How can gout be detected early? How should gout be detected in the early stages?

The early manifestations of gout patients are first of all the asymptomatic period, when the patient only finds that uric acid is significantly elevated during physical examination or occasional blood examination, which is called the asymptomatic period; Patients in the asymptomatic phase develop gout, which takes a certain amount of time and is related to genetics and uric acid levels. If the patient's uric acid level is significantly increased, the rate of uric acid crystallization will be very fast, so gout will occur when the crystallization reaches a certain volume.

In addition, the early manifestations of gout are symptoms of joint discomfort, such as awkward joints, or a feeling like a broken foot, and sometimes an acute onset of pain. Therefore, the early manifestations of gout need to pay attention to the laboratory value of uric acid, if the uric acid is very high, it needs to be actively treated to delay the occurrence of gout.

Gout symptoms can cause the phenomenon of elevated uric acid, this phenomenon is usually caused by long-term use of high purine content and long-term drinking, and some are caused by abnormal uric acid metabolism.

For gout, early detection is more conducive to the disease**. The main way to detect early gout is to measure blood uric acid, especially in high-risk groups of gout, who should visit the hospital regularly to check their blood uric acid levels. High-risk groups for gout include obese middle-aged men, middle-aged and elderly people over 60 years old, and people with cerebrovascular diseases, arteriosclerosis and hypertension.

Gout is a common disease in middle-aged and elderly people, and the prevalence of gout is greater in men than in women. Once you have gout, you have to endure the pain caused by the disease for a long time, which has a significant impact on the patient's quality of life. For gout, if it can be detected at an early stage, it can help reduce the damage to the human body and prevent the occurrence of sequelae.

So how to detect gout early?

Measuring serum uric acid concentration is the primary way to detect gout in the early stage, and it has a major role in the early stage of gout. If Tuchun is a high-risk group for gout, it is more important to actively go to a large hospital to carry out serum uric acid testing, rather than seeking medical treatment after the onset of gout.

The high-risk groups of gout include middle-aged and elderly people over 60 years old, middle-aged men with obesity, people with a family history of gout, people who like to drink alcohol and eat meat, and people with cerebrovascular disease, diabetes, myocardial infarction, myocardial infarction, rheumatism and high blood pressure.

1. General healing.

If it is in the early stage of gout, there is generally no prominent disease, and the main treatment at this time is general treatment. Usually pay special attention to the control of diet, drink more water, and drink more than 2000ml of water per day, which helps to promote the excretion of blood uric acid. At the same time, it is necessary to stop smoking and drinking, prevent the intake of foods high in purines, and prevent taking medicines that can cause gout.

During the sudden onset of gout, bed rest should be taken to prevent walking. Hormone drugs, colchicine and other drugs can be used to improve the disease, and mutual medication can be used when the condition worsens. It can also be used in conjunction with the application of traditional Chinese medicine prescriptions with analgesic effects, which can help reduce the adverse reactions of drugs.

2. Medication**.

After the acute symptoms of gout, urate-lowering drugs should be selected to control the blood uric acid level within the normal range to prevent the onset of gout. For those who have already developed tophi, if it seriously affects daily life or compresses the surrounding structures, surgery should be selected. In the process of treatment, special attention should be paid to the maintenance of diet and life attitude, and the rest should be controlled well, and more water should be drunk to prevent sequelae.

Gout, like other medical diseases, is a chronic disease that requires life, and there is no way to pretend to be simple. Even early gout can't be helped. Trousers need to drink 2000 to 3000 ml of water every day to promote uric acid excretion.

Avoid foods high in purines, such as meat, seafood, legumes, etc. Quit smoking, stop drinking, and avoid getting cold and exertion.

The simplest and most effective way to detect gout at an early stage is to measure the blood uric acid concentration in the Lingqing. A large-scale blood uric acid survey can detect uric acidemia in time for the early detection and prevention of gout.

First of all, for people with hyperuria, it is necessary to pay more attention to it, and eat less alcohol and a large amount of food at ordinary times. In particular, if you have a low-grade fever and joint pain with pickpocketing, tests may be needed.

Go to the hospital regularly for physical examinations, pay more attention to the changes in your body, and achieve early detection and early ** to avoid the severity of the disease.

Analysis: Hello, don't be nervous, pay attention to your diet, low-purine foods can be controlled. The most important thing for gout is low-purine food, mild cases can be controlled by paying attention to diet, even if it is serious, you need to pay attention to diet, this is the basis of the drug, otherwise, the effect is not good.

Suggestions: Diet is the first important, you should first stop drinking, especially beer, and avoid eating a diet containing high purines. Animal offal, bone marrow, and seafood are the most abundant in purines; Fish and shrimp, meat, peas, spinach, etc. also contain certain purines; Fruits, vegetables, milk, eggs, etc. do not contain purines.

It is advisable to drink plenty of water to facilitate the excretion of blood uric acid from the kidneys. Usually you will be able to get better and control your symptoms.

