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Western medicine believes that MND is a progressive chronic neurological pathology, which is more likely to invade the anterior horn cells of the spinal cord, the motor nerve nucleus of the brainstem, the cerebral cortex and the pyramidal tract, so patients often have symptoms such as muscle weakness, muscle atrophy, muscle beating and increased muscle tone. The specific manifestations of the lower limbs are weakness in walking, unsteadiness, easy to fall or procrastination; The specific manifestations of the upper limbs are inflexible fingers and slow movements. In addition, a small percentage of patients present with dysphagia, speech dysfunction, or breathing disorders.
Symptoms of MND vary depending on the type. There are several special classifications of this disease, the most common is amyotrophic lateral sclerosis, the characteristics of the disease include slurred speech, swallowing regurgitation, sometimes dyspnea, muscle atrophy of the upper limbs, from the distal end, that is, the fingers gradually upward, and even to the scapula, weakness and muscle atrophy of the scapula, and the lower limbs are a kind of rigidity, that is, spasmodic limb weakness; There is also progressive spinal muscle atrophy, which is mainly weakness and atrophy of the limbs, as well as muscle atrophy and progressive bulbar paralysis, mainly problems with swallowing, chewing or breathing.
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Pathologic manifestations of motor neuron disease with macroscopic atrophy and thinning of the spinal cord. Under light microscopy, the anterior horn cells of the spinal cord were degenerated and lost, with the cervical spinal cord being obvious, followed by the thoracolumbar medulla. In patients with sporadic amyotrophic lateral sclerosis, there is a ubiquitinated inclusion body in the cytoplasm of neuronal cells, which is a characteristic pathological change of amyotrophic lateral sclerosis.
In patients with familial amyotrophic lateral sclerosis, a different inclusion body may be observed. Different degrees of glial hyperplasia, phagocytosis are not obvious, the anterior roots of spinal nerves are thinned, myelin sheath is lost, and fibers are reduced. Degeneration of the pyramidal tract progresses distally to proximal, with demyelination and axonal degeneration, and sometimes changes in other tracts, with denervated atrophy of muscles.
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Motor neuron disease begins with symptoms in the hands, followed by progressive muscle atrophy in the distal limbs, and more than half of the patients have muscle atrophy in the early hand-sized thenar, and then extends to the forearm muscles, pectoralis major muscles, back muscles, etc. Causes hypertonia, difficulty moving, breathing and swallowing disorders, and fasciculations. The following are typical symptoms of motor neurons.
1. The first symptom of motor neuron is on the hand, and the patient will feel stiff and clumsy fingers, weak movements, gradual atrophy of hand muscles and fasciculations.
2. It can also lead to tongue muscle atrophy with tremor, resulting in slurred speech, difficulty swallowing and chewing weakness, and later will lead to systemic muscle atrophy, bedridden, respiratory insufficiency, belonging to the type of lower motor neurons.
3. Motor neurons can cause limb weakness, muscle tension and difficulty walking, this phenomenon belongs to the type of upper motor neurons, most patients develop the disease after adulthood, and the progress is usually slow.
4. Motor neurons include a mixed type of upper and lower motor neurons, which manifests as symptoms such as myasthenia gravis and atrophy of the hand. In the later stages of the disease, muscle wasting and atrophy throughout the body, inability to raise the head, difficulty breathing, and bedridden.
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Motor neuron is also known as ALS, as the name of the disease suggests, patients will gradually appear as if they are "frozen", and the patient will gradually develop from limb weakness to muscle atrophy; The limbs gradually develop from the hands and feet, and eventually to the torso. Patients may experience dyspnea, dysphagia, and most eventually die of paralysis of the respiratory muscles. At present, Western medicine does not have a good method for motor neurons, but there is no way for motor neurons, and choosing the right professional method as soon as possible plays a vital role in motor neurons.
Motor neuron is an incurable disease, and the most important thing is to treat the symptoms**, so that it will slowly recover.
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Beijing Deshengmen Hospital of Traditional Chinese Medicine - Liu Quanpeng - Department of Impotence - Deputy Chief Physician - Clinical symptoms of motor neurons.
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Motor neuron will affect the patient's physical health, after the onset of the patient's nervous system will have abnormal changes, this time should be based on the motor neuron lesions, the most important thing is to understand the condition clearly, relying on the actual performance to judge the patient's condition, which is the most important thing to pay attention to.
Clause. 1. Motor neuron disease will have language disorders, which will affect the patient's language system, and the language is ambiguous, and even there is a language expression disorder, which is caused by motor neuron abnormalities, and the symptoms of this motor neuron abnormality will not only affect the language, but also have more manifestations that patients need to pay attention to.
