Analysis of the causes of poor sleep in Parkinson s disease patients?

Parkinson's disease patients do not sleep well, this big problem, greatly affects the physical and mental health of Parkinson's disease patients, the family is also very worried, in order to improve the patient's sleep problems, try all kinds of ways, filial children may also buy a variety of health products to help sleep, but sometimes the effect is very little, so what is the reason for Parkinson's disease patients do not sleep well? Sleep problems include insomnia, poor sleep quality, and many nightmares. The pathological Parkinson's disease of Parkinson's disease itself also has an effect on the structure and transmitters of the sleep center, and in Parkinson's disease, dopaminergic neurons in the substantia nigra of the brain are lost, resulting in an imbalance of transmitters in the brain.

This is the biochemical basis that causes sleep disorders. These can promote the occurrence of sleep disturbances and affect daytime awakenings. Poorly controlled Parkinson's disease symptomsAs the disease progresses, nocturnal dyskinesia is more common in patients with Parkinson's disease, with nocturnal movement symptoms such as nocturnal freezing, akathisia, restless legs and tremors becoming more severe, and early morning dystonia.

Periodic limb movement disorder and rapid eye movement sleep disorder can cause insomnia in Parkinson's patients, and bladder disorders such as nocturia, frequent urination, and urgency can also affect the sleep of replacement patients.

The exact cause of Parkinson's disease is still unknown. Genetic factors, environmental factors, aging, and oxidative stress may all be involved in the degenerative death process of PD dopaminergic neurons.

It is normal for Parkinson's patients to have poor sleep. For patients with Parkinson's disease, sleep disorders are very common, and some patients will have stiffness and pain all over the body because the drug dose of Parkinson's disease is not enough, which is particularly obvious at night, which seriously affects the patient's sleep. There are also some patients with Parkinson's disease will have rapid eye movement sleep behavior disorder, manifested as yelling, punching and kicking in sleep, which is also an important non-motor symptom of Parkinson's disease, therefore, improving sleep is very important for patients, if the patient because of muscle stiffness and pain, sleep is not good, you can take an appropriate amount of levodopa drugs before going to bed, you can also use non-benzodiazepine hypnotic drugs, for rapid eye movement sleep behavior disorder, it is recommended to use long-acting benzodiazepines.

Patients with advanced Parkinleaker disease are often compromised with impaired autonomic function, and increased nocturia caused by regression can also affect sleep.

At the same time, Parkinson's disease, movement disorders, and difficulty in turning over, difficulty or painful convulsions often lead to frequent awakenings at night, resulting in sleep fragmentation and affecting sleep quality.

This disease is now a medical problem in the world, and whoever says that it can be cured of this disease is the best of the best!

Because the disease and its pathogenesis have not yet been clarified, it may be related to social factors, drug factors, patient factors, etc. Existing medical technology cannot be used to improve Parkinson's disease. For patients, it is mainly to reduce the pain, delay the development of the disease, and improve the quality of life of the patients.

Therefore, one of the key points is to adopt a comprehensive system based on exercise to improve the patient's function and improve the quality of life. Relying on what so-called Chinese medicine decoction can ** the disease is completely a kind of boasting and routine of Jianghu doctors. Stop stupidly sending them money to make changes!

Then you need to use some drugs in combination.

1. Dinner is carbohydrate-based, which helps to increase drowsiness.

2. Patients with more nocturia should drink less water and empty their bladder before going to bed, and place a light bedpan next to the bed to facilitate urination.

3. Adjust the psychological state and cultivate good sleep habits, and the spouse of Ji Huaiyin should comfort and encourage the patient and maintain a quiet environment.

4. Adjust the dosage and administration time of Parkinson's disease. For some drugs that are openly taken too close to sleep time to cause insomnia, it is best to change to morning medication or reduce the dose.

5. For patients with difficulty turning over and insomnia caused by painful convulsions, adding a small dose of dopamine before bedtime can improve sleep consistency.

