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There are many types of progressive muscular dystrophy, and the clinical manifestations of each type are different, the genetic manifestations are also different, and the types of diseases and complications are also different. It is more common to have contracture of the Achilles tendon with the aggravation of the disease, drooping of the feet, difficulty in walking on flat ground, easy to fall, injury, and more serious can lead to fractures. Some types are accompanied by myocardial damage, arrhythmia, cardiomegaly, valvular insufficiency, and heart failure in more severe patients.
In the later stages, there is inability to walk, muscle atrophy due to wheelchair use, or joint stiffness. Some patients with advanced disease will be concurrent with lung infection when they are bedridden, and eventually they will have respiratory muscle weakness and respiratory failure. In addition, there are patients who will have mental retardation, hip dislocation, etc.
Less common complications are due to acute gastric distension or more severe wasting disease.
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1. Achilles tendon contracture.
Achilles tendon contracture is a common complication of progressive muscular dystrophy, which can lead to drooping feet, difficulty walking on flat ground, and if the symptoms are too severe, it can lead to easy falls and injuries.
2. Myocardial damage.
As the condition of patients with progressive muscular dystrophy progresses, it can also affect the health of the heart, leading to discomfort such as irregular heartbeat, heart enlargement, and heart valve insufficiency, and possibly heart function.
3. Mental retardation and hip dislocation.
If the symptoms of progressive muscular dystrophy are too severe and not effective**, it will affect the patient's intelligence, eventually develop mental retardation, and in a few cases, the hip joint will also be dislocated.
It can be seen that the harm of progressive muscular dystrophy is serious, once the onset of the disease requires long-term intermittent**, patients can choose glucocorticoids according to the doctor's instructions, and use drugs according to the regulations to stabilize the condition and reduce the discomfort of gait abnormalities and muscle atrophy. If necessary, it is necessary to carry out corresponding ****, such as standing inclined board, foot orthopedic brace, etc., which can play an auxiliary role and then improve the patient's condition.
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[Clinical symptoms].
Progressive worsening of skeletal muscle atrophy and weakness of varying degrees and distributions.
Hazards] affect motor function, and in severe cases, it can lead to paralysis, and can also affect the heart, causing cardiac dysfunction.
Complications] limb contractures, lung infections, pressure ulcers, heart damage, etc.
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Symptoms of muscular dystrophy: infantile patients walk with a slow gait, easy to fall, delayed walking age, swaying pelvis from side to side when walking, heel can not touch the ground, Achilles tendon contracture, lordosis, back of the head, shoulder muscle atrophy, weakness, ** wrinkles, shoulder muscle atrophy, pterygoid shoulder deformity, pediatric patients have spine and limb joint deformities, later limb contractures, and complete loss of motor function. It is usually accompanied by lung infection, heart damage accompanied by symptoms such as palpitation, ulcers and bedsores, and a significant decrease in IQ in children.
It is still unclear that there are no specific medications.
Muscular dystrophy is a hereditary muscle degenerative disease, and there is no specific way, only symptomatic and supportive. It can increase the patient's nutrition, normal activities, physical ** and orthopedics, and can prevent and improve the deformation of the spine and the contracture of the joints. Because it is a lesion of the patient's muscles itself, strenuous exercise is not encouraged, and appropriate activities can be carried out to avoid long-term bed rest.
ATP, inosine, and vitamin E can be given orally or intravenously to provide energy support.
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Muscular dystrophy is divided into stages. Before the age of one, toddlers are largely unable to walk normally, are anorexic, do not respond to things around them, or walk in circles. In childhood, it may be more obvious, often walking and swaying, like a duck, the mobility ability is obviously not as good as other children of the same age, holding a pen unsteadily, unable to write, etc.
In the later stage, as the symptoms cannot be relieved by timely intervention, the symptoms in the early stage will continue to worsen and affect the whole body. Patients in the advanced stage generally have generalized muscle weakness, inability to take care of themselves, mental decline, and severely affected vision, which is very difficult. However, some people also said that they had drunk Shengmyelin Rejuvenation Soup in the later stage to greatly alleviate the severe symptoms of muscular dystrophy.
Spicy foods are contraindicated in patients with muscular dystrophy, and patients with advanced muscular dystrophy should pay attention to ensuring lung function.
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The causes of muscular dystrophy include vascular origin, neurogenic disease, muscle fiber regeneration disorder, muscle cell membrane dysfunction and other theories. The disease** is a genetic abnormality that can be carried out in different ways in different types, but it is never clear how genetic factors ultimately cause muscle degeneration.
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Hello, glad to help you with your answers. Muscular dystrophy is caused by heredity or mutation of one's own genes, and is more common in children and adolescents, which brings a lot of inconvenience to the health and growth of patients, so special attention should be paid to the care of patients in their daily lives.
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Malignant muscular dystrophy: pseudohypertrophic muscular dystrophy is common, with onset at the age of 3-4 and paralysis at the age of 8-9, with an average survival time of 16 years and an incidence of 1 5000In recent years, it has been internationally recognized that the disease can be treated, and the use of drugs and drugs can delay walking time and prolong the life of patients.
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Muscular dystrophy is a disease that is difficult to treat, but it is not incurable. Muscular dystrophy can only be done earlier if it is detected early, and here we can help you get better.
Muscular dystrophy is mainly a muscle degenerative disease caused by genetic factors, and in addition to genetic factors, the patient's own genetic mutations can also lead to the occurrence of the disease. Progressive muscle atrophy and weakness are the main clinical manifestations, and a large number of patients are caused by gene mutations.
