Human blood albumin is accidentally frozen into ice, can it still be used If it is used is harmful.

Wasted. If you can't use it, the protein has been denatured and will kill you.

It can't be used, and the storage temperature of human blood albumin does not exceed 30 degrees, but it's a pity.

Storage method】 Storage method: It should be avoided to be stored in 2-8. Freezing is strictly prohibited.

Precautions] 1 The liquid medicine is turbid, precipitated, foreign matter or the bottle is cracked, the cap is loose, expired, etc.

2. After this product is opened, it should be infused at one time, and should not be divided or given to the second person;

3. If the patient is found to have an unpleasant reaction during the infusion, the infusion should be stopped immediately;

4. Those with obvious dehydration should be rehydrated at the same time;

5. It is strictly forbidden to freeze during transportation and storage.

Dosing instructions] 1All dilution and injection operations of this drug should be carried out in accordance with strict disinfection procedures. After opening, it should be used once, and should not be divided or used by a second person; It cannot be used again after exposure for more than 4 hours after opening.

2.The lyophilized preparation can be dissolved with 5% glucose injection or sterilized water for injection, generally using 10% albumin solution, which should be dissolved within 15 minutes. When preparing 20%-25% high-concentration albumin solutions, the dissolution time is longer.

3.The rate of intravenous infusion should not exceed 2ml per minute. In case of allergic reaction, the drug should be stopped immediately, and if necessary, another batch of the drug can be changed.

4.When using this drug, the condition must be carefully observed to prevent the patient's central venous pressure from rising. Particular attention should be paid to patients with cardiac insufficiency or other cardiac disorders, as too rapid volume increase can lead to an acute circulatory load or pulmonary edema.

5.A hypertonic solution of 15% to 25% albumin is generally not appropriate in patients who have been dehydrated unless they are supplemented with adequate fluids.

6.Human blood albumin is mainly to supplement albumin, such as insufficient energy intake, often metabolized and burned, can not achieve the purpose of increasing blood albumin level, so it is best to supplement enough calories before using albumin.

7.This drug cannot be combined with vasoconstrictors; However, it can be used in combination with glucose injection or saline. Patients with kidney disease should not dilute this drug with normal saline.

Summary. The main thing is that it cannot be stored at high temperatures (high temperatures denature proteins).

After the protein is denatured, it is fed into the body,1Allergies – severe and fatal; 2.Nothing worked.

Albumin requires cryopreservation, but it is not completely freezing.

The main reason why albumin cannot be frozen is that after freezing, albumin needs to be dissolved into a solution before it can be introduced into the body, and during the thawing process, protein denaturation may occur due to significant changes in temperature.

If the albumin can avoid the process and phenomenon of freezing during the freezing process, and does not need to be dissolved during injection, it can be frozen.

Can human albumin be transfused after thawing?

Hello, I am helping you to inquire about the relevant information and will reply to you immediately.

The main thing is that it cannot be stored at high temperatures (high temperatures denature proteins). Protein denaturation after plexus envy, input into the human body, 1Allergies – severe and fatal; 2.

Albumin without any effect requires cryopreservation, but it is not completely unfrozen. The main reason why it cannot be frozen is that after freezing, albumin needs to be dissolved into a solution before it can be introduced into the body, and during the thawing process, due to the obvious change in temperature, the protein may be denatured. If the albumin can avoid the process and phenomenon of freezing with the sail during the freezing process, and does not need to be dissolved during injection, it can be frozen.

1. Human albumin must be stored in the dark at a temperature of no more than 25.

2. Do not freeze, albumin will be denatured and inactive after freezing.

Storage method] There was a storage method before: low temperature storage at 2-8 degrees.

Later, a method was added, which is to store at room temperature, but the expiration date of the two is not the same. One is 5 years and the other is 3 years.

[How to use].Human albumin can be used directly by intravenous infusion. In the case of large infusions, the product must be rewarmed to human body or room temperature before use. The solution should not be used if it is cloudy or precipitate, indicating that the protein in the solution is unstable or the solution has been contaminated.

Once the container has been opened, it must be used immediately. Unused products must be disposed of in accordance with the corresponding requirements.

Albumin is best stored at 2-8 degrees, protected from light. Although it is more expensive, it is still more important to be healthy.

If it cannot be used, albumin will be denatured and inactive after freezing. As a result, its physiological activity disappears, so after degeneration, its original role does not exist.

Human blood albumin.

Storage conditions: 2--8 degrees away from light.

Cryostorage. Exceed this temperature.

Albumin is hydrolyzed and denatured.

In short, don't use it.