How is plague diagnosed? How to get the plague

Laboratory tests show elevated peripheral leukocytes, elevated mesogranulocytes, and decreased or absent eosinophils. Etiological examination, lymph node aspiration fluid, blood, cerebrospinal fluid, sputum and other smears or cultures can detect Y. pestis. Serology, patient antibody acute titer 1:

or a 4-fold increase in titer during the course of the disease confirms the diagnosis.

Specific classification manifestations: (1) Glandular type: mainly acute lymph node inflammation, mainly in the groin and armpit, lymph nodes are red, swollen, hot, and painful, and the patient can be forced to be in a special posture due to pain, and the lymph nodes can be adhered to or purulent with the surrounding tissues, and the wound heals slowly.

2) Pulmonary type: cough, shortness of breath, purple lips and complexion, chest pain, foamy blood sputum, hemoptysis, and the whole body can be highly purple due to dyspnea and lack of oxygen at the end of life.

3) Sepsis type: rapid coma, extensive bleeding throughout the body, complicated by diffuse intravascular coagulation, shock.

4) Mild plague: manifested as irregular low-grade fever, mild systemic symptoms, much like upper respiratory tract infection, regional lymph nodes can be swollen and tender.

5) Other types: ** type, red and swollen at the invasion of Yersinia pestis, with black scabs, easy to necrosis and ulcers, similar to anthrax; meningeal type, high fever, headache, severe vomiting, irritability, altered mental status; intestinal type, with vomiting, abdominal pain, diarrhea, a feeling of falling, and mucinous bloody stools; ocular shape, conjunctival hyperemia, swelling, and abundant purulent discharge; Pharyngeal type, tonsillar hyperemia, edema, exudate, cervical lymphadenopathy.

It's really sick, and there are still people who want to create a plague, is there something wrong with their brains? There are still many epidemic areas in China. Most of the rats in the endemic area are bacterial, so you take one back, dissect it, and culture it, and Yersinia pestis grows well on normal medium.

Then look at it under a microscope. Perform a selective culture and then pick up colonies on the medium. You suck it in, it's OK, and after a short incubation period, it quickly becomes ill.

Then you don't go to the hospital**, the pneumonic plague is 100% dead. You will be able to go west. If you want someone else to get.

I really don't know how much you hate people and use such a shady method. It's just sick.

If it appears suddenlyAny of the symptoms such as fever, chills, lymph node pain, cough, coughing up blood or bleeding, should seek immediate medical attention, can be passedComplete blood count, isolation and identification of bacteria, serology, polymerase chain reaction (PCR) testingand so on to confirm whether there is plague.

1. Clinical manifestations of plague

The main clinical types include bubonic plague, pneumonic plague, and septicaemic plague, and other types of plague such as ** plague, enteric plague, and tonsil plague are relatively rare.

1. Bubonic plague

The main clinical manifestations are high fever, chills, nausea and vomiting, headache and limb pain, facial flushing, conjunctival hyperemia, ** mucosal bleeding spots, etc. It mostly manifests as swollen inguinal lymph nodes, axillary lymph nodes and cervical lymph nodes, and develops rapidly, mostly unilateral, and the lymph nodes quickly suppurate and burst after a week.

2. Pneumonic plague

The clinical manifestations are mainly acute onset, chills and high fever, headache and chest pain, shortness of breath, purple lips, cough, cough up mucus or bloody frothy sputum, and death is often due to heart failure, hemorrhage, and shock.

3. Sepsis plague

The clinical manifestations are mainly high fever and chills, confusion, coma, followed by septic shock, disseminated intravascular coagulation, extensive bleeding and necrosis.

This is a Class A infectious disease, commonly known as No. 1 disease, and if you get a disease, you will become famous throughout the country.

The incidence is extremely low!

The diagnostic criteria for plague are:

1.Epidemiological data Traveled to plague-endemic areas within 10 days prior to the onset of illness, and had a history of contact with plague agents or patients.

2.Clinical manifestations Sudden onset, high fever, severe systemic toxicity symptoms and early failure, bleeding tendency, lymphadenopathy, pulmonary involvement or sepsis.

3.Laboratory tests Detection of pathogenic bacteria and/or detection of serum-specific F1 antibodies from lymph node aspirate fluid, pus, blood, etc.

Hamsters are not pathogen vectors, and if a hamster is infected with plague, he himself will die quickly.

If you have plague, it must not have been transmitted to you by a hamster.

Hamsters are safer than dogs and cats.

Hello, plague is a relatively serious infectious disease, it is best to go to the hospital to be vaccinated against plague and rabies if bitten by rats.

Plague is a virulent infectious disease caused by Yersinia pestis bacillus, including bubonic plague, pneumonic plague, and plague sepsis. The mode of transmission is: bubonic plague is transmitted by flea bites, which is manifested by swollen lymph nodes, severe pain, and high fever; Pneumonic plague is transmitted through the respiratory tract by feeding infected animals or respiratory droplets of sick people, manifesting as high fever, cough, and bloody sputum; Septicaemic plague plague is usually a secondary infection.

Personal plague is conditional, and the most basic ones are the following two aspects: 1. The area where it is located is the foci of plague; 2. The source of the epidemic is located in the active period, and there are plague rats.

1.Routine check-ups.

The total number of white blood cells and neutrophils increases, and the decrease in red blood cells and hemoglobin varies depending on the degree of bleeding, and platelets may decrease. People with enteritic forms may have blood or mucus and bloody stools.

2.Isolation and identification of bacteria.

Blood, pus, sputum, cerebrospinal fluid, lymph node puncture fluid and other materials were collected and sent for testing. The general examination procedure includes microscopic examination, culture, plague phage lysis test, and animal experiments, referred to as the four-step test, all four of which can confirm the diagnosis of plague.

3.Serologic tests.

1) Fluorescent antibody staining microscopy (IFA) has the advantages of rapidity, sensitivity and high specificity, but there are false positives or false negatives.

2) Indirect hemagglutination (IHA) is the mixing of erythrocytes sensitized to plague-specific antigens (or antibodies) with the material being tested for the examination and determination of plague antibodies (or antigens). It is a rapid, sensitive, and highly specific serological diagnostic method. It can check not only live and dead bacteria, but also soluble antigens as well as contaminated and spoiled materials.

It was widely promoted in China in the 70s and is one of the most effective rapid diagnostic methods.

3) Radioimmunoprecipitation assay (RIP) is sensitive and highly specific, which is not only one of the most ideal methods for plague surveillance and source detection, especially for the recourse diagnosis of mild and atypical cases, as a supplement to the deficiency of IHA, it has certain practical value.

4) The improved method of hemagglutination of staphylococcal A protein (SPA-IHA) has a higher detection rate than indirect hemagglutination, and the method is more simple, which is suitable for basic experiments in the field.

4.Polymerase chain reaction (PCR) assay.

Diagnosis can be made within a few hours and is a rapid and highly specific method. It is of great significance for plague surveillance, early clinical diagnosis and molecular epidemiological investigation.

5.Other detection methods include ELISA and radioimmunoassay.