What are the benefits of using a Chinese medicine wall breaker?

Improve the bioabsorption and utilization of active ingredients in traditional Chinese medicine Generally, most of the cells in the crushed particles are complete, and the particles are composed of several, dozens or even more cells. The dissolution of the active medicinal components in the cell needs to pass through the cell wall before entering the solvent and then being absorbed by the body. Since a considerable part of the cellular components cannot penetrate the cell wall into the solvent, the bioabsorption of the active ingredients is affected.

After the traditional Chinese medicine cell is broken by ultrafine crushing, the contents of the broken wall cell can directly contact the solvent, and all the active ingredients can directly enter the solvent to be absorbed by the body, and the amount of active ingredients released and the speed of release, the amount of active ingredients absorbed by the body in a unit time will be higher than that of the traditional Chinese medicine powder obtained by the ordinary crushing method, and the types of active ingredients of the drug released are also more. The onset time of the drug will be significantly shortened, and the intensity of the effect on the body will be higher and more comprehensive. After the drug enters the body, it generally goes through the action of beneficial bacteria in the body.

Due to the small size of cell-level wall-breaking micronized Chinese medicine particles, the effect of beneficial microflora is rapid and intense, and the amount and concentration of products through the action of microflora will be significantly increased, which also helps the body to absorb. Because the ultra-fine powder particles have surface effect, volume effect, quantum effect and macroscopic tunnel effect, etc., so that they have greater adsorption of substances, so as to strengthen the adhesion of cell-level micronized Chinese medicine on the intestinal wall, so that the residence time of traditional Chinese medicine particles in the intestine is prolonged, which is conducive to the absorption of drugs. When the drug enters the stomach with cell-level ultrafine crushing, the soluble components dissolve under the action of gastric juice, and the dissolved components begin to be absorbed after entering the small intestine.

Because the drug is ultrafine particles, its insoluble components are also very easy to attach to the small intestinal wall, and the active ingredients adsorbed on the cell wall will be quickly absorbed through the intestinal wall and enter the bloodstream, and these ultrafine particles take a long time to be excreted from the body due to the influence of adhesion, which improves the absorption rate of the drug. In addition, due to the shortening of the time required for the migration of active ingredients from intracellular to extracellular, the absorption rate is significantly accelerated and the absorption amount increases. Taking cell-level wall-breaking ultra-fine grinding of traditional Chinese medicine will make the body absorb more comprehensive drug components, higher absorption intensity, and greater absorption, thereby significantly improving the bioavailability of traditional Chinese medicine.

In the process of cell-level mixing and micro-grinding of compound Chinese medicine, the components can be evenly mixed through high-strength shear force, so that the solid material can achieve the effect of liquid phase mixing and emulsification, the current production process of compound Chinese medicine is generally composed of two processes of crushing and mixing, and the two processes can be combined into one process by using the ultrafine grinder of traditional Chinese medicine, and the fineness of crushing can generally reach 300 mesh, with high work efficiency and good mixing uniformity. Its working principle is to use vibration to make the medium produce vibration impact and medium rotation, so that the powder can get a positive impact and shear force at the same time, and crush at high speed and high energy, which is a kind of high-efficiency and energy-saving crushing equipment.

Improve the quality, hygiene quality and addition scope of veterinary traditional Chinese medicineWhen the cell wall is broken and ultrafine pulverized by the traditional Chinese medicine, the eggs equivalent to the cell scale will also be killed, thereby reducing the pollution and damage of insect pests to Chinese herbal medicines. Because the ultra-fine grinding process is a pure physical process, it will not be mixed with other impurities, so that the processed traditional Chinese medicine has the characteristics of pure natural Chinese veterinary drugs, which ensures the integrity and safety of the raw materials; Due to the ultra-fine treatment, the particle size is very fine, which improves the taste of the product, which can be directly dissolved in the drinking water of animals and can also be used as a feed premix. ConclusionThe ultra-fine grinding technology makes the production of traditional Chinese medicine easy to achieve sterility, pest-free, small packaging, easy to achieve standardization and mechanization, and promotes the modernization and scientific management of traditional Chinese medicine production. Due to the reduction effect of micronized Chinese medicine in use, it can save resources and reduce costs, which provides an effective means for the development of traditional Chinese medicine.

Due to the ease of use of micronized Chinese medicine, it has promoted the promotion of natural medicine and further expanded the influence of traditional Chinese medicine. Ultra-micro Chinese medicine has good quality, strong efficacy, high technology content, and high value-added rate, which can bring good social and economic benefits to enterprises. The application of ultrafine grinding technology in the development of traditional Chinese medicine resources has brought a huge impetus to the improvement of traditional processes and formulas, and the development of new products, and has provided an effective means for the transformation of existing traditional Chinese medicine pharmaceutical processes.

