular manifestations. The main clinical manifestations are lumbar, back, neck, hip, hip pain and joint swelling and pain, severe cases can occur spinal deformity and joint ankonosis, it is recommended to go to (Wuhan Tianren Hospital of Traditional Chinese Medicine) to see, Professor Luo Yongyan can directly find him.

Hello, ankylosing spondylitis is an immune disease, ankylosing spondylitis can produce a variety of complications, as the disease increases, it can lead to ear lesions, heart disease, eye lesions, kidney lesions, etc. Therefore, with ankylosing spondylitis, it is important to control the condition and prevent complications. It is recommended to choose a regular professional hospital for comprehensive examination, conduct a comprehensive examination of pathology, and gradually realize the removal of inflammation and pain, the removal of joint restrictions, the repair of bones, and the regulation of immunity, so as to achieve a comprehensive and anti-professional effect and restore the life of a normal person.

The early symptoms of ankylosing spondylitis are not too obvious in many cases, and the pain of jujube in the waist and sacral part will be accompanied by a stiffness in the lower back mostly, which is obvious in the morning and can be reduced after activity. There are also cases of knee, ankle, heel, and sciatica. Therefore, if a young man aged 12 to 30 years has persistent or intermittent pain in the lumbosacral and hip joints, accompanied by a feeling of stiffness in the lower back and limited bending and squatting, or unexplained pain in the small joints such as the calcaneus, thoracic cord, costal vertebrae, temporomandib, shank, and metatarsophalangeal joints, you should consider whether you have ankylosing spondylitis.

In fact, the diagnosis of this disease is not difficult, and most patients can be diagnosed with just a clear pelvic radiograph. Early diagnosis and early diagnosis are very important to improve the rate of disability and reduce the rate of disability. Oh.

Ankylosing spondylitis is a chronic, progressive inflammation of the spine that affects the sacroiliac joints, articular processes, nearby ligaments, and large joints near the trunk, resulting in fibrous or bony rigidity and deformity, and is a distinct disease. Its most significant changes are fibrosis and bony rigidity of the joints, which are hereditary.

At present, many patients and their families are very concerned about the occurrence and development of ankylosing spondylitis, how can it be prevented? Many experts and scholars in China and abroad are studying the disease, because only by knowing the onset of the disease can the disease be controlled. However, there is no clear answer so far, but a large number of studies have found that the onset of the disease is mainly related to the following factors:

1. Autoimmunity:

Ankylosing spondylitis is an autoimmune disease in its own right. Serum complement is found to be elevated in 60% of patients with ankylosing spondylitis, with IgA-type wet factor in most cases, markedly elevated serum C4 and IgA levels, and circulating immune complexes (CICs) in serum, but the nature of the antigen is not determined. These phenomena suggest that immune mechanisms are involved in the pathogenesis of the disease.

2. Infection: Recent studies have suggested that the incidence of ankylosing spondylitis may be related to infection. Ebrimger et al. found that the detection rate of Klebsiella pneumoniae in the stool of patients with ankylosing spondylitis was 79%, compared with 30%

According to statistics from Mason et al., 83% of male patients with ankylosing spondylitis were complicated with prostatitis, and some authors found that about 6% of patients with ulcerative colitis were complicated with ankylosing spondylitis; Other reports have also confirmed that the incidence of ulcerative ulceritis and localized enteritis is much higher in patients with ankylosing spondylitis than in the general population, so it is speculated that ankylosing spondylitis may be related to infection.

3. Heredity: Genetic factors play an important role in the pathogenesis of ankylosing spondylitis. According to epidemiological investigations, the positive rate of HLA-B27 in patients with ankylosing spondylitis is as high as 90% and 96%, while the positive rate of HLA-B27 in the general population is only 4% 9%. The incidence of ankylosing spondylitis in HLA-B27 positive patients is about 10% 20%, while the incidence of ** disease in ordinary people is 1 2, a difference of about 100 times. It has been reported that the risk of ankylosing spondylitis in a group of relatives is 20 to 40 times higher than that of the general population, and the prevalence rate of first-degree relatives in ankylosing spondylitis in domestic surveys is 120 times higher than that of the normal population.

The incidence of ankylosing spondylitis in the relatives of healthy HLA-B27-positive patients is much lower than that of relatives of patients with HLA-B27-positive ankylosing spondylitis. All these suggest that HLA-B27 is an important factor in the pathogenesis of ankylosing spondylitis.