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Parkinson's disease is a neurodegenerative disease that is common in middle-aged and elderly people, so the common age of onset of Parkinson's disease is after the age of 60, and it is relatively rare before the age of 40, with an average age of onset of about 55 years old. In China, the prevalence of 65-year-old people is higher, and with the increase of age, the prevalence will gradually increase, and the prevalence is slightly higher in men than in women. The pathology and pathogenesis of Parkinson's disease are not fully understood, but Parkinson's disease is closely related to some related factors, such as genetic factors, environmental factors, and nervous system aging.
Especially the aging of the nervous system, for example, after the aging of the nervous system of the elderly, the dopaminergic neurons in the substantia nigra begin to degenerate, and the dopaminergic neurons gradually decrease, which is one of the precipitating factors of Parkinson's disease.
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Kinson disease can occur in all ages, from adolescence to old age, and most often begin at the age of 50 to 65.
Parkinson's disease is a neurodegenerative disease that is common in middle-aged and elderly people, with an average age of onset of about 55 years old, more common after the age of 60, relatively rare before the age of 40, in people over 65 years old, the prevalence rate is increased with age, the prevalence rate is 3% 5% over 70 years old, slightly more in men than in women. With the aging of the population, the number of patients with Parkinson's disease is also increasing, coupled with environmental factors, genetic factors, age factors and long-term mental stress
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Parkinson's disease mainly occurs in middle-aged and elderly people, and it is relatively rare before the age of 40, because the aging of the nervous system is related to the onset of Parkinson's disease. Some data show that after the age of 30, with the increase of age, the substantia nigra dopaminergic neurons begin to degenerate, and the dopaminergic neurons gradually decrease, despite this, but the degree is not enough to cause the onset of the disease, and there are only a few patients in the elderly population, so the aging of the nervous system is only a precipitating factor for Parkinson's disease. At present, it is believed that Parkinson's disease is not caused by a single factor, but is caused by the interaction of multiple factors.
Therefore, Parkinson's disease does not always occur in the elderly, but only a small number do.
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Parkinson's is very common in older adults. Parkinson's is also known as paralytic tremor. Parkinson's is considered to be genetic, or because of recurrent cerebrovascular disease. Prolonged exposure to pesticides or heavy metal poisoning can also lead to the occurrence of panison.
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Parkinson's disease is one of the most common types of neurodegenerative diseases in middle-aged and older people, mainly due to problems with the substantia nigra in the midbrain. The decrease in dopaminergic neurons in the substantia nigra results in a group of syndromes caused by a decrease in dopamine in the brain, which is divided into motor and non-motor symptoms. Motor symptoms most commonly manifest as tremor, hypotonia, bradykinesia, and postural disturbances, and non-motor symptoms are also numerous, with the main symptoms being depression, anxiety, insomnia, unexplained sensory disturbances and pain, and decreased cognitive function and intelligence.
For Parkinson's, it is basically impossible to increase the concentration of dopamine in the brain or increase the use rate of dopamine, and improve the symptoms of patients. Drugs** only improve symptoms and slow progression, and eventually the patient will definitely progress to the point of inactivity and paralysis.
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Parkinson's disease, also known as tremor paralysis, is the most common degenerative disease of the central nervous system in middle-aged and elderly people, but a small number of patients with Parkinson's disease suffer from this disease before the age of 40, and some patients are even diagnosed in their 20s
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Parkinson's is a common disease in middle-aged and elderly people, Parkinson's mainly occurs in middle-aged and elderly people, and the onset before the age of 40 is rare, suggesting that aging is related to the onset of the disease.
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Parkinson's disease is a common progressive neurodegenerative disease in clinical practice, with a prevalence of about 1% in people over 55 years old, and there are more than 2 million PD patients in China.
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The following people are susceptible to Parkinson's:
1. The elderly, especially those over 60 years old, have a relatively high incidence of Pa Leak Weiyou Jinsen;
2. People with a family history of Parkinson's are suspicious and prone to Parkinson's;
3. People who have been exposed to toxic and harmful substances for a long time, such as workers in pesticides and chemical plants, are prone to Parkinson's;
4. People who take antidepressant, anti-anxiety and antipsychotic drugs for a long time are prone to Parkinson's.
These people are the people with a high incidence of Parkinson's, especially for people who are exposed to toxic and harmful substances, and better protective measures should be taken to avoid toxic and harmful substances, damage to brain neuronal cells, and cause Parkinson's disease.
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What are the symptoms of Parkinson's?
1.Tremor. When there is a purely involuntary shaking or tremor of the arms or fingers in a quiet state, it is necessary to be suspicious that Parkinson's is responsible, and the tremor is usually aggravated by emotional stress or excitement.
Some people experience tremors all over the body, but the tremors in the hands are the most noticeable and direct.
2.Muscle stiffness.