Gout is a kind of rheumatism immune disease, gout is a kind of anti-action inflammatory disease caused by excessive uric acid production and uric acid excretion disorders in the body, resulting in the deposition of urate crystals in other tissues such as joints, synovium, bursa, cartilage and auricle.

Gout can occur in different joints, such as the big knuckle joint, the back of the foot, the heel, the ankle joint, the knee joint, the wrist joint and the elbow joint, etc., the patient presents with progressive pain, the pain at night is more severe, tearing, cutting or biting pain, unbearable, there can be redness, swelling, heat and pain around the joint, which will cause functional limitations.

In addition, there may be systemic symptoms such as fever, chills, and headache. There are no specific symptoms during intermittent episodes, but some patients can develop chronic tophi lesions, in which large amounts of uric acid crystals are deposited in the subcutaneous area, joints, synovium, cartilage, bone and periarticular soft tissues due to long-term significant hyperuricemia. After suffering from gout, you should go to the hospital in time to diagnose and control the development of the disease.

Gout is a group of syndromes caused by abnormal purine metabolism in the body, and hyperuricemia is a stage in the development of its lesions. Depending on the cause, it can be divided into two types: primary gout and secondary gout. Primary gout has an obvious familial genetic tendency, which is more common in middle-aged and elderly people, with a peak incidence of 30 to 50 years old, about 95% of men, and 5% of women often develop after menopause.

Secondary gout has a slow onset except for congenital tubular dysfunction and chronic renal failure.

In addition, you can try Yu Rong Acid Reduction to reduce the formation of uric acid and facilitate the excretion of uric acid. Many of the onset is acute.

1) Eat reasonably, control the amount of food, and maintain an ideal weight. (2) Increasing the proportion of staple foods rich in carbohydrates, such as rice, pasta, etc., is conducive to promoting.

Discharge of incoming uric acid. (3) Protein intake at the ratio of 1 gram per kilogram of body weight, the provider of protein is mainly eggs and milk, and meat should be boiled and eaten in soup.

There are few symptoms before the attack of gout, but gout attacks on the basis of hyperuricemia, and if you find that uric acid is too high, you should pay attention.

Prevention and treatment of high uric acid requires you to develop good living habits, go to bed early and get up early, don't stay up late, exercise your body moderately, maintain a healthy weight, but fat is not too thin, eat less high-purine foods in your diet, such as seafood, animal offal, broth, etc., not at all, but in moderation, not every day.

If you find that your uric acid is high, go to the hospital to see a doctor in time, if it is more serious, then take medicine obediently, pay more attention to life, if you are lucky and not serious, life adjustment can be, then drink more Bee Baoyuan, drink more boiled water, maintain good living and eating habits, the most important thing is to stick to it, and go to the hospital for regular check-ups.

Red, swollen, hot, and painful joints are a precursor to gout! Keep in mind 4 words, diuresis, swelling and uric acid.

According to my experience, if the uric acid is high, it is easy to have inflexible fingers, figuratively speaking, it is inflexible and a little swollen when the fingers are bent.

Gout is a sudden illness. Most people with gout have no aura before the onset of gout. They usually have elevated blood uric acid for many years before the onset of the disease, but usually have no symptoms.

There are no aura symptoms in an acute gout attack. A small number of patients present with symptoms of fatigue, allergies, and mild joint pain prior to the onset of illness. In the case of fatigue, it often occurs suddenly, and the pain is unbearable at the time of the attack.

At this time, they often go to the emergency room for medical attention.

Acute gouty arthritis can be triggered by acute gout arthritis without any aura, mild trauma, overeating of high-purine foods or excessive alcohol consumption, surgery, fatigue, emotional stress, and medical emergencies (such as infection, vascular blockage) can induce acute attacks of gout, acute monoarticular or polyarticular pain that often occurs at night is usually the first symptom, the pain is progressively aggravated, severe pain, and the signs are similar to acute infection, swelling, local fever, red and obvious tenderness, etc., local ** tension, fever, shiny, dark red or purple-red appearance, Metatarsophalangeal joint involvement of the big toe is the most common (foot gout), as are the arches, ankles, knees, wrists, and elbows, and systemic manifestations include fever, palpitations, chills, malaise, and leukocytosis.

The first few episodes usually involve only one joint, usually only for a few days, but later can invade multiple joints at the same time or successively, if it is not ** can last for several weeks, and finally local symptoms and signs subside, joint function is restored, the length of the asymptomatic interval varies greatly, as the disease progresses shorter and shorter, if not prevented, several attacks per year, chronic joint symptoms appear, and permanent destructive joint deformities occur, the joints of the hands and feet are often limited in movement, in a few cases, sacroiliac, Joints such as sternoclavicular or cervical spine can also be affected, urate deposits are common in the mucus sac wall and tendon sheath, enlarged tophi can appear in the hands and feet and discharge chalky urate crystal fragments, and gout caused by cyclosporine mostly occurs in ** large joints, such as hip and sacroiliac joints, and can also be seen in the hands, and even destroys the renal tubules.