Clause. 2. Motor neuron disease can cause autonomic dysfunction, no sensory impairment, loss of urinary and urinary function, and no way to live normally, which is a relatively serious physiological disorder. In the process of physical and psychological disorders, patients should go to the hospital as soon as possible for examination to determine the physical impact of MND.
Clause. 3. Motor neurons can cause many complications in the early stage, such as progressive amyotrophy, and even amyotrophic sclerosis and other phenomena are caused by the occurrence of the disease, which is mainly manifested as small muscle atrophy of one hand or both hands in the early stage, and this muscle atrophy will become more and more serious in the later stage.
Clause. Fourth, motor neuron disorder will cause more and more problems to patients, especially the patient's muscle stiffness, and even the weakness of both lower limbs is the most common, at this time the patient should go to the hospital as soon as possible, otherwise the impact of motor neuron disorder on patients will be more and more.
In short, it is a kind of motor nervous system disease, which includes muscle atrophy, muscle jumping hands and feet, stiffness and inconvenience to walk.
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Motor neuron disease usually has an insidious onset and a slow progression. Due to the different locations of injury, the clinical manifestations are different combinations of symptoms such as muscle weakness, muscle atrophy, and bulbar paralysis. In many cases, one type of presentation is present, followed by another, and finally ALS.
As a result, it can sometimes be difficult to determine which type it belongs to in the early stages of the disease.
1. Typical symptoms.
1. Amyotrophic lateral sclerosis: The common first symptom is clumsiness and weakness of one or both fingers, followed by atrophy of small finger muscles, which gradually develops to the muscles of the forearm, upper arm and shoulder. As the disease progresses, muscle weakness and atrophy extend to the trunk and neck, and eventually to the facial and laryngeal muscles.
In a few cases, muscle atrophy and weakness begin in the lower extremities or trunk. Fasciculations are often evident in the affected area.
2. Progressive amyotrophy: The common first symptom is atrophy and weakness of small muscles in one or both hands, which gradually affects the muscles of the forearm, upper arm and shoulder. Affected muscles are markedly atrophied, muscle tone is reduced, and muscle tremors may be seen.
3. Progressive bulbar paralysis: the main manifestations are progressive slurred articulation, dysphagia, choking on drinking water, and weakness in chewing. The tongue muscles are obviously atrophied, and there are fasciculations, and the lip muscles and throat muscles are atrophied.
This type of disease progresses rapidly, and most of them die within 1 to 2 years due to respiratory muscle paralysis or lung infection.
4. Primary lateral sclerosis: the common first symptom is symmetrical stiffness and fatigue of both lower limbs, and walking with a scissor gait. Progresses slowly and gradually affects both upper extremities. There is usually no muscle atrophy and fasciculations, and no sensory deficits. This type progresses slowly and can survive for a long time.
2. Other symptoms.
A small percentage of patients with motor neuron disease have manifestations outside the motor system, such as dementia, paresthesia, and urinary and urinary dysfunction, and a small number of patients have extraocular muscle movement disorders.
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Motor neuron disease (MND) is a degenerative disease of the nervous system, which is generally caused by lesions of upper and lower motor neurons, causing a series of chronic progressive symptoms of the nervous system. The more common is amyotrophic lateral sclerosis, which affects both upper and lower motor elements, causing muscle weakness, atrophy, bulbar palsy, and pyramidal tract signs, but sensory nerves are not affected, and bowel and bowel movements are normal. The disease generally begins in middle age and varies in duration, with a higher prevalence in men than in women between 2 and 10 years.
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The symptoms of motor neuron disease are insidious in the early stage, which can be manifested as a feeling that the tongue is a little clumsy when speaking, and the family does not feel that the patient has dysarthria. After about half a year, the patient will have muscle atrophy of the upper limbs, muscle volume will be reduced, and the muscles of the hand will also appear in a state of atrophy, and the thenar muscle will first appear atrophy.
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Motor neuron disease is a neurodegenerative disease that primarily affects the motor system and not the sensory system. Motor neuron disease (MND) also invades upper and lower motor neurons, and often begins with weakness of the small muscles in one hand, accompanied by atrophy, and gradually progresses to other limbs, eventually affecting the respiratory and swallowing muscles, causing dyspnea and swallowing.
Motor neuron disease often progressively worsens, the course of the disease is about 3-5 years, you can come to Beijing Renxuan TCM to find Sheng Jinqiangfu**, through Yiyuan Muscle Formula one-to-one conditioning, can improve the patient's symptoms.