6. If necessary, hypnotics with fast onset and rapid metabolism can be used, but long-term use of sleeping pills is easy to form dependence, and patients who are older or have dementia should not use them.

People with Parkinson's disease need to have a regular sleep schedule to avoid sleep disturbances. After exercising during the day, do not take a nap and exercise regularly every day to help Parkinson's disease patients fall asleep better at night. Due to the use of monoamine oxidase B inhibitors and amantadine drugs, the patient cannot sleep in the oak dress.

In this case, you can change the time of the medication to be taken in the morning or noon. If taking a dopamine agonist causes the patient to be excessively sleepy during the day, the medication may need to be changed or the patient may be asked to do something during the day to stay awake.

Many Parkinson's patients complain of poor sleep, insomnia, daytime sleepiness, nightmares, etc., these sleep disorders affect the physical health and life of Parkinson's disease patients, so what are the causes of sleep disorders in Parkinson's disease patients?

One is difficulty falling asleep or waking up early due to poorly controlled Parkinson's disease symptoms, such as poorly controlled tremor, which often leads to difficulty falling asleep; In sleep, muscle stiffness often causes patients to wake up early, resulting in difficulty turning over on their own or spasms in their limbs. If this is the case, first consider adjusting the medication and increasing the dose or frequency of anti-Parkinson's disease drugs to control the symptoms of Parkinson's disease and improve sleep disorders.

The second is drug overdose, some drugs are taken too late, which may cause cerebral cortex excitation and cause insomnia, so when the patient visits, tell the expert about the sleep problem, the expert understands the drug, and will make drug adjustments according to the patient's condition.

The third is the mental symptoms of Parkinson's disease patients, such as anxiety and depression, which will affect the quality of sleep. There is a category of such emotions that the patient thinks of his condition and is depressed, and if the ** effect is good, his mood may improve. On the other hand, even if the condition improves, the patient's mood does not improve.

Therefore, it is necessary to be targeted, to do a good job in the patient's ideological work, communicate more, soothe the patient's emotions, and establish confidence in overcoming the disease. In the latter case, antidepressant medications can be used appropriately**.

The insomnia of Parkinson's disease patients is different from the insomnia of other people, and the insomnia of other people is mainly related to anxiety, psychological stress, poor living habits, and poor sleep environment, while the insomnia of Parkinson's disease patients is more directly related to the interference of Parkinson's disease symptoms and the interference of drugs.

There are several main reasons:

1. The dose of drugs at night is insufficient, which makes it difficult for the patient to move and turn over;

2. Spasms, pains and various physical discomforts in the limbs may cause patients to sleep poorly.

3. If the dose of drugs before going to bed is too large, patients with Parkinson's disease will have involuntary movements, sometimes accompanied by indescribable discomfort, anxiety and restlessness, which will affect sleep.

4. The effects of Parkinson's disease drugs, such as amantadine, selegiline, etc., have a certain interference effect on sleep, so try to avoid using them before going to bed.

The non-motor symptoms of Parkinson's disease, such as frequent urination and urgency, can exacerbate insomnia, repeatedly get up to go to the toilet, and Jane Na not only interferes with the sleep of Parkinson's disease patients, but also increases the risk of falling down when patients get up at night, which requires more effort and patience from patients and their families.

Poor sleep in patients with Parkinson's disease Sleep disturbance is the focus of non-motor symptoms, mainly due to emotional abnormalities, such as depression, which leads to difficulty falling asleep.

On the other hand, patients are prone to restless leg syndrome and periodic Kaiqiao's leg movements, generally when sleeping at night, patients always have small movements of limbs, and feel that the limbs are particularly uncomfortable, so they want to move.

There is also a kind of periodic leg shaking after sleep, which is easy to affect the patient's deep sleep, and the patient can not always enter the state of deep sleep, and there is no sense of recovery from sleep.

Therefore, the sleep disorder of Parkinson's patients is due to damage to the brain and sleep-related centers.