As a new type of resource processing method, ultrafine grinding technology has been widely used in developed countries. At present, China's theoretical research on ultrafine grinding technology has been basically the same as that of developed countries, but there is still a big gap in applied research, especially in product market development. After China's accession to the WTO, the development of traditional Chinese medicine has become a national policy, ultrafine grinding technology is the current international advanced grinding technology, the world's advanced technology will be applied to the field of traditional Chinese medicine, will improve the level of traditional Chinese medicine preparations and Chinese patent medicine to the world and veterinary Chinese medicine products to the international market to contribute.

By adjusting the difference of positive pressure and shear force to adapt to various materials, it can carry out high-viscosity and high-precision solid-solid and solid-liquid mixing of any material. During crushing, the grinding temperature can be controlled by introducing cooling water into the grinding drum sleeve according to requirements. After the compound drug is broken by ultramicrocells, the water and oil in the cells are migrated out, so that the surface of the microparticles presents a semi-wet state, and a stable particle cluster will be formed between the particles, each particle cluster contains the same proportion of traditional Chinese medicine ingredients, and the physical structure of the particle cluster is different with the different combinations and interactions of the hydrophilic and lipophilic balance (HLB) value, ductility, fragmentation, water (oil) content, specific gravity and other components of each component in the component, and this structure will homogenize the active ingredients of the Chinese herbal medicine. The various ingredients are evenly absorbed by the body, thereby enhancing the effect of the drug.

The homogenized oily and volatile components of Chinese medicine can be dispersed and evenly dispersed soon after entering the stomach, and absorbed in the small intestine in sync with other water-soluble components. This is obviously different from the absorption rate and absorption amount of unbroken wall medicinal materials obtained by conventional crushing method. Significantly improve the industrial extraction rate of active ingredients of traditional Chinese medicineIn the extraction of traditional Chinese medicine, the dissolution of the active ingredients needs to go through the processes of infiltration, swelling, osmosis and diffusion.

On the one hand, the use of ultrafine grinding technology reduces the dissolution resistance of the active ingredient, and on the other hand, the fine material has strong surface adsorption, affinity, dispersion and solubility, thereby improving the dissolution speed and dissolution rate of the active ingredient. Experiments have proved that cell-level ultrafine grinding technology can significantly improve the extraction rate of active ingredients in traditional Chinese medicine, especially for macromolecular components.

If you buy a wall breaker at home, you can't do it, which brings great convenience to daily life and can be used to make food. What are the functions of the household wall breaker? PChouse will take you to find out.

1. The wall breaker is an electrical appliance with many functions, such as: stirring, wall breaking, heating food, etc., so the wall breaker can not only squeeze juice and make hot soybean milk, but also make ice cream, jam, milkshake, rice cereal, vegetable juice, smoothie, etc., in addition, it can also be used to make fish soup, porridge, medicinal soup and so on.

2. The power of the wall breaker is generally relatively large, and the speed is also very fast, so it is often used for grinding, stirring, grinding meat, etc., that is to say, as long as you buy a wall breaker, it is equivalent to buying multiple machines, which is a very cost-effective thing for the majority of users.

3. It can be used to make ordinary squeezing brother juice, soybean milk, stirring and breaking walls, and even heating food, which is also difficult to do for ordinary juicers, and even can make ice cream, jam, milkshake, smoothie, etc., and can also be used to grind meat and grind dry powder, because the power is very large, the speed is fast, the blade is sharp, and the food can be crushed quickly, which is not something that ordinary machines can do.

Pollen has not been developed and utilized in China for a long time, and many people do not have a comprehensive understanding of pollen, such as thinking that "pollen that cannot break the wall will not be absorbed".

Pollen is surrounded by two layers of pollen walls, and the outer wall is harder, so some people think that the wall must be broken when eating. But pollen has many germination pores, and many nutrients can be released from the germination pores. Years of scientific research and clinical observation have shown that pollen products taken internally do not need to break the wall.

Both large and small animal experiments and clinical observations on humans have proved that the nutrients of pollen can generally be digested and absorbed after the action of digestive enzymes in the oral cavity, stomach and intestines. Stool examination revealed that there were almost no remaining nutrients in the pollen residue of the stool, and no intact pollen grains could be found.

There is basically no difference in the digestion and absorption rate of wall-breaking pollen and non-wall-breaking pollen.

After the pollen is broken, various enzymes and other bioactive substances that are beneficial to the human body are more easily denatured. And if the pollen after the wall is not well packaged and stored, it is easy to mildew. If you use the raw materials of pollen cosmetics and other external skin care products, in order to facilitate the absorption of nutrients such as amino acids, vitamins C and E, it is best to go through the wall-breaking process to extract them to make the skin care effect better.

1. The traditional Chinese medicine cell wall breaker is the use of high-frequency vibration of the cylinder, the steel ball or steel rod medium in the cylinder relies on the inertial force to impact the material, and the acceleration when the medium rushes the material can reach 10g-15g, so it has the advantages of compact structure, small size, light weight, low energy consumption, high output, concentrated grinding particle size, simplified process, simple operation, convenient maintenance, etc., and can be widely used in precious Chinese herbal medicine, ceramics, graphite and other industries to make powder. The characteristics of the traditional Chinese medicine cell wall breaker are that the chassis support cylinder elastically holds up the body through the support spring, and keeps the flexible connection distance between the drive motor and the vibrating body unchanged.

