Can you take medicine after eating grapefruit, can you not eat yuzu just after taking medicine

For example, blood pressure medication can not be taken with grapefruit.

Grapefruit is a common fruit in our lives, and many people love to eat it, and now many people have high blood pressure, so they need to take blood pressure medication regularly, but do you know some of the contraindications when taking blood pressure medication. So, can't you eat grapefruit when taking blood pressure medication? Let's take a look.

Grapefruit contains furanocoumarin, which affects an enzyme in the human liver and reduces its activity, and the main role of this enzyme is to metabolize drugs. After the activity is reduced, the effect on drug metabolism is also greatly reduced, which increases the concentration of drugs in the blood and increases the accumulation and toxicity of drugs. In addition, there is another substance in grapefruit, naringenin, which speeds up the absorption of the drug in the intestines and also increases the concentration of the drug in the blood.

Grapefruit and certain blood pressure medications should not be taken at the same time. The main ones are drugs like calcium antagonists. Furancoumarins can affect the function of an enzyme in the human liver, which greatly reduces the metabolism of this enzyme on drugs, resulting in an increase in blood concentrations in the body.

At the same time, naringenin, another ingredient in grapefruit, will speed up the intestinal absorption of the drug. If the drug is absorbed too quickly and metabolized too slowly, the concentration of the drug in the blood will be too high.

Antihypertensive drugs can not be eaten with citrus fruits such as grapefruit, and it has been clinically found that patients with hyperlipidemia take a cup of grapefruit juice to take a lipid-lowering tablet is equivalent to taking 12 l5 tablets of similar drugs with a glass of water to lower blood lipids, and the patient will have muscle pain and even kidney lesions. Some patients who eat grapefruit or drink grapefruit juice while taking the anti-allergic drug terfenadine may experience dizziness, palpitations, arrhythmias, etc., and may die suddenly in severe cases.

How Long After Taking Anti-Inflammatory Drugs Can I Eat Grapefruit.

Grapefruit contains an unknown active substance, which has an inhibitory effect on an enzyme in the human intestine, which interferes with the normal metabolism of the drug and increases the blood concentration of the drug significantly. It affects liver detoxification, impairs liver function, and may also cause other adverse reactions, and even poisoning. Studies have found that the blood concentration of taking medicine after eating or drinking grapefruit juice may increase several times to hundreds of times compared with that after drinking water; If you take the medicine after drinking grapefruit juice for a period of time, it is found that the effect of grapefruit juice on the increase of blood concentration can last for 24 hours; Only after 3 7 days does the effect of grapefruit juice gradually wear off.

Therefore, to be on the safe side, you should avoid eating or drinking grapefruit juice for 3 days before and 6 hours after taking the medicine, and it is best not to eat fruits such as citrus. Otherwise, you should consult your doctor to adjust the dosage of the drug or switch to another drug as prescribed.

Don't eat fruit just after taking the medicine

Don't eat grapefruit right away after taking the medicine! It's very dangerous to do that!

To be on the safe side, you should avoid eating or drinking grapefruit juice for 3 days before and 6 hours after taking the medicine, and it is best not to eat fruits such as citrus.

Grapefruit contains an unknown active substance, which has an inhibitory effect on an enzyme in the intestinal tract of the human body, which interferes with the normal metabolism of the drug, and makes the blood concentration of the drug increase significantly. It affects liver detoxification, impairs liver function, and has the potential to cause other adverse reactions, and even poisoning.

Studies have found that the blood concentration of taking medicine after eating or drinking grapefruit juice will increase several times to hundreds of times compared with that after drinking water; When taking the medicine after drinking grapefruit juice for a period of time, it was found that the effect of grapefruit juice on the increase of blood concentration could last for 24 hours. Only after 3 7 days does the effect of grapefruit juice gradually wear off.

1 grapefruit itself is rich in potassium, has a certain antihypertensive effect, but also can increase the blood concentration of antihypertensive drugs, if you eat grapefruit or drink grapefruit juice during the period of taking antihypertensive drugs, it is equivalent to increasing the dose of antihypertensive drugs, in this case, it is easy to cause blood pressure to drop too violently, causing dizziness and fatigue, and causing angina, myocardial infarction and even stroke, which is life-threatening.

