Is nephrotic syndrome the more severe the puffiness, the more severe the condition?

Different types of kidney diseases show different degrees of edema, such as acute nephritis can cause edema, nephrotic syndrome has more and more serious edema, some chronic nephritis syndrome and acute tubular necrosis oliguric phase will also appear renal edema, while chronic renal tubular disease, chronic interstitial disease, pyelonephritis, etc. generally do not occur edema. In some patients, although the inherent cells and tissues of the kidneys have been destroyed, and the glomerular filtration rate is also very low at this time, because the renal tubular reabsorption capacity is worse than the glomerular filtration rate, there is no water and sodium retention, so the patient can have no symptoms of renal edema or the edema is very mild. It can be seen that although the basis of renal edema is sodium and water retention and water migration to the interstitial space, there is no direct relationship between the degree of edema and the degree of renal damage due to the different emphases of edema.

Advice: The above is just a doctor.

Yes, edema is caused by a large amount of proteinuria, high levels of albumin in the blood and in the urine.

If the nephrotic syndrome is severe, it is definitely necessary to have hormones**.

Hello, it's not that the more severe the edema, the worse the condition.

About one-third of patients with kidney disease will have edema, but some patients with kidney disease are more lucky, such as minimal lesions, membranous nephropathy, which on the surface seems to be menacing at the time of onset, and it is a large amount of proteinuria that exceeds the day at every turn, and the urine protein will even exceed 10g a day, accompanied by edema of the lower limbs, and sometimes accompanied by edema of the upper limbs, face, abdomen and even generalized edema. However, as long as the kidney function is not impaired, hormones, immunosuppressants, traditional Chinese medicine, etc. can be used for anti-inflammatory, anticoagulation, lipid lowering, diuretic, urine protein can be reduced, and various symptoms can basically be recovered.

However, some types of nephropathy without edema, such as mesangial proliferative nephritis (including IgA nephropathy), are generally not obvious, but it should be noted that urine protein is not easily reduced after medication, and the edema is not obvious and is difficult for patients to detect. Some patients can detect the disease by gross hematuria, but many asymptomatic patients are kept in the dark.

In addition, patients with edema usually have better outcomes. In fact, in addition to crescent nephritis and membranoproliferative glomerulonephritis, in primary glomerular diseases, edema is a good thing.

Edema is a typical "signal" in the early stage of chronic kidney disease, which often occurs on the face, eyelids, lower limbs, ankles, and in severe cases, increased ascites and even generalized edema.

The amount of nephropathic edema depends on the degree of edema. If the patient has only mild edema of the ankles and eyelids and no other specific symptoms, it is not necessary to actively diuretic to reduce the swelling. However, if the patient has high blood pressure, pleuroabdominal effusion, or even heart failure, chest tightness and shortness of breath, diuresis and swelling are required, and even dialysis drainage is required to control blood pressure and reduce the burden on the heart.

These measures are only designed to address the symptoms of superficial edema. It is advisable to identify the root problem of kidney disease, and in the case of primary glomerular disease, it may be necessary to use hormones to ** the underlying problem of kidney disease.

Edema caused by nephrotic syndrome is caused by low protein, and edema caused by decreased plasma albumin caused by loss of urinary protein: edema caused by nephritis is caused by sodium and water retention, and the mechanism is different, often the edema of nephrotic syndrome is more severe than that of nephritis, but it does not mean that the disease is serious, it is recommended to seek medical attention in time, because different nephropathy methods are different, under the guidance of doctors, the edema will slowly subside.

Patients with this disease lose large amounts of plasma protein in the urine, resulting in hypoprotein sliding blood and decreased plasma colloidal osmotic pressure, resulting in interstitial fluid accumulation, which is a central link in the pathogenesis. Secondly, due to the decrease in secondary blood volume and effective circulating blood volume, the secretion of aldosterone and anti-noise diuretic is increased, and the reabsorption of sodium and water by the distal convoluted tubule and collecting duct increases, resulting in sodium and water retention, which is also an important factor in edema.

Hello, swollen feet in patients with kidney disease is actually a kind of edema, which is divided into two types: nephrotic edema and nephritic edema.

1. Nephrotic edema: It usually occurs in primary glomerulonephropathy and nephrotic syndrome caused by various reasons.

The pathogenesis of this edema is mainly due to the decrease in plasma colloidal osmolality: in nephropathy, a large amount of urine protein causes hypoproteinemia, which leads to a decrease in plasma colloidal osmotic pressure, which increases the fluid filtration in the capillaries, significantly reduces the body fluid from the interstitial **, and finally forms edema. Effective volume depletion:

Plasma extravasation reduces effective blood volume, decreases natrihormone secretion, and increases sodium reabsorption in renal tubules, further aggravating water and sodium retention and aggravating edema.

2. Nephritic edema: mainly seen in acute nephritis, or some rapidly progressive nephritis, chronic nephritis and other glomerular diseases.

The pathogenesis of this edema is due to the fact that when acute nephritis occurs, some patients develop congestive heart failure due to increased blood volume, hypertension and other reasons, which aggravates water and sodium retention; The increased hydrostatic pressure in the capillaries causes the fluid in the capillaries to move too much into the interstitial space and cause edema.

For the edema of kidney disease, patients should pay attention, during the edema, should reduce the intake of sodium, potassium and other substances, otherwise it will cause very serious consequences, so patients should treat edema correctly.

Patients with chronic renal insufficiency and kidney disease should not drink more water. Patients with chronic renal insufficiency or renal failure are unable to excrete water and salt normally due to the gradual loss of kidney function; People with kidney disease lose a lot of protein in the urine because of the loss of protein in the body, which reduces the osmolality of the blood, and if you drink too much water, the edema will become more severe.

Most patients with acute nephritis present with loose eyelids, facial tissues, and may develop eye or facial edema in the morning. However, if edema is more pronounced, generalized edema may occur, and lower extremity edema is more common. In the most severe cases, edema can occur in the upper limbs and even the trunk.

If the edema is more severe, a serosal effusion may occur, so the location of the edema varies depending on the severity of the disease.