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The pancreas includes both exoand endocrine substances. Exocrine secretions secrete pancreatic juice, while endocrines are the many clumps of pancreatic cells scattered in the pancreas, called islets, that secrete secretions such as insulin. The main function of insulin is to regulate the absorption, utilization and conversion in the body, such as promoting the synthesis of glycogen from blood glucose (glucose in the blood) and accelerating the breakdown of blood sugar.
Diabetes occurs when the body's insulin secretion is insufficient. Diabetics can do it with insulin**, and there is no oral preparation for insulin; It is a protein composed of amino acids, which is a protein, and the stomach is the place where the protein is initially digested, so if insulin is taken orally, it will be absorbed by the digestive system and cannot play a role.
Therefore, it can only be injected, and it must not be taken orally.
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At present, insulin oral drugs have not been approved by the State Food and Drug Administration. I guess if you want to buy it, you may have to go directly to the inventor or the development company. If they're willing to help you, you can get it.
In fact, oral insulin is completely available and processed through technology. I heard that there are already some sold in Hong Kong, ** it seems to be 10 yuan.
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Oral insulin is "unreliable." It's better to still inject it. Remember to eat after the injection to prevent possible hypoglycemia. Hypoglycemia can be dangerous in people with diabetes.
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Most of the ones that can be taken orally are secretin.
I also use pancretin-promoting drugs with hypoglycemic drugs.
It is also necessary to control the diet and exercise.
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Why does insulin need to be injected instead of taken directly.
Because insulin is a protein peptide drug, oral administration will be digested and decomposed into amino acid fragments by digestive juices in the intestine, losing the integrity and function of insulin, affecting its hypoglycemic effect, so at present, insulin can only be injected, not oral.
Can insulin be taken orally and why?
Insulin, first of all, it is a protein, and there is pepsin in the human stomach, after oral administration, insulin is decomposed by the stomach egg liter white enzyme, and then does not bite the original effect.
Why can't insulin be taken orally, please tell me.
The results of oral insulin preparations have shown that if the drug molecule is properly encapsulated, it can play a protective role and promote the absorption and utilization of the drug, resulting in biological effects. Oral insulin has been clearly shown to lower blood glucose and increase plasma insulin concentrations.
Biology Question Why can't insulin be taken orally?
Insulin slippage is a protein that is digested orally and cannot be used.
Insulin can only be injected and cannot be taken orally for reasons.
Oral insulin is ineffective because when insulin is taken orally, the body's digestive juices destroy the insulin and make it ineffective. Its efficacy can only be guaranteed by absorption into the bloodstream.
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People who love sugar, or who eat a lot of sugar, are prone to insulin in the body not working properly. That's where the ** comes in. Let's talk about oral insulin.
1.First: there is no oral insulin, but there are drugs that also have the ability to lower blood sugar, but a doctor's prescription is required.
You don't need to take insulin for a long time, take hypoglycemic drugs at the same time as insulin, and then diet, you can't eat too much rice, only half a bowl, and you can eat vegetables, but don't eat too greasy, pay attention to elevated cholesterol.
2.Second: insulin is a special protein, if taken orally, it is digested into polypeptides, and it loses its physiological effect.
Diabetes mellitus is caused by insufficient insulin secretion leading to high blood sugar and metabolic disorders, which is difficult with general drugs, and can only be temporarily controlled by taking Western medicine to lower blood sugar or injecting insulin.
3.Third: Due to the unique therapeutic effect of insulin-based hypoglycemia, as a hypoglycemic biochemical drug, it has been used in **diabetes for 75 years since 1923, and has been the first choice for patients with insulin-dependent diabetes.
Because insulin is a protein peptide drug, it can be degraded by proteolytic enzymes in the gastrointestinal tract and is not absorbed, so oral administration is ineffective.
Precautions. So far, there is no oral insulin on the market. Whether it will appear in the future depends on the development of medicine. Patients can take hypoglycemic drugs to recuperate.
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Insulin cannot be taken orally at this time. Because after insulin is taken orally, gastric acid will be broken down by gastric acid and destroy the structure, therefore, oral insulin cannot play a role in lowering blood sugar.
The most effective way to control blood sugar is to give the patient subcutaneous insulin injections**. In addition, it is difficult to slow down the effect of insulin on blood sugar, so insulin cannot be taken orally.
Insulin should not be cryopreserved and should be avoided from too high, too low, and too vigorously shaking. The type of insulin preparation, injection technique, injection site, patient reactivity differences, and insulin antibody formation can all affect the onset time, intensity, and duration of insulin action.
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Relevant experts said that "oral insulin" is unreliable, and diabetic patients must not use it indiscriminately, and should standardize the use of drugs under the guidance of doctors.
Insulin is a "peptide hormone", commonly known as "protein", which is digested by proteases in the stomach after oral administration, thus losing its effect.
According to experts, the research on insulin at home and abroad has not stopped, and scientists have never given up on changing the insulin dosage form, but non-injectable insulin such as "oral insulin", "nasal spray insulin", "sublingual insulin" and so on are still dreams, and many key technical problems are still not solved. In particular, there are large individual differences in the absorption capacity of the human digestive tract, which is significantly different from the operability of subcutaneous injection to absorb insulin.
At present, the "oral insulin" advertised by some domestic pharmaceutical and health products advertised does not exist at all, and many of them are just health products. There is no health supplement that can truly ** diabetes.
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For diabetes, insulin is not used, and only injections are effective.
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