Ask about thalassemia Urgently

Hello. Thalassemia, also known as marine anemia, is a group of inherited hemolytic diseases caused by partial or complete inhibition of the synthesis of one or more of the globin chains of hemoglobin.

It is divided into marine anemia and marine anemia. Decreased or absent globin chain synthesis caused by a defect in the globin gene is called marine anemia.

Judging from the man's blood test results, the increase in HbA2 is more than and the HBF is slightly increased, which does not rule out the possibility of marine anemia heterozygous, and it is recommended to do further genetic diagnosis!

Effect on offspring: Marine anemia is inherited in an autosomal dominant manner. If the woman has been diagnosed as heterozygous for thalassemia genes, if the male is also heterozygous for thalassemia, there is a 1 4 chance that the offspring will be inherited from both parents to the marine anemia gene, which is homozygous (severe anemia); 2 4 may be inherited from one parent to the marine anemia gene, which is heterozygous (mild); There is also a 1 4 probability that it is completely normal.

If the male's genetic test results are normal, the offspring 1 2 may be heterozygous (mild); 1 of 2 may be completely normal.

Thalassemia. I don't know it, but I know that when I was playing the Age of Discovery, there was not much left of the crew of my ship.

1.You are iron deficient. Serum ferritin is low and high in transferrin, which is a textbook iron deficiency, and it does not happen overnight.

In the case of girls, the possible cause is an unreasonable diet, low intake of red meat, or excessive blood loss over a long period of time (menstrual hemorrhoids). If it is a man and there is no obvious gastrointestinal disease and blood loss, it is necessary to pay attention to it and go to the hospital for further examination. Note that both men and women have blood loss, and iron supplementation without eliminating the source of blood loss is useless, and anemia will only get worse.

2.HBF is high, and thalassemia is highly suspected, while thalassemia is not excluded. Mild and moderate are possible, and genetic testing for thalassemia is recommended.

To sum up, you are iron deficient (diagnosed) + thalassemia (very likely) coexisting. It is advisable to go to the hospital for further testing of these two areas** (iron deficiency).

At ordinary times, you can eat more iron-rich foods, such as pork liver, beef liver, chicken and duck liver, pork loin, pork belly, beef kidney, beef lung, beef juice, egg yolk powder, dried whitebait, dried yellow croaker and other meat dishes, and you can also eat more spinach.

In addition, in addition to diet, you can insist on 2 cups of Xueying tea every day, which can combine blood and qi supplementation, and replenish both qi and blood.

Thalassemia major:

Patients with this type of hemoglobin below 6 g dl, severe lack of normal hemoglobin, and if there is no blood supplementation, the following symptoms will appear: paleness, tiredness, loss of appetite, low immunity (susceptibility to infections, etc.), slow growth and hepatosplenomegaly, etc. In the long run, it is easy to lead to underdevelopment, bone deformation and heart failure, thus shortening the life expectancy.

Therefore, regular blood transfusions are required.

Thalassemia intermedia:

This type of patient has hemoglobin of 6 9g dl, generally presents with paleness, slightly enlarged spleen, no other obvious symptoms, normal growth and development, and no regular blood transfusion. However, blood transfusions are required in cases where anemia may worsen, such as infection, drug misuse, pregnancy, etc.**.

Thalassemia minor.

This type of patient is a carrier of the gene for thalassemia and has only minor problems with the function of making hemoglobin. Generally, there are no clinical manifestations, and the physical condition is relatively normal.

Thalassemia type A:

This type of thalassemia has a low incidence in China, is mostly severe, and occurs in the fetal period, dies in the womb at the end of pregnancy, or dies from severe anemia and hypoxia shortly after birth.

Thalassemia type:

The incidence of this type of thalassemia in China is mostly mild anemia and a small proportion are moderate anemia. Severe patients are usually born normally, and symptoms of anemia usually do not develop until three to six months postpartum.

Mild anemia or asymptomatic disease, usually found during family history.

Most patients with moderate anemia survive into adulthood. Such patients are pale, easily tired, loss of appetite, low immunity (susceptibility to infection, etc.), slow growth and hepatosplenomegaly. It is more common in children, and there is no abnormality at birth, and only a few months after birth does the child slowly appear pale, dull expression, dementia-type face, stunted growth, anemia, hepatosplenomegaly, etc.

The common symptoms of thalassemia major are: anemia within a few days of birth, progressive aggravation of hepatosplenomegaly, jaundice, and dysplasia, and its special manifestations are: large head, widening of the eye distance, saddle nose, forehead protrusion, cheek protrusion, its typical manifestation is a buttock-like head, long bones can be fractured.

Skeletal changes are caused by hyperhematopoiesis of the bone marrow, widening of the bone marrow, and thinning of the cortex. A small number of patients develop a thoracic mass between the ribs and spine, and gallstones and leg ulcers may also be seen. Common complications include acute pericarditis, secondary hypersplenism, and secondary hemochromatosis.

Thalassemia is a group of inherited anemias caused by hereditary globin production disorders and is classified as severe, moderate, mild, and very mild.