1. Asymptomatic period.

Serum urate concentration increases with age and there are gender differences, and this stage is mainly manifested by a persistent or fluctuating increase in blood uric acid, from the increase in blood uric acid to the onset of symptoms for several years to decades, and only when arthritis occurs is called gout.

2. Acute arthritis attack.

It is the most common first symptom of primary gout, which is more common in the joints of the lower limbs, with the hallux and the first metatarsophalangeal joint as the most common, the initial onset is monoarticular inflammation, and the affected joints are increased, and the onset of gout indicates that the blood uric acid concentration is supersaturated for a long time, resulting in the deposition of a large amount of urate in the tissue.

3. Intermittent period.

Gout attacks last for a few days to a few weeks and can be relieved naturally, leaving no sequelae and completely recovering, and then there is an asymptomatic phase, called the acute attack intermittent period, after which it can recur, about 60% of patients within 1 year**, and the intermittent period is also as long as more than 10 years.

4. Tophi.

And chronic arthritis stage of patients who have not ** or ** poor, urate crystals are deposited in cartilage, tendons, bursal fluid and soft tissues, tophi is a common manifestation in this period, often occurs in the ear wheel, extensor side of the forearm, metatarsophalanges, fingers, elbows, etc., urate deposition increases in the joint, inflammation reverses into the chronic stage and can not disappear completely, causing joint bone erosion defects and fibrosis of surrounding tissues, making joints stiff and deformed, limited activities, with the reversal of inflammation, the lesions are getting more and more aggravated, Seriously affect joint function, early prevention and treatment of hyperuricemia, patients may not have the manifestations of this stage.

The first symptom of gout is mainly pain in joints such as toe or ankle joints, and uric acid testing is required to confirm the diagnosis. If uric acid is elevated, the diagnosis of gout can be confirmed. If the diagnosis is confirmed, it is recommended to take oral anti-gout drugs such as colchicine and allopurinol**, pay attention to a light diet, drink more water, eat more alkaline foods, promote uric acid excretion, do not drink alcohol, and do not eat purine-containing foods such as seafood, animal fats and animal offal.

Gout (gout) is a disease caused by purine metabolism disorders, the incidence rate in China was low in the past, with the improvement of people's living standards, gout has become a common disease and frequent disease in recent years. A set of authoritative survey data is shocking, in the past two or three years, the number of gout patients in China has more than doubled, of which 95% are men, and it has been clinically found that gout patients in China have a trend of younger development, which has aroused a high degree of vigilance and attention in the medical community.

Early symptoms. 1) Acute arthritis occurs more than 1 time per month;

2) Inflammation back-check peaked within 1 day;

3) acute monoarthritis attacks;

4) Diseased joints can be seen** dark red;

5) pain or swelling of the first metatarsophalangeal joint;

6) the onset of single-bond arthritis, involving the first metatarsophalangeal joint;

7) Single-bond arthritis attacks, involving the tarsal joints;

8) Have suspicious gouty nodules;

9) hyperuricemia;

10) X-ray examination shows asymmetrical intra-articular swelling;

11) X-ray examination showing submyclonial cyst without erosion;

12) Negative microbial culture of synovial fluid during arthritis attacks.

1) Nucleic acids and other purine compounds produced by protein catabolism in human cells are generated by the action of some enzymes to produce endogenous uric acid.

2) The purine compounds, nucleic acids and nuclear proteins contained in food are digested and absorbed, and exogenous uric acid is formed by the action of some enzymes.

The production of uric acid is a complex process that requires the involvement of some enzymes. These enzymes can be broadly divided into two categories: enzymes that promote uric acid synthesis, mainly 5-phosphonucleic acid-1-pyrophosphate synthase, adenine phosphonucleotidyl transferase, phosphoribose pyrophosphate amide transferase, and xanthine oxidase; Enzymes that inhibit uric acid synthesis, mainly hypoxanthine-guanine nucleoside transferases.

Gout is caused by various factors that cause the abnormal activity of these enzymes, such as promoting the increased activity of uric acid synthase and inhibiting the activity of uric acid synthase, resulting in excessive uric acid production. Or due to various factors, the kidneys have a disorder of uric acid excretion, which causes uric acid to accumulate in the blood, resulting in hyperuricemia.

If hyperuricemia persists for a long time, uric acid will be deposited in the form of urate in the joints, subcutaneous tissues and kidneys, causing a series of clinical manifestations such as arthritis, subcutaneous gouty stones, kidney stones or gouty nephropathy.

This disease is the first acute or chronic arthritis of the peripheral joints, which is caused by the deposition of monosodium urate crystals in and around the joints, tendons and body fluids of supersaturated hyperuricemia.