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Diabetic patients have several major misconceptions about medication:
1.When you see what medicine others take, you should take it yourself. Diabetes mellitus is different from other diseases, according to the patient's body type, hyperglycemia type, whether there are other diseases and age, etc., type 1 diabetes can only use insulin plus metformin, -glycosidase inhibitors, while type 2 diabetes can choose different types of hypoglycemic drugs, different patients use different drugs.
2.Blindly superstitious imported medicines, expensive medicines, and new medicines. In fact, there is no good or bad medicine for diabetes, only suitable and unsuitable.
3.Fearing that metformin will hurt the kidneys, they refuse to take it, and metformin does not cause any damage to patients with good kidney function.
4.Some patients do not take their drugs on time and take them when they want to, resulting in poor blood sugar control.
5.Many patients forget to take the medicine after taking it, and many patients forget to take the medicine when they should take it, and then make up it afterwards, which is easy to cause blood sugar fluctuations.
6.When taking hypoglycemic drugs, only follow the doctor's instructions and never read the instructions, because the situation of each patient is different, and the patient should still read the instructions by himself after getting the drug to avoid adverse reactions.
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Combination of pain drugs should be avoided, as the combination of drugs will increase the amount of drugs. Rush to lower blood sugar and take a large amount of medication. In a hurry, frequent dressing changes. There is also drug dependence and neglect of non-drugs**.
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Do not eat candy while taking medication. The medicine must be soaked in warm water, and do not mix Chinese medicine with Western medicine. Be sure to eat before taking your medicine.
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Many diabetic patients only take medication without controlling their diet, change drugs for a long time, and usually ignore as long as their blood sugar is not high, and they will feel insulin dependent.
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With the incidence of type 2 diabetes mellitus (T2DM) increasing year by year, the situation of diabetes prevention and control in China is very severe. In the continuous progression of T2DM, most patients need to use a combination of drugs to achieve glycemic control, and most patients with T2DM are middle-aged and elderly, often with other diseases such as cardiovascular disease and infection. In other words, the combination of drugs for T2DM patients is not only limited to hypoglycemic drugs, but also includes antihypertensive drugs, lipid-regulating drugs, antiplatelet drugs, and even other drugs such as antibiotics.
Therefore, clinicians need to pay attention to the interaction between drugs while controlling sugar.
The dangers of drug interactions should not be underestimated.
Drug-drug interaction (DDI) refers to the phenomenon that when two or more drugs are used simultaneously or sequentially, the magnitude, duration and even nature of the action of one drug are significantly changed or adverse drug reactions are produced by other drugs or chemicals1. The incidence of DDI increases with the variety of drugs used, such as about 4% when 2-5 drugs are taken at the same time; When 6-10 medications are taken at the same time, the incidence is as high as 20%2. At present, there are many types of hypoglycemic drugs commonly used in clinical practice, and the metabolic pathways of these drugs in the body are different, and the mechanism of action is also different, which will cause unique interactions when combined with other drugs.
Based on the effect on the ** effect, DDI can be classified as beneficial and harmful. Moderate enhancement of ** effects or lessening adverse effects are beneficial, and vice versa is a harmful interaction3, e.g., hypoglycaemic events have been reported when hypoglycemic drugs are combined with quinolone antibiotics4.
In addition, special attention should be paid to those at high risk of developing DDI, such as those requiring long-term drug maintenance** (arrhythmias, epilepsy), patients with organ insufficiency or failure (hepatic and renal insufficiency, congestive heart failure), or older patients with multiple chronic diseases2.
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