Guidance: This disease is a hereditary disease, and if the anemia is not severe, it can be not. There is no special method for this disease, mainly blood transfusion, and at the same time take some deferoxamine, vitamin B12 folic acid and so on.

Thalassemia is a genetic disorder that is divided into thalassemia and thalassaemia. The severity varies depending on the type and amount of thalassemia genes carried. Thalassemia minor has no anemia or slight anemia, is not severe, and can live like a normal person, and pregnant women who find thalassemia mild do not need **.

Severe thalassemia requires repeated blood transfusions to correct severe anemia.

Thalassemia is an autosomal recessive disease, and if the husband is normal, the child born from the average thalassemia may be completely normal or a carrier like you. Don't worry about this.

In addition, thalassemia may be inherited to children, so it is recommended that you take a pregnancy test during pregnancy to see if it is possible.

Globin dyspoietic anemia, formerly known as thalassemia, also known as marine anemia, is a group of inherited hemolytic anemia disorders. Anemia or pathological condition caused by the absence or insufficiency of one or more globin chains in hemoglobin due to inherited genetic defects. Due to the complexity and diversity of genetic defects, the type, number and clinical symptoms of the deficient globin chain are highly variable.

They are named and classified according to the type of globin chain that is lacking and the degree of deficiency.

The disease is widely distributed in many parts of the world, and Southeast Asia is one of the most common areas. It is more common in Guangdong, Guangxi, and Sichuan in China, and there are sporadic cases in provinces and regions south of the Yangtze River, but it is rare in the north.

You can go to the hospital for a check-up.

Then you're really thin enough, think about how to gain weight, how to eat more.

It is normal to get dizzy when you stand up after squatting. For everyone, yes, but I forgot why, the teacher used to talk about it.

As for anemia, it is not necessarily thin, for example, do you often get sick, usually have a feeling of dizziness, you will feel very uncomfortable when you move a little, if you have these symptoms, you should eat more stew, buy something to make up, and feel that dietary therapy is better.

Thalassemia is mainly treated with iron removers and blood transfusions**. If it is to be **, then a bone marrow transplant will be used. Thalassemia is mainly caused by a disorder of globin production and is a family genetic disorder in which thalassemia is mainly administered by iron removers and blood transfusions.

If it is to be **, then a bone marrow transplant will be used. Thalassemia is mainly caused by a disorder of globin production and runs in families. Thalassemia is mainly treated with iron removers and blood transfusions**.

If it is to be **, then a bone marrow transplant will be used. Thalassemia is mainly caused by a disorder of globin production and is a familial genetic disorder that can easily lead to hepatic metabolic disorders, severe liver failure, and systemic hemolytic changes if the disease is more severe, which can be life-threatening at any time. The first choice for moderate to severe thalassemia is hematopoietic stem cell transplantation, but the cost is very high, and there will be a series of rejections after the transplant, which is difficult to overcome.

If two men and women with the same type of thalassemia have children, the possible outcomes are:

Because the baby inherits two normal genes (one for each parent), the baby is completely normal (1 in 4 times).

Babies inherit a normal gene from their father (or mother) but a defective gene from the other parent, resulting in thalassemia traits (2 in 4 years of grandchildren).

Babies inherit two thalassemia genes from both parents (one for each parent). The result is that the infant has thalassemia moderate or major (1 in 4 years).

Symptom. Symptoms of thalassemia major in early childhood:

Fatigue (feeling tired), weakness.

Pale or yellow skin (as if in jaundice).

Enlargement of the spleen and liver, protruding abdomen.

Urine dark pants in color.

Facial bone deformity and poor health.

Diagnosis. Details:

1.Endocrine** can help, but it's unlikely to be completely normal.

2.It is advisable to check her blood iron level and try to avoid excessive iron intake if it is too high. Hemoglobin should be checked regularly and, if necessary, transfusions. Use antimalarial drugs with caution.

3.People with severe thalassemia often show signs of depression and anxiety, but your girlfriend is not in her 20s and is not fine, so it is unlikely that she has severe thalassemia. It is advisable to determine the severity of thalassemia (genetic testing), which is of great help in determining whether thalassemia is caused or whether she has a bad temper.

4.Again, from your narrative it seems likely that she is a moderate thalassaemia. However, there is no genetic test result, and the results cannot be determined.

Patients with moderate thalassemia generally do not have a great impact on their life expectancy, but have symptoms such as splenomegaly, dysplasia (especially in the absence of **), susceptibility to infection, and hemolysis. But symptoms in patients with moderate thalassemia vary widely. Some people may have nothing, while others have some of the above problems.

If it's mild thalassemia, which means that what you're talking about has nothing to do with thalassemia, then there's no problem.

5.People with thalassemia do not receive blood donations. If you don't have enough hemoglobin yourself and you may need a blood transfusion, don't donate blood.

This is a genetic disease, which cannot be cured, and it will be passed on to children, and if you want children in the future, it is better to change women as wives.