Can nephrotic syndrome be cured? Are there any sequelae?

The question of whether nephrotic syndrome can be cured is more complicated. The etiology, pathogenesis, duration of the disease, no effect, and outcome may vary among the types. The same pathological type with the same clinical presentation is not necessarily the same; The pathological types that usually manifest mild are not 100% mild or easy to treat.

2 6 children, minimal lesion type ( type) can account for 95%; In patients over 60 years of age, membranous nephropathy accounts for 40%. The use of standard amounts of hormones in children with primary nephrotic syndrome** can often achieve satisfactory results, and sequelae can no longer occur. Mesangial nephrotic syndrome** is more difficult and mainly protects kidney function.

The response of focal segmental sclerosis type ** is poor, and the ineffective case can reach 50% to 60%. Moreover, compared with young people, the performance of long-term use of hormones in large doses is more obvious, so doctors will weigh the pros and cons and decide whether to use hormones.

Whether patients with nephrotic syndrome have sequelae or not depends mainly on the type of pathology, and some types are more likely to turn into chronic renal insufficiency or renal failure.

Experts from Qingdao Jingkang Traditional Chinese Medicine Kidney Disease Hospital pointed out:

What mistakes do people with nephrotic syndrome make when using hormones?

Patients and doctors are most worried about the use of hormones, so patients with nephrotic syndrome are most likely to make two mistakes when using hormones: first, the doctor is not properly arranged, the initial dose is small, the dosage is insufficient, and the condition cannot be relieved quickly; After taking hormones, the dose is reduced too quickly, and the maintenance medication is too short; The second is that the patient does not take the medicine properly. Many patients are afraid of hormones (obesity, acne, full moon face), so they do not follow the doctor's instructions and reduce the dosage by themselves, which is self-defeating.

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Nephrotic syndrome is a possibility. Current research has shown that nephrotic syndrome is an immune-related disease. Improving immunity, everyone may be relatively unfamiliar, in layman's terms, it is the body produces a lot of things that attack the kidneys, this kind of thing we call antibodies.

Antibodies attack the permeable membrane of the glomeruli, resulting in increased permeability and loss of a large amount of protein, resulting in nephrotic syndrome.

Nephrotic syndrome and chronic glomerulonephritis have many similarities in terms of mechanism. However, it has a very big difference from chronic glomerulonephritis, that is, nephrotic syndrome has the possibility of **, while chronic glomerulonephritis has no ** possibility. This gives hope to many people with nephrotic syndrome.

As mentioned earlier, nephrotic syndrome is an immune-related disease, so conventional antibiotics are not effective in reducing inflammation for this disease, usually with hormones and immunosuppressants**. The more commonly used hormones are methylprednisolone and prednisone, while the more commonly used immunosuppressants are cyclophosphamide. Nephrotic syndrome is divided into 5 types, each of which has a different sensitivity to both drugs.

Among them, the minimal lesion type and the mild mesangial hyperplasia type are more sensitive to hormones, and the possibility of ** is very high. The other three types are not very sensitive to the above drugs, and the likelihood is relatively small. Therefore, we say that nephrotic syndrome is the most likely, but not all of them.

If you have nephrotic syndrome, you can start with hormones** for two to three months. If the effect is not good, it is recommended to perform renal puncture as soon as possible to determine the pathological type, and then decide the next step, which can improve the rate and remission rate.

I am a netizen from China.com, named Zhao Xinghua, female, 46 years old this year, born in 76, a post-70s generation. I got this disease in 2016, and this disease tormented me for two years, and these two years were the most difficult time of my life. I went to Yiling Hospital in 2019 after the Lunar New Year**, when there was still light snow in the sky, and the weather was very cold, even if I was wearing a thick down jacket, I still felt very cold, I remember it very clearly.

Zhu Zhaoming, the chief doctor in the hospital, was the one who was ** for me, and I was cured after being there for about a month. It's 2022 now, and it's been two years since I was sick, and I haven't had it, and I've benefited for life.

Nephrotic syndrome, whether it is primary or secondary, is not sure that the current scientific methods can completely treat it completely.