Muscular dystrophy is not a single disease, and some are inherited in an autosomal recessive manner. It can occur in both sexes. Most of them start in adolescents, but some do it later.
The first symptom is weakness and atrophy of the pelvic girdle muscles. The disease progresses slowly, gradually involving the shoulder girdle, and typical symptoms such as difficulty lifting the arms and winged shoulders appear.
In addition, some patients present with ptosis and progressive extraocular muscle palsy. Some patients experience muscle weakness and atrophy of the head, face, throat, neck, or other limbs. A small number of patients may have damage to the spinal cord, cerebellum, and retina, mental retardation, and abnormally high cerebrospinal fluid proteins.
Duomu Health reminds you that muscular dystrophy will cause symmetrical weakness and atrophy of the muscles of the limbs, walking slowly and falling and not easy to get up, difficulty and effort to go up and down stairs, and the heel cannot touch the ground The calf muscles are cold, hard and thick. Therefore, it is important to find a professional hospital for diagnosis and treatment as early as possible.
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Hello, glad to answer for you.
Constant muscular nutrition can lead to complications in patients, such as pneumonia, otitis media, thrush, anemia, hepatosplenomegaly, hypoglycemia, severe malnutrition, etc., which may endanger the lives of patients.
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Muscular dystrophy can lead to complications in patients, such as pneumonia, otitis media, thrush, anemia, hepatosplenomegaly, hypoglycemia, severe malnutrition, etc., severe may endanger the patient's life, and the patient needs to actively delay the development of the disease and improve the patient's quality of life.
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Muscular dystrophy is a group of inherited muscle degenerative diseases, mainly caused by genetic abnormalities, and patients often have genetic defects and are familial clusters. Some patients have no history of the disease and are caused by genetic mutations. 1. Gene defectsGene defects can lead to protein abnormalities that maintain the structural and functional stability of skeletal muscle cells, thereby affecting the normal movement of associated muscles.
For example, patients with DMD or BMD malnutrition are affected by decreased dystrophin synthesis. Dystrophin acts as a scaffold to protect muscle cells from damage by protecting the muscle membranes from the forces generated by contraction. 2. Familial cluster muscular dystrophy can cause multiple people in the family to develop the disease, or someone may develop it first.
3. Gene mutationsSome patients do not have a history of muscular dystrophy in their families, and their own disease may be due to new gene mutations. This is rare.
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1. Pseudohypertrophy: In early childhood, patients usually show that the walking age is delayed, walking slowly, easy to fall, and it is not easy to get up after falling, and most of them are accompanied by calf muscle hypertrophy. As the disease progresses, most children lose the ability to walk around the age of 10 and are confined to wheelchairs or sit on their laurels, resulting in spinal and limb deformities.
In the late stage of Iwazakura, contractures of the limbs may occur, or even complete inability to move. Patients with this clinical classification may have varying degrees of IQ decline.
2. Facicoscapulohumeral type: because the facial and scapular girdle muscles are the first to be affected, there may be few facial expressions, weakness of eyelid closure or exposure of the sclera, and difficulty in cheek bulging. With the development of the disease, the trunk and pelvic girdle muscles can be gradually affected, and manifestations such as gastrocnemius hypertrophy, retinopathy, and hearing impairment may occur.
3. Limb girdle type: The first symptoms of this clinical type are mostly pelvic girdle muscle atrophy, lumbar lordosis, duck step, difficulty in going upstairs, etc., with the progress of the disease, it can be due to shoulder girdle muscle atrophy and difficulty in raising arms, combing hair and other manifestations of rough wisdom.
4. Eyepharyngeal type: The first symptoms of this clinical type are often symmetrical ptosis and ocular motility disorders, and mild facial muscles, eye muscle weakness and atrophy, slurred speech, dysphagia and other manifestations may gradually appear.
In addition to the above four clinical classifications, there are many clinical classifications of progressive muscular dystrophy, and the symptoms that occur vary according to different classifications, which need to be analyzed according to the specific classification.
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If the genes of a certain muscle are changed, it will produce degeneration and necrosis, resulting in muscle atrophy and congenital muscular dystrophy. Genetic lesions occur in the eyes and pharynx, which is oculopharyngeal congenital muscular dystrophy, and lesions that occur in the face, shoulders, and humerus are faciocapulohumeral congenital muscular dystrophy. The symptoms of different ** are also different, so it is correct to check in time if there is an abnormality.
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Traditional Chinese medicine believes that the kidney is the innate foundation, the main essence is stored, and the bone is the marrow. Muscular dystrophy is a genetic disease, and it is also a syndrome of impotence in traditional Chinese medicine, which is most closely related to the kidneys.
The symptoms of muscular dystrophy are as follows:
First, when young children suffer from muscular dystrophy, the main symptom is that they walk slowly, and the walking age is delayed, and they are prone to falling, and it is difficult for them to get up after falling. >>>More
The focus is on hereditary diseases. According to the genetic mode, pseudohypertrophic muscular dystrophy, Becker guanidine dystrophy, and Emery-Drcifuss muscular dystrophy were X-linked recessive inheritance, while facioscapulohumeral muscular dystrophy and myotonic muscular dystrophy were autosomal dominant inheritance. Limb-girdle muscular dystrophy is inherited in an autosomal recessive manner.
1. Symmetrical weakness and atrophy of limb muscles, walking slowly and falling is not easy to get up, it is difficult to go up and down stairs, and the heel cannot touch the ground. Walks in a typical duck stride. >>>More
In the later stage, it will seriously endanger life in time**.
Malnourished patients should be supplemented with meat and vegetarian supplements.