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1. Neuritis refers to the inflammation, decline or deterioration of nerves or groups of nerves, and its symptoms are the same as those of the disease. The main manifestations are symmetrical sensation, movement, autonomic dysfunction of the distal limbs, the patient may present with numbness, pain, ant crawling sensation at the end of the limb, mainly manifested as sock-like or glove-like, symmetrical numbness symptoms, the patient may appear tingling, tenderness.
2. There may be symptoms of motor function decline, muscle weakness, muscle atrophy, joint stiffness, and can also be accompanied by symptoms of autonomic nerve dysfunction such as sweating, physical discomfort, nail tarnishing, roughness, dryness, abnormal urine and bowel movements, and it is also easy to be accompanied by abnormal emotions, such as anxiety, depression, irritability, insomnia, dreaminess, sleep disorders and other symptoms. It will affect movement, cause movement disorders, such as unsteady standing, ankle pain and numbness, etc., and will cause tingling when running.
3. Eat more fresh vegetables for neuritis. People with neuritis should eat more vegetables. Proper consumption of some soy products or dairy products plays a good role in the onset of neuritis, which can replenish the protein needed by the body.
Eating more fresh vegetables can promote gastrointestinal peristalsis and improve human immunity. Kelp, red dates, bitter gourd, loofah, winter melon, cucumber and other foods are nutritious, can supplement the vitamin C needed by the human body, and have a good effect on alleviating neuritis. Secondly, ginger sugar soda leaf drink.
4. This kind of food is nutritious and can dispel cold. In the case of neuritis, this diet** can be chosen to improve the condition. Mints.
Menthol has a high base and high nutritional value. Patients with neuritis usually consume menthol appropriately, which has a certain effect on promoting blood circulation and dredging the veins. It has a good effect on the adjunct of neuritis**.
Menthol in water and taken daily with warm boiled water has a good effect on the adjunct of neuritis**.
The early stage of motor neuron disease is characterized by gradual muscle atrophy and weakness in one part of the patient's body, and many diseases have similar clinical manifestations in the early stage, and the age of onset of this disease is between 40 and 60 years old, which is also the stage of high incidence of cervical spondylosis. Many patients with cervical spondylosis can also have unilateral limb muscle atrophy and weakness in the early stage, so many patients mistakenly believe that it is cervical spondylosis, delaying the diagnosis. There is no difficulty in an advanced ALS person, and the diagnosis can be made by simply taking clinical data, but the difficulty in the examination of motor neuron disease is when it is atypical in the early stage, and it may be difficult to determine that it is an area of disease if there is no experience. >>>More
The clinical manifestations of motor neuron disease are mainly lack of strength and muscle atrophy, the muscle atrophy is mainly interosseous muscles and thenar muscles, no strength is first manifested as the inability to lift heavy objects, at this time the condition is mild, will not affect daily life, when the disease further develops, there may be dysphagia, hoarseness, etc., in severe cases, there will be paralysis of respiratory muscles, and then severe respiratory suffering and life-threatening, but the body's sensory nerves are not damaged, all sensations are normal.
The main symptoms of motor neuron disease are muscle weakness and atrophy, but motor neuron disease is divided into many types according to the location of its onset, and there are several main types, we often say that there is amyotrophic sclerosis, this disease is often the distal end of the upper limbs, that is, the small muscles of the hands mainly begin to atrophy, and it is easy to fall off when holding things, and gradually develops to the opposite upper limbs, and then to the lower limbs; Another type is called bulbar palsy, its onset is the muscles of our throat or tongue muscles disease, then the main symptoms are the beginning of unclear speech, choking on drinking water, difficulty swallowing, this disease will progress relatively quickly, may soon develop to the upper limbs, the appearance of upper limb weakness; There are other types, such as primary lateral sclerosis, which often begins in the lower extremities, and it is more difficult to walk, and the disease progresses more slowly.
There are three clinical types of MND, the early symptoms of MND vary depending on the type, the lower MND usually begins with small muscle weakness and gradual muscle atrophy in the hand, which can affect one side, both sides, or start on one side and then spread to the opposite side. The upper motor neuron type is characterized by limb weakness, tightness, and ineffective movements, and the upper and lower motor element mixed type usually has hand muscle weakness and muscle atrophy as the first symptoms, which generally starts from one side and then spreads to the opposite side, and the symptoms of mixed damage of upper and lower motor elements appear with the development of the disease, which is called amyotrophic lateral sclerosis.
Since the nature of MND is unclear, there is no specific approach. >>>More