Due to the increased muscle tension, the flexibility of the patient's trunk and limbs will decrease, often resulting in stiffness or excessive tension of the Chensong muscles, generally one side of the limb begins to stiffen the joints and muscle stiffness, as if cramps are uncomfortable, and the completion of simple sitting, unbuttoning or other actions is not high.
3.Sluggishness.
Simple actions such as unbuttoning and tying shoelaces, which used to be done quickly, now take longer to complete, i.e., they become much slower or slower than before, or even more laborious, and sometimes it is difficult to lift your feet and even take steps when you have to start again. When the patient is asked to write the font, they will find that it becomes difficult to write and the font becomes smaller and smaller, which is called "lowercase syndrome".
4.Abnormal gait.
Abnormal stride can be said to be a more common and iconic indication of Parkinson's disease, patients have an unstable center of gravity during walking, so they are particularly prone to fall or sudden stagnation of their feet, sometimes the pace will become smaller or rush forward in broken steps, and because they cannot stop in time, they will show a panicked step posture.
5.Abnormal sense of smell.
Most people with Parkinson's disease have a loss of smell or complete loss of smell after the disease, making it difficult to recognize the smell or taste of food. In addition, damage to the dorsal nucleus of the vagus nerve interferes with autonomic nerve function, slows gastrointestinal motility and causes symptoms of intractable constipation.
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Relatively speaking, there are a lot of middle-aged and elderly people.
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Parkinson's disease is a common disease in old age, also known as parkinsonism, which is a common degenerative disease of the nervous system in middle-aged and elderly people.
First, the proportion of Parkinson's disease in the elderly is still relatively large. Among the elderly over 65 years old, about 1% of the population has Parkinson's disease, which is a relatively common disease of the nervous system degeneration in middle-aged and elderly people.
2. At present, the pathogenesis is not very clear, and the main considerations are related to genetic factors, physical and chemical factors, nervous system lesions, environmental and other factors. The common clinical symptoms are mainly resting tremor, mask face, stiff limb muscles, and slow movements, which may lead to balance impairment.
3. At present, there is no particularly effective way to delay the progression of Parkinson's disease, mainly through drugs. If necessary, surgery can also be used to reduce symptoms**.
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Yes, but there are also young people who get sick.
There are also some patients between the ages of 20 and 30, but the proportion is relatively small.
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Parkinson's is relatively new to many people, but the symptom of "Alzheimer's disease" is familiar. Because of the limited understanding of Parkinson's disease, many people think of Parkinson's disease as Alzheimer's disease. In fact, some of the symptoms of Parkinson's disease are indeed very similar to Alzheimer's disease, but is Alzheimer's disease Parkinson's disease?
Because people with Parkinson's disease will have dementia and other manifestations in the later stages, many people mistakenly confuse it with Alzheimer's disease. In fact, these are two completely different diseases. Parkinson's disease and Alzheimer's disease Although the problem is in the "mind", Parkinson's disease is caused by the transmitter dopamine nerve cell lesion in the "substantia nigra" of the brain, while Alzheimer's disease is caused by the temporal hippocampal lesion of the brain, so Parkinson's disease and Alzheimer's disease are different.
In addition, the problem of Alzheimer's disease often lies in the deficits in intelligence, orientation, calculation, and memory. "Where am I from?" "Where do I live?" Parkinson's patients generally only show slowness in movement and speech.
Experts point out that Parkinson's disease is becoming more and more common in the elderly population, and many people often have such misunderstandings, and even regard it as a normal phenomenon in the aging process. If you can't correctly distinguish the difference between Parkinson's and Alzheimer's disease, it is easy to misdiagnose, so it is very important to do a good job of Parkinson's self-examination! Because Parkinson's disease patients will have some very typical symptoms in the early stage of the disease, the family members of the elderly can use the following test methods to determine whether the elderly have been quietly invaded by the disease.
Tremor is usually the earliest manifestation of Parkinson's disease, usually with unilateral finger rubbing-like movements, followed by involuntary rhythmic tremors of the ipsilateral lower and contralateral limbs at rest, and in the early stages, symptoms may be reduced or stopped when changing positions or movements. In real life, if the elderly often have similar symptoms as above, family members need to be vigilant, and timely grasp the best timing is the key.
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Parkinson's diagnosis and treatment is to help us solve these problems with TCM recuperation. If you need to control it, then use Western medicine, otherwise you will use Chinese medicine to help you recover your body and fight the disease.
Traditional Chinese medicine to Parkinson's: First of all, we often say that "Parkinson's is old age and body weakness", so what is body deficiency. Traditional Chinese medicine refers to the weakness of the constitution as body deficiency, and the weakness of chronic diseases as deficiency syndrome, and divides weakness into four types: qi deficiency, blood deficiency, yin deficiency, and yang deficiency.
