Does anyone know the contamination characteristics of biopharmaceuticals and chemical pharmaceutical

Pharmaceutical industry wastewater can be divided into four categories according to the product.

1) Wastewater from the production of synthetic drugs. The water quality and quantity of this kind of wastewater vary greatly, and mostly contain substances that are difficult to degrade and microbial growth inhibitors; Chemical synthesis pharmaceutical wastewater has a high COD concentration and high salt content, and the main pollutants are organic substances, such as fats, benzene organic compounds, alcohols, esters, petroleum, ammonia nitrogen, and sulfides.

and various metal ions, etc.

2) Biological fermentation method of pharmaceuticals (production of antibiotics.

and vitamins) production wastewater. It is divided into extraction wastewater, washing wastewater, vitamin C production wastewater, and other wastewater, among which the organic matter concentration of fermentation filtrate, extracted extract, distillation kettle residue, adsorption waste liquid, catheter waste liquid and other wastewater is very high, and the COD can be as high as 5000-80000mg L; The concentration of SS in wastewater can reach 5000-23000 mg L; There are antibiotic substances that are difficult to biodegrade and have antibacterial effect in wastewater, and when the antibiotic concentration is greater than 100mg l, it will inhibit the activity of aerobic sludge.

3) Chinese patent medicine.

Production wastewater. Its water quality fluctuates greatly, COD can be as high as 6000mg L, BOD can reach 2500mg L, mainly contains natural organic substances;

4) Washing water and rinsing water for various drug production processes. It mainly comes from chemical residues, raw material washing water and floor washing water.

Biopharmaceutical contamination is actually not as much as chemical pharmaceutical pollution, because after biopharmaceuticals, the rest of the waste generally has another purpose, but we don't know how to use it, and the things that come out of chemical pharmaceuticals are very toxic.

Bacilli, pigment-producing bacteria and fungal spores are common in outdoor air; There are more microorganisms in indoor air than outdoors, and common pathogenic bacteria in indoor air include Neisseria meningitidis, Mycobacterium tuberculosis, hemolytic cocci, diphtheria bacillus, pertussis bacillus, etc.

Pathogenic bacteria in water, such as typhoid bacillus, dysentery bacillus, Vibrio cholerae, leptospira, etc., mainly come from human and animal faeces and pollutants.

What are the common microbial contaminations of pharmaceutical formulations.

This question is up to me, it takes a little time to type, so please be patient

Bacilli, pigment-producing bacteria and fungal spores are common in outdoor air; There are more microorganisms in indoor air than outdoors, and common pathogenic bacteria in indoor air include Neisseria meningitidis, Mycobacterium tuberculosis, hemolytic cocci, diphtheria bacillus, pertussis bacillus, etc. Pathogenic bacteria in water, such as typhoid bacillus, dysentery bacillus, Vibrio cholerae, leptospira, etc., mainly come from human and animal faeces and pollutants.

A: The environmental pollution that may be caused by the biopharmaceutical process is mainly determined by the toxicity and loss (discharge) of raw materials, intermediates, and end products. The environmental pollution that may be caused includes ambient air pollution and wastewater discharge pollution; Noise pollution may also be present.

According to the actual situation of pollution, relevant solutions are designed in detail.

This is the need to do product link analysis according to the product process, and put forward targeted treatment measures, which is not the same, and needs to do environmental impact assessment.

It is mainly biological contamination of water and air, that is, bacteria or viruses. The water treatment is 80 degree insulation and sterilization, and the air is filtered by filter.