What are the advantages of inhaled corticosteroids? What does it do?

It can prevent and treat asthma, can also make people wake up from sleep, can also effectively prevent inflammation, has many benefits to the body, is a safe drug, can be the best for many diseases. It has an anti-inflammatory effect, can be antiviral, can also resist immunity, can also prevent shock, can be used for various disease states, can also be experimented**.

There is a clear difference between glucocorticoids and mineralocorticoids, and the sites of glucocorticoids and mineralocorticoids are different. Although both are secreted by the adrenal glands, glucocorticoids are secreted in the globular zone of the adrenal glands, and mineralocorticoids are secreted in the adrenaline bundle zone. Glucocorticoids and mineralocorticoids play different functions in the human body.

In the human body, it mainly plays a role in regulating blood pressure and regulating calcium metabolism in patients, mainly mineralocorticoids, and in vivo to maintain human glucose metabolism, ester metabolism, protein synthesis and metabolism and rely on glucocorticoids. Therefore, glucocorticoids and mineralocorticoids are one of the indispensable hormones in the human body, but there are still differences.

Introduction: As long as we talk about hormones, most people will think of buffalo back, obesity, and hirsutism. And once the child ingests hormones, parents will be particularly worried about whether it will affect the child's growth and not be tall.

The well-known hormone usually refers to oral or injection of some glucocorticoids.

Generally speaking, oral administration of some hormones will not cause some adverse reactions, but if you inhale too much, it is a different matter, and the topic I want to share today is, what are the harms of inhaled glucocorticoids?

1. What are inhaled glucocorticoids?

Inhaled corticosteroids are the best and most effective drugs for controlling airway inflammation. A certain amount of aerosol, dry powder and solution are best inhaled. The method of use is that the initial use of glucocorticoids is generally relatively large, so that asthma can be quickly controlled.

and after 3-6 months, the dosage will be gradually reduced, but the minimum dosage should be maintained. For some seasonal asthma, you can take it two weeks before the start of the season, and stop taking it immediately after that.

2. What are the harms of inhaled glucocorticoids?

It promotes the rapid growth of fungi in the oropharynx, and most patients will develop thrush in the pharynx after inhaled glucocorticoids.

symptoms. Moreover, the incidence of this symptom is 13%, because long-term inhalation of glucocorticoids will allow the inhaled drug to be partially deposited in the oropharyngeal mucosa, which will inhibit the mechanism of local immunity, thereby promoting fungal growth and causing disease. Moreover, it will cause the patient's voice to appear hoarse, because the inhalation of glucocorticoids will directly have a significant effect on the vocal cord muscles, causing myalgia, which will weaken the activity of the vocal cord muscles, resulting in weakened voice and hoarseness.

phenomenon. Can cause fungal infections of the esophagus.

It can also have a great impact on the patient's bone mass and growth, and the above is what we want to say about this topic.

Major adverse effects of inhaled corticosteroids include hoarseness, pharyngeal discomfort, and possible Candida infection, but can be avoided by rinsing the mouth with water promptly. If used in high doses for a long time, systemic adverse reactions can also occur, such as osteoporosis and adrenocortical axis inhibition.

It can cause hoarseness, cause oral infections, cause throat inflammation, as well as tracheitis and pharyngitis, which are all harmful.

It can cause weakness in the limbs, hotheadedness, lack of sleep, dizziness, indigestion and loss of appetite.

Glucocorticoids are a class of steroid hormones secreted by the adrenal cortex, which have the role of regulating the biosynthesis and metabolism of sugar, fat, and protein, and also have anti-inflammatory effects.

The basic structural features of glucocorticoids include the carbonyl group, δ4, and 17 ketol side chains of C3 possessed by adrenocorticosteroids, and the 17-OH and 11-OH unique to glucocorticoids

At present, the concept of glucocorticoids not only includes endogenous substances with the above characteristics and activities, but also includes many synthetic drugs with similar structures and activities that have been optimized for structure.

Does glucocorticoids have a () effect?

a.So that the white three with the ene hand hall increases.

b.Increases prostaglandins.

c.Increases platelet-activating factor.

d.Causes thrombocytosis.

e.Increase IL-3.

Correct answer: d

Glucocorticoid is an endogenous hormone and a ** drug with a variety of physiological effects, including anti-inflammatory, anti-allergic, immunosuppressive, metabolic effects, etc. One of the most common effects is anti-inflammatory. Glucocorticoids relieve symptoms of inflammation by inhibiting the synthesis and release of inflammatory mediators and reducing the inflammatory response.

In addition, glucocorticoids can also suppress the activity of the immune system and reduce inflammation-related immune responses, leading to a variety of autoimmune diseases. Glucocorticoids can also affect metabolism, such as increasing glucose synthesis and breakdown, and promoting fat paralysis. However, glucocorticoids also have some adverse effects, such as affecting bone metabolism and immunosuppression leading to infection.

Therefore, when using glucocorticoids, it is necessary to consider and judge comprehensively according to the condition and the specific situation of the patient.

Answer]: c Analysis: Glucocorticoids enter the target cell and bind to the receptor complex in the nucleus to regulate the transcription of inflammation-related genes Inhibition of the expression of certain inflammation-related proteins (cytokines, NO synthase, phospholipase 2, cyclooxygenase); Promote the expression of certain anti-inflammatory proteins (ester quercetin, 2 receptors, vascular pysen, etc.) and have anti-inflammatory effects.

Master the knowledge of "drugs acting on the respiratory system".

inhibits the expression of certain inflammation-related proteins (cytokine traces, NO synthase, phospholipase A2, cyclooxygenase);

Promotes the expression of certain anti-inflammatory proteins (ester-belt, 2-receptor, vasocortin, etc.) and anti-inflammatory effects.