2. Eating grapefruit or drinking grapefruit juice while taking hypolipidemic drugs will lead to a large accumulation of drugs in the body, which is easy to increase the risk of liver damage and rhabdomyolysis. This is mainly due to the joint action of the chemicals in grapefruit and drugs, which causes damage to the striated muscles, which can easily lead to muscle soreness, fatigue, myoglobinuria, and then kidney failure, and even life-threatening.

3. If you eat grapefruit during taking sleeping pills, grapefruit is easy to delay the metabolism of sleeping pills, prolong the time for the drug to take effect, thereby aggravating the symptoms of dizziness and drowsiness, and the next day after taking the drug, it is easy to have a feeling similar to a hangover, and the common symptoms are dizziness and headache.

4. Eating grapefruit or taking contraceptive pills with grapefruit juice while taking contraception, some components in grapefruit are easy to hinder the absorption and utilization of contraceptive pills by the human body, inhibit the metabolism of human enzymes, and cause the drug to fail to work, resulting in contraceptive failure.

It's time for grapefruit to be on the market in large quantities again, and some friends think: you can't eat grapefruit when taking medicine. Actually, this statement comes from a pamphlet published by the FDA a few years ago, in which it admonished:

Patients should not drink grapefruit juice when taking the anti-allergic drug terfenadine, or other similar drugs diphenhydramine hydrochloride. Because studies have shown that the interaction of grapefruit with the anti-allergic drug terfenadine can cause ventricular arrhythmias and even fatal ventricular fibrillation.

In recent years, it has been reported that statin lipid-lowering drugs should not be taken with grapefruit, otherwise it will increase the blood concentration of statins. In February 2005, the British authorities again issued a warning to patients taking hypolipidemic drugs not to eat or drink grapefruit juice while taking the drug. Researchers from the University of Ontario, Canada, found that when taking 1 tablet of the lipid-lowering drug "lovastatin" with 1 cup of grapefruit juice, the concentration of "lovastatin" in the blood was 10 to 15 times higher than that of taking it with 1 cup of water.

In other words, even if you take the medicine in a normal dose, if you eat or drink yuzu juice at the same time, the result is equivalent to an overdose, which may cause poisoning.

Clinical experiments abroad have shown that if you take the medicine after drinking grapefruit juice, the blood concentration may increase several times to hundreds of times compared with that after drinking water; If you take the medicine after drinking grapefruit juice for a period of time, it is found that the effect of grapefruit juice on the increase of blood concentration can last for 24 hours; Only after 3 7 days does the effect of grapefruit juice gradually wear off. Therefore, to be on the safe side, pharmacologists recommend that grapefruit should be avoided for 3 days before and 6 hours after taking the drug.

In short, the drugs that are currently considered not to be taken with grapefruit are: (1) statins, such as lovastatin, Xuezhikang, Shuzhizhi, and Lipitor; (2) calcium antagonists, such as benzodipine, nipicdipine, nimodipine, nisoldipine, feledipine; (3) Valium-based drugs, such as sulazepam and gallodine; (4) antihistamines, such as terfenadine; (5) Immunosuppressants, such as cyclosporine.

The drug and grapefruit can cause the above adverse reactions, and there are no special studies reported in China. However, for the sake of safety, patients (especially the elderly) should avoid consuming grapefruit or grapefruit juice while taking the above medications.

Generally, try not to eat fruit half an hour before and after medication, and some drugs are easy to react with fruits and affect the effect of drugs. It is best to take the medicine after eating the grapefruit for more than half an hour, or take the medicine first and eat the yuzu for more than half an hour.

Grapefruit is a kind of fragrant, sweet and sour, cool, nutritious, and highly medicinal value, but the doctor reminds that grapefruit should not be taken with medicine, and it is best to eat it 6 hours after the fertilizer.

Yes, grapefruit does not conflict with any medicine.

That's not true. If it is a Chinese herbal medicine, it is not appropriate to eat grapefruit, because it is relatively cool and easy to degrade the medicinal effect.