The parameters for the pathological diagnosis of the breast gland are as follows, what do these para

ER is estrogen and PR is progestogen, and these two positives indicate that the patient is sensitive to hormones ** and can be used hormones**; If C-ERBB-2 is positive, it means that the prognosis is not very good, or it is easy to **, or it is easy to metastasize, and if you are negative, it means that the prognosis is better; ki67 refers to the growth index of cells, the higher the cell activity, the worse the prognosis; p53 refers to the intact or absent myoepithelium, and if negative, it indicates that the tumor cells have broken through the myoepithelial infiltrative growth.

ER(+)PR(+) indicates the need for endocrine**, if it is a premenopausal patient, it is recommended to take tamoxifen, if it is in perimenopause or has just ended chemotherapy, resulting in menstrual disorders or amenorrhea, and the menstrual status cannot be confirmed, the blood estrogen level can be checked to determine the menstrual status. If you are a postmenopausal patient, it is recommended to take an aromatase inhibitor. C-ERBB-2(-) does not need to be targeted**.

The ER(+)PR(+)C-ERBB-2(-)KI67 index is about <1%, which together indicates that Luminal A breast cancer is the one with the best prognosis. p53(-) has no clinical guidance at present. The formulation of chemotherapy plan also needs to be formulated according to the size of your mass, the status of lymph nodes, vascular cancer thrombus, histological grade, and the formulation should also be based on your own general condition, whether it is accompanied by heart disease, diabetes, etc.

In addition, if breast-conserving surgery is done or there is metastasis in the lymph nodes, radiotherapy is required after chemotherapy.

Analysis: Hello, from the results of this examination of the patient you mentioned, it is the result of immunohistochemistry after breast cancer surgery, which is used to judge the best aspects of the disease and the prognosis.

Suggestions: At this time, if the patient's physical condition is fine, chemotherapy should be done, but the chemotherapy is larger, and there is a certain amount of harm to the body.

These immunohistochemical results mean that this case of breast cancer is typical of hormone-dependent breast cancer. The effect of endocrine ** is very good. The prognosis is good.

Chemotherapy is still done.

1. It should be said that it is not serious.

2. If there are no clear symptoms, such as breast tenderness before and after menstruation, you can have regular check-ups and do not take medicine first.

3. Lymph node display, that is, lymph node enlargement can be seen when doing ultrasound, but there are many reasons for lymph node enlargement, in addition to breast cancer metastasis, there are other possibilities such as upper limb infection, so don't worry about it now. Also, if you have a test during your menstrual period, the menstrual period may affect the results, so if you want to be serious, it is recommended to repeat the test one week after the end of menstruation.

4. Which sentence can be seen to be breast hyperplasia? "The glandular echo is coarse, and it is a grid-like echo of high and low encounters".

ER and PR represent estrogen receptors and progesterone receptors, respectively, (+ patients have a better prognosis and can be endocrine**, (-patients have a poor prognosis, and endocrine ** is not recommended; C-ERBB-2 is a proto-oncogene, expressing transmembrane tyrosine kinase growth factor receptor, C-Erbb-2 positive patients have a poor prognosis, trastuzumab**, sensitive to anthracyclines, easy to tamoxifen resistance, negative patients have a good prognosis; E-Cd is a calherin that is mainly expressed in normal tissues, and studies have shown that patients with (-) have a higher chance of implantation or metastasis, so the prognosis of your + is relatively good. Ki-67 is a nuclear protein expressed in the G1, S, M, and G2 phases of the cell cycle, which is considered to be a more accurate indicator of growth and proliferation score, representing the proliferation rate of tumor cells, the higher the prognosis, the worse the prognosis, and your 15% is not high.

Analysis: Hello, for your case, it is clear from the examination results that there is metastasis, and regular chemotherapy and re-examination are recommended.

Suggestions:

N-type: This type shows high signal in both T1Wi and T2Wi images; PL type: In this type, most of the images of T1WI and T2WI are hyperintense of fat, and the ductal tissue is shown as hypointensity; Type P2:

On the T1Wi and T2Wi images, the high and low signals account for almost half of the total. DY type: On the TWI and T2WI images, the low signal is almost indistinguishable. The Wi and T2Wi images are almost uniform and the catheter structure is almost indistinguishable in the low signal area.