The five organs all have the symptoms of yin and yang deficiency and reality, and Parkinson's is mainly what Chinese medicine calls "blood deficiency and wind.""Abbreviated as "Wind Certificate".
Jishi Pingfeng Soup**": Quench the liver wind and relieve spasms, nourish the kidneys and replenish the brain and marrow, activate the meridians to make the meridians smooth, regulate the spleen so that nutrition can reach the whole body and relieve spasms. Parkinson's is different for each person, and there will be additions and subtractions according to each person's different conditions.
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Yes. Parkinson's disease is a common neurodegenerative disease, which is more common in the elderly, with an average age of onset of about 60 years old, and less common in young people under the age of 40.
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Yes, Parkinson's is basically more common in middle-aged and elderly people.
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People say that the elderly are the most common group of people with Parkinson's, why is this so? What are the reasons to prove this statement, and why are the elderly more likely to suffer from Parkinson's disease? Briefly introduce the following, why are the elderly a high-risk group of Parkinson's?
What are the tests that can be used to draw conclusions?
First. Routine laboratory tests are generally within the normal range, and some individuals may have hyperlipidemia, diabetes, abnormal electrocardiogram and other changes.
Second. Cerebrospinal fluid (CSF) examination may detect a decrease in dopamine levels and a decrease in the concentration of its metabolite homovanillic acid. The content of serotonin metabolites and hydroxyindole acetic acid is reduced; decreased dopamine hydroxylase; The cerebrospinal fluid (CSF) has significantly decreased somatostatin and the level of aminobutyric acid has decreased.
Third. Molecular biology assays Biochemical testing uses high-performance liquid chromatography (HPLC) to detect decreased levels of HVA in cerebrospinal fluid and urine. Genetic testing uses DNA blotting technology (Southern Blot), PCR, DNA sequence analysis, etc., and gene mutations may be found in a small number of patients with familial PD.
Fourth. Brain CT and MRI examinations are generally uncharacteristic, and elderly patients may have different degrees of cerebral atrophy and ventricular enlargement, and some patients have lacunar infarction foci and individual basal ganglia calcification.
Fifth. Functional imaging tests are performed using PET or SPECT with specific radionuclides. For example, 6-(18fluoro)-levodopa (6-FD) studies the metabolism of dopamine, information about the density and affinity of dopamine receptors can be obtained, and it is found that the dopamine metabolism function in the brain of Parkinson's patients is significantly reduced, and the absorption index of the striatum can be found to be less than normal before the onset of clinical symptoms.
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Everyone knows that Parkinson's is a common disease among middle-aged and elderly people, and I often hear people ask me why the elderly are prone to Parkinson's. What causes this? Here I will briefly introduce to you why the elderly are prone to Parkinson's disease, I hope it will be helpful to you.
1. Familial hereditary: In long-term practice, medical scientists have found that Parkinson's disease seems to have a tendency to gather in families, and the incidence of Parkinson's disease patients in their relatives is higher than that of the normal population.
2. Parkinson's patients often have an acute history of poisoning, and gradually show signs of diffuse brain damage, including general stiffness and mild tremor.
3. Multiple lacunar cerebral infarctions occur in the brainstem and basal ganglia caused by cerebral arteriosclerosis, which affects the substantia nigra dopamine-striatum pathway.
4. Environmental factors: Epidemiological investigations have found that there are regional differences in the prevalence of Parkinson's disease, so people suspect that there may be some toxic substances in the environment that damage the neurons of the brain.
5. Aging: Parkinson's disease mainly occurs in middle-aged and elderly people, and the onset before the age of 40 is rare, indicating that aging is related to the onset of the disease. Studies have found that since the age of 30, the activity of dopaminergic neurons, tyrosine oxidase, and dopa decarboxylase in the substantia nigra, and the level of dopamine transmitters in the striatum gradually decrease with age.
However, only a small number of elderly people suffer from this disease, indicating that physiological dopaminergic neuronal metamorphosis is not enough to cause the disease, and aging is only a precipitating factor for the onset of this disease.
6. Infection: This syndrome can appear after encephalitis and head injury, such as A encephalitis, which has an incubation period of several years after healing, and slowly appears severe and long-lasting PD syndrome.
7. Drugs: clinical symptoms or pathological changes caused by taking antipsychotic drugs and tricyclic antidepressant drug poisoning, suspected to produce Parkinson's similar symptoms, and some can completely disappear after stopping the drug.
8. Poisoning: such as carbon monoxide, manganese, mercury, cyanide poisoning, gas poisoning is more common in the north. Patients often have an acute history of poisoning, followed by signs of diffuse brain damage, including generalized rigidity and mild tremor.
Be sure to pay attention to rest, be sure to eat a light diet, don't eat high-fat food, be sure to strengthen exercise, drink plenty of water, and follow the doctor's advice to use drugs reasonably.
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