2. The grinding drum is the working body of the mill vibrating, which is used to contain the grinding medium and abrasives. The exciter is used to convert the rotational distance of the motor into the periodic vibration of the mill. The liner is attached to the inner wall of the grinding drum to protect the main grinding drum during the grinding process.

The working principle of the traditional Chinese medicine cell wall breaker is that a certain amount of grinding medium is filled in the grinding drum (grinding chamber), such as a ball, rod or column of hard material, and the grinding drum produces a circular vibration in a clockwise and counterclockwise square as shown in Figure 1 under the action of the external excitation force. The strong vibration of the grinding drum makes the medium in the grinding drum produce throwing motion, and under the action of this throwing motion, each medium produces a rotating motion in the same direction as the circular vibration, and at the same time, the medium group also produces a low-frequency revolution motion that is 3-5 cycles in the opposite direction of the circular vibration. As a result, the media sometimes spread apart and sometimes collide with each other, resulting in the positive impact force p and lateral shear force l shown on the material.

The material is finely ground and broken under the impact, compression and shear of P and L forces.

3. Changing the physical state of drugs by traditional Chinese medicine powder machine is a method worth actively exploring to improve the efficacy of high regret drugs and develop new drugs. The amount and speed of the effective ingredients of traditional Chinese medicine are released by the micropowder technology, and the amount of effective ingredients absorbed in a unit time will be higher than that of the traditional Chinese medicine powder obtained by the ordinary crushing method, and the types of active ingredients released by the drug will be more complete than that of the ordinary crushing method, and the effective time of the drug will be significantly shortened and the effect will be more comprehensive.

It must be affirmed that nano Chinese medicine is of great significance for the use of high and new technology to improve the quality and level of traditional Chinese medicine, however, nano Chinese medicine is far from perfect, first of all, the composition of traditional Chinese medicine is very complex, and the mechanism is unknown, it is nano treatment, through the modification of nanoparticles, it is possible to correct the original defects of some traditional Chinese medicine, and the efficacy is enhanced, but it may also be counterproductive. If nano treatment is carried out, it is possible to multiply the A effect of traditional Chinese medicine, and it is also possible to significantly weaken the B effect, and it is also possible to produce the C effect and D effect that were not originally available. In terms of toxicity and side reactions, similar changes may occur, and the non-circular certainty of the active ingredients and pharmacodynamics of traditional Chinese medicine after nano-localization will leave hidden dangers for the stability and controllability of drug quality.

Secondly, the scope of nano Chinese medicine should be limited, and if it is limited to certain mineral drugs containing low molecular weights, inorganic molecules or poorly soluble molecules, it has important practical value. However, if the scope of nanopreform is extended to include even Chinese herbal decoction pieces, care should be taken not to damage the active ingredients of the drug in order to obtain nanoparticles. Each Chinese herbal decoction piece is like a warehouse containing many compounds, and people still do not know the active and inactive ingredients clearly, and the hasty nanoprocessing of them may outweigh the losses. At the same time, the current preparation cost of nanoparticles is too high, and the traditional Chinese medicine, which originally won with high quality and low price, will lose its advantage after nanoprocessing.

Therefore, even if nano Chinese medicine is technically mature, it may be difficult to promote due to the best factors. The last problem is that due to the ultra-fine particle size, nano Chinese medicine may affect the stability of the drug and increase the difficulty of quality and storage.

This machine can effectively crush any fibrous, high-toughness, high-hardness or certain moisture content materials, especially suitable for the crushing requirements of traditional Chinese medicine cells to improve the bioavailability of drugs and materials that cannot reach the required fineness by conventional methods. In addition to being used in biopharmaceutical, natural (health) food and cosmetics, it is also widely used in building materials (preparation of ultra-fine water slag, fly ash, etc.), chemical industry, metallurgy, environmental protection (garbage powder bricks, etc.), electronics (paddle materials, graphite milk, etc.) and other industries related to powder applications.

1. Fineness: 20-3000 mesh, no grading process (according to different materials extra-coarse acacia animal), the wall breaking rate is as high as 98 or more, so that the rock is good at absorbing and expanding the curative effect, saving medicinal materials.

2. Temperature: The medicinal materials are broken and crushed in an adjustable environment from minus 30 degrees to minus 50 degrees (freshness, and the living material does not change). [The machine needs to be equipped with a special cooling device].

3. Sealed: fully enclosed operation, no pollution, no volatile, no loss, in line with GMP requirements.

4. Mixing: with each super mixing force, it can reach plus or minus 1/1000 uniformity in a short time.

5. Take: Compound micro-bird mu powder can be directly taken (without decoction), or directly used as a raw material for any dosage form (without extraction).

In the future promotion and practicality, it will bring great convenience and benefits to patients, hospitals, preparations and many other aspects. At present, in the crushing process of traditional Chinese medicine pharmaceuticals (preparations) in China, it has irreplaceable technological advancement and leading position.