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Meijer syndrome is an idiopathic dystonic disorder characterized by blepharospasm and oral-mandibular dystonia. It is necessary to pay attention to dietary conditioning and balanced nutrition. Take rest and avoid strenuous exercise.
Oral medications** or pacemaker surgery** can be used. Able to control symptoms and slow progression, but not**.
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Meijer's syndrome is a group of extrapyramidal disorders first described by French neurologist Henry Meige. The main manifestations are blepharospasm, ororomandibular dystonia, and facial dystonia-like involuntary movements. Meige first reported Meijer syndrome in 1910, and since then, it has been referred to as Brueghel's syndrome, blepharospasm, ororomandibular dystonia, etc.
1. A large number of literature reports that botulinum toxin (BTX) is effective for this disease, but it is expensive and has ***, and its use is limited. Symptomatic dry eye syndrome is the most common, along with dysphagia, ptosis, dyspnea, photophobia, diplopia, etc.
2. Oral medication.
1) Antipsychotics Clozapine has been observed to be effective for this condition, and its *** has sedation and orthostatic hypotension, etc., and must be assisted by a hematology monitor when used.
2) Cholinergic receptor blockers The use of Antan (6 mg d) can reduce the frequency of blepharospasm attacks.
3) Dopamine blockers.
4) Anti-epileptic drugs.
5) Others Some people think that melatonin can be effective for this disease based on the effect of melatonin in regulating dopaminergic, cholinergic, and 2 amino acids.
6) Drugs that are ineffective against the disease: levodopa aggravates the condition.
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Meijer syndrome generally includes medications or surgery, Meijer syndrome may cause dysphagia, and may also cause dyspnea, and may also manifest as photophobia rock finches or above the eyelids of the jujube mask to droop.
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The voice of many patients with Meijer syndrome, for this disease has run a lot of places, any method has been tried without effect, some people are exhausted, no confidence, are tortured by Meijer syndrome, hit confidence, since then doubt various methods, suspect large hospitals, suspect small clinics, suspect Chinese medicine, suspect Western medicine, Meijer syndrome as an incurable disease has gradually entered people's lives, patients have photophobia, frequent blinking, eyes can not open, mouth twitching, affecting their own life, Social, serious and even tongue biting, teeth grinding, difficulty swallowing, dyspnea, viscera failure, so no matter how many times you have failed, how many disappointments, but you still have to have a glimmer of hope, the experience of failure has passed, a key can only open a lock, and there will be a beautiful future waiting for you, because if you don't ** this disease will slowly develop very serious, so since it has happened to your body, don't hesitate, delay, delay will not only aggravate the development of the disease, but also spend more money, We have studied Meijer syndrome for many years, and there are more patients with good recovery, more experience, and according to the feedback of most patients, the effect is very good, so I believe that the majority of patients will recover as soon as possible like other patients.
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How to ** Meijer syndrome. The ** of Meijer syndrome includes the drug ** and the botulinum toxin **, and the drug ** can be selected as follows: nth.
1. Anticholinergics, the maximum dose of trihexyphenidyl can be given, which can control symptomsnth.
2. Diazepam or clonazepam can be effective for some patientsnth.
3. Haloperidol, phenothiazines or tetrabenazine can be given, and when the effective dose is reached, there is a possibility of inducing mild parkinsonism, so caution should be used when using itIn addition, patients with Meijer syndrome, if the drug ** is not effective, botulinum toxin type A can be given**, and multi-point injection can be done subcutaneously around the cleft eye, and some patients have better results, and the efficacy can be maintained for 3-6 months, and repeated injections are effective.
The main symptom of Meijer syndrome is dystonia of the head and face, so the vast majority of patients first manifest themselves with spasm of the eyelids, feeling that the eyes are constantly blinking and unable to open the eyes. There is another type of patient, the bilateral mouth corner involuntary movement, and another type of patient is the patient with neck muscles, constantly twisting the neck, about a frequency or idle for a few minutes, or even a few seconds before the neck twists, like this is the head and face stage dystonia. The last type is a combination of multiple eyes, including blepharospasm, ororomandibular spasm, and spasm of the